Eva L. Feldman
University of Michigan
H-index: 123
North America-United States
Description
Eva L. Feldman, With an exceptional h-index of 123 and a recent h-index of 75 (since 2020), a distinguished researcher at University of Michigan, specializes in the field of neurology, diabetes, neuropathy, ALS, Alzheimer's disease.
His recent articles reflect a diverse array of research interests and contributions to the field:
Peripheral Immune Profiles Predict ALS Progression in an Age-and Sex-Dependent Manner
Gender Differences in Faculty Perceptions of Mentorship and Sponsorship
Professional Experiences and Career Trajectories of Mid-to Senior-Career Women Clinician-Scientists: A Qualitative Study
Neuropathic Pain With and Without Diabetic Peripheral Neuropathy in Type 1 Diabetes
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis
Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort
Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy
Professor Information
University | University of Michigan |
---|---|
Position | Professor |
Citations(all) | 61738 |
Citations(since 2020) | 24702 |
Cited By | 45242 |
hIndex(all) | 123 |
hIndex(since 2020) | 75 |
i10Index(all) | 460 |
i10Index(since 2020) | 322 |
University Profile Page | University of Michigan |
Research & Interests List
neurology
diabetes
neuropathy
ALS
Alzheimer's disease
Top articles of Eva L. Feldman
Peripheral Immune Profiles Predict ALS Progression in an Age-and Sex-Dependent Manner
Background and ObjectivesAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease whose pathobiology associates with peripheral blood immune cell levels and activation patterns in an age and sex-dependent manner. This study's objective was to identify immune profile associations with ALS progression, whether the associations are age and sex-specific, and whether immune profiles can predict a future disease course.MethodsFlow cytometry immune profiles (a combination of 22 peripheral blood immune markers) were generated for 241 participants with ALS and linked to ALS progression, using progression-free survival, which is a composite combining the revised ALS Functional Rating Scale and survival. Participants were first grouped by immune profiles using unsupervised hierarchical clustering, and clusters were associated with subsequent progression-free survival. Next, individual …
Authors
Benjamin J Murdock,Bangyao Zhao,Kristen D Pawlowski,Joshua P Famie,Caroline E Piecuch,Ian F Webber-Davis,Samuel J Teener,Eva L Feldman,Lili Zhao,Stephen A Goutman
Journal
Neurology: Neuroimmunology & Neuroinflammation
Published Date
2024/4/16
Gender Differences in Faculty Perceptions of Mentorship and Sponsorship
Despite increasing awareness of the importance of mentorship and sponsorship in academic medicine and gender differences in their receipt during early career stages, knowledge is lacking regarding the experiences and perceptions of senior faculty. 1-3 We surveyed a national cohort of midto senior-career faculty about their experiences with receiving and providing mentorship and sponsorship and their perceptions regarding the costs and benefits of these relationships.
Authors
Christina M Cutter,Kent A Griffith,Isis H Settles,Abigail J Stewart,Eve A Kerr,Eva L Feldman,Reshma Jagsi
Journal
JAMA Network Open
Published Date
2024/2/5
Professional Experiences and Career Trajectories of Mid-to Senior-Career Women Clinician-Scientists: A Qualitative Study
ImportanceDespite increasing evidence and recognition of persistent gender disparities in academic medicine, qualitative data detailing the association of gender-based experiences with career progression remain sparse, particularly at the mid- to senior-career stage.ObjectiveTo investigate the role gender has played in everyday professional experiences of mid- to senior-career women clinician-scientists and their perceptions of gender-related barriers experienced across their careers.Design, Setting, and ParticipantsIn this qualitative study, a total of 60 of 159 invited clinician-scientists who received National Institutes of Health K08 or K23 awards between 2006 and 2009 and responded to a survey in 2021 agreed to participate. Invitees were selected using random, purposive sampling to support sample heterogeneity. Semistructured in-depth interviews were conducted January to May 2022. For this study …
Authors
Lauren A Szczygiel,Amanda K Greene,Christina M Cutter,Rochelle D Jones,Eva L Feldman,Kelly C Paradis,Isis H Settles,Kanakadurga Singer,Nancy D Spector,Abigail J Stewart,Peter A Ubel,Reshma Jagsi
Journal
JAMA Network Open
Published Date
2024/4/1
Neuropathic Pain With and Without Diabetic Peripheral Neuropathy in Type 1 Diabetes
OBJECTIVE Diabetic peripheral neuropathy (DPN) is common; however, the features and burden of neuropathic pain (NP) in type 1 diabetes (T1D) are poorly understood. We evaluated the incidence of first occurrence, annual prevalence, remission, and risk factors for NP during long-term follow-up of participants with T1D. RESEARCH DESIGN AND METHODS The Michigan Neuropathy Screening Instrument (MNSI) was administered annually (1994–2020) for 1,324 participants in the Epidemiology of Diabetes Interventions and Complications (EDIC) study. NP with clinical signs of DPN (NP DPN+) was defined according to self-reported NP plus an examination score >2, while NP without clinical signs of DPN (NP DPN−) was defined according to self-reported NP and an examination score ≤2. RESULTS At EDIC year 1, median age for participants was 36 …
Authors
Barbara H Braffett,Laure El Ghormli,James W Albers,Eva L Feldman,William H Herman,Rose A Gubitosi-Klug,Catherine L Martin,Trevor J Orchard,Neil H White,John M Lachin,Bruce A Perkins,Rodica Pop-Busui,DCCT/EDIC Research Group
Journal
Diabetes Care
Published Date
2024/2/1
