Peter A. Wijeratne

Peter A. Wijeratne

University College London

H-index: 190

Europe-United Kingdom

Peter A. Wijeratne Information

University

University College London

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Citations(all)

152826

Citations(since 2020)

51547

Cited By

117226

hIndex(all)

190

hIndex(since 2020)

110

i10Index(all)

623

i10Index(since 2020)

512

Email

University Profile Page

University College London

Peter A. Wijeratne Skills & Research Interests

Probabilistic modelling

Top articles of Peter A. Wijeratne

Characterizing developing executive functions in the first 1000 days in South Africa and Malawi: The Khula Study

Authors

Michal R Zieff,Marlie Miles,Emmie Mbale,Emma Eastman,Lorna Ginnell,Steven CR Williams,Derek K Jones,Daniel C Alexander,Peter A Wijeratne,Laurel J Gabard-Durnam,Vanja Klepac-Ceraj,Kevin S Bonham,Nicolò Pini,Ayesha Sania,Maristella Lucchini,Sean Deoni,William P Fifer,Melissa Gladstone,Dima Amso,Kirsten A Donald

Journal

Wellcome Open Research

Published Date

2024/3/20

The term ‘executive functions’ (EFs) refers to a set of skills that support flexible control over thought and action. Classic EFs (working memory, inhibitory control, and cognitive flexibility) do not show measurable stable function until after the third year of life and continue to develop into early adulthood. However, even at the earliest ages, these EFs are shown to have value for predicting school readiness and academic achievement. They continue to have predictive value for success, mental health, and general well-being across the lifespan including in ageing populations. As such, understanding the developing brain and cognitive developmental dynamics that set the stage for the development of EFs, in the first three years of life, is crucial for developing programming that supports healthy EFs development. The goal of this manuscript is to describe the goals, hypotheses, participant populations, and methodology of the Khula Study. Khula is a multi-modal multi-site longitudinal birth cohort study designed to characterise emerging EFs in the first 1000 days of life in global majority settings. Most research to date has been conducted in highincome countries rather than low- and middle-income countries that comprise most of the world’s child population. We assert that understanding and supporting EF development has global importance, but this must be done with the understanding that EFs are skills that develop within the context of adaptation to one’s environment. As such, the Khula Study aims to understand which EF influences are common across cultures but also which are culture specific. We will address these questions by incorporating data …

Investigating the Role of Bilateral Symmetry for Inpainting Brain MRI

Authors

Sergey Kuznetsov,Sanduni Pinnawala,Peter A Wijeratne,Ivor JA Simpson

Published Date

2024/2/13

Inpainting has recently emerged as a valuable and interesting technology to employ in the analysis of medical imaging data, in particular brain MRI. A wide variety of methodologies for inpainting MRI have been proposed and demonstrated on tasks including anomaly detection.In this work we investigate the statistical relationship between inpainted brain structures and the amount of subject-specific conditioning information, i.e. the other areas of the image that are masked. In particular, we analyse the distribution of inpainting results when masking additional regions of the image, specifically the contra-lateral structure. This allows us to elucidate where in the brain the model is drawing information from, and in particular, what is the importance of hemispherical symmetry? Our experiments interrogate a diffusion inpainting model through analysing the inpainting of subcortical brain structures based on intensity and estimated area change. We demonstrate that some structures show a strong influence of symmetry in the conditioning of the inpainting process.

Distinct spatiotemporal atrophy patterns in corticobasal syndrome are associated with different underlying pathologies

Authors

William J Scotton,Cameron Shand,Emily Todd,Martina Bocchetta,David M Cash,Lawren VandeVrede,Hilary W Heuer,Alexandra L Young,Neil P Oxtoby,Daniel C Alexander,James B Rowe,Huw Morris,Adam L Boxer,Jonathan D Rohrer,Peter A Wijeratne

Journal

medRxiv

Published Date

2024

Objective To identify imaging subtypes of the cortico-basal syndrome (CBS) based solely on a data-driven assessment of MRI atrophy patterns, and investigate whether these subtypes provide information on the underlying pathology. Methods We applied Subtype and Stage Inference (SuStaIn), a machine learning algorithm that identifies groups of individuals with distinct biomarker progression patterns, to a large cohort of 135 CBS cases (52 had a pathological or biomarker defined diagