Cyrus Cooper

ObjectivesThis study aimed to examine the association between sleep quality and physical performance among a group of UK community-dwelling older adults, according to sex.MethodsSleep quality was assessed using the Pittsburgh Sleep Quality Index. Physical performance was assessed using a short physical performance battery (SPPB), a timed up-and-go, and a hand-grip strength test.ResultsOf 591 eligible study members, 401 completed the Pittsburgh Sleep Quality Index. In regression analyses, men who reported poor sleep quality were significantly more likely to have a poor SPPB score, even after adjustment for confounding factors (OR = 2.54, 95% CI 1.10-5.89, P= .03). The direction of the relationship was reversed among women, where those who reported poor sleep were less likely to have a low SPPB score (OR = 0.36, 95% CI 0.15-0.85, P = .02). Poor sleep quality was associated with poorer hand …

MethodsThe identification and prioritization of outcomes was conducted following a 3-step procedure:(1) a literature review to generate an initial list of health outcomes of sarcopenia;(2) an expert panel consultation [a European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group in sarcopenia, composed with authors of this paper] to restructure initial outcomes and validate them; and (3) 3 focus groups with sarcopenic participants (recruited in Belgium and Spain) organized to include patients’ opinions on outcome identification, ensure content validity of the list of outcomes, and prioritize the outcomes (from the most to the least important ones). The final selection of the 5 most important outcomes was made by our expert panel based on focus group results and expert’s knowledges. Approval for this study was obtained from the Medical Ethics Committee of the University of Liège that coordinated the project and by the Ethics Committee of the Hospital Universitario Ramón y Cajal, where one of the focus groups was conducted.