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Background: Environmental exposures impact amyotrophic lateral sclerosis (ALS) risk and progression, a fatal and progressive neurodegenerative disease. Better characterization of these exposures is needed to decrease disease burden. Objective: To identify exposures in the residential setting that associate with ALS risk, survival, and onset segment. Methods: ALS and control participants recruited from University of Michigan completed a survey that ascertained exposure risks in the residential setting. ALS risk was assessed using logistic regression models followed by latent profile analysis to consider exposure profiles. A case-only analysis considered the contribution of the residential exposure variables via a Cox proportional hazards model for survival outcomes and multinomial logistic regression for onset segment, a polytomous outcome. Results: This study included 367 ALS and 255 control participants …
Authors
Stephen A Goutman,Jonathan Boss,Dae Gyu Jang,Caroline Piecuch,Hasan Farid,Madeleine Batra,Bhramar Mukherjee,Eva L Feldman,Stuart A Batterman
Journal
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Published Date
2024/4/1
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex, fatal neurodegenerative disease. Disease pathophysiology is incompletely understood but evidence suggests gut dysbiosis occurs in ALS, linked to impaired gastrointestinal integrity, immune system dysregulation and altered metabolism. Gut microbiome and plasma metabolome have been separately investigated in ALS, but little is known about gut microbe-plasma metabolite correlations, which could identify robust disease biomarkers and potentially shed mechanistic insight. Here, gut microbiome changes were longitudinally profiled in ALS and correlated to plasma metabolome. Gut microbial structure at the phylum level differed in ALS versus control participants, with differential abundance of several distinct genera. Unsupervised clustering of microbe and metabolite levels identified modules, which differed significantly in ALS versus control participants …
Authors
Kai Guo,Claudia Figueroa-Romero,Mohamed H Noureldein,Benjamin J Murdock,Masha G Savelieff,Junguk Hur,Stephen A Goutman,Eva L Feldman
Journal
Brain
Published Date
2024/2
Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort
BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal, progressive neurogenerative disease caused by combined genetic susceptibilities and environmental exposures. Identifying and validating these exposures are of paramount importance to modify disease risk. We previously reported that persistent organic pollutants (POPs) associate with ALS risk and survival and aimed to replicate these findings in a new cohort.MethodParticipants with and without ALS recruited in Michigan provided plasma samples for POPs analysis by isotope dilution with triple quadrupole mass spectrometry. ORs for risk models and hazard ratios for survival models were calculated for individual POPs. POP mixtures were represented by environmental risk scores (ERS), a summation of total exposures, to evaluate the association with risk (ERSrisk) and survival (ERSsurvival).ResultsSamples from 164 ALS and 105 control participants …
Authors
Stephen A Goutman,Jonathan Boss,Dae-Gyu Jang,Bhramar Mukherjee,Rudy J Richardson,Stuart Batterman,Eva L Feldman
Journal
Journal of Neurology, Neurosurgery & Psychiatry
Published Date
2024/3/1
Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy
Peripheral neuropathy (PN) is a severe and frequent complication of obesity, prediabetes, and type 2 diabetes characterized by progressive distal-to-proximal peripheral nerve degeneration. However, a comprehensive understanding of the mechanisms underlying PN, and whether these mechanisms change during PN progression, is currently lacking. Here, gene expression data were obtained from distal (sciatic nerve; SCN) and proximal (dorsal root ganglia; DRG) injury sites of a high-fat diet (HFD)-induced mouse model of obesity/prediabetes at early and late disease stages. Self-organizing map and differentially expressed gene analyses followed by pathway enrichment analysis identified genes and pathways altered across disease stage and injury site. Pathways related to immune response, inflammation, and glucose and lipid metabolism were consistently dysregulated with HFD-induced PN, irrespective of …
Authors
Stéphanie A Eid,Sarah E Elzinga,Kai Guo,Lucy M Hinder,John M Hayes,Crystal M Pacut,Emily J Koubek,Junguk Hur,Eva L Feldman
Journal
Translational Research
Published Date
2024/8/1
Professor FAQs
What is Eva L. Feldman's h-index at University of Michigan?
The h-index of Eva L. Feldman has been 75 since 2020 and 123 in total.
What are Eva L. Feldman's top articles?
The articles with the titles of
Peripheral Immune Profiles Predict ALS Progression in an Age-and Sex-Dependent Manner
Gender Differences in Faculty Perceptions of Mentorship and Sponsorship
Professional Experiences and Career Trajectories of Mid-to Senior-Career Women Clinician-Scientists: A Qualitative Study
Neuropathic Pain With and Without Diabetic Peripheral Neuropathy in Type 1 Diabetes
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis
Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort
Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy
...
are the top articles of Eva L. Feldman at University of Michigan.
What are Eva L. Feldman's research interests?
The research interests of Eva L. Feldman are: neurology, diabetes, neuropathy, ALS, Alzheimer's disease
What is Eva L. Feldman's total number of citations?
Eva L. Feldman has 61,738 citations in total.
What are the co-authors of Eva L. Feldman?
The co-authors of Eva L. Feldman are Brian Callaghan, Nicholas Boulis, Stephen A Goutman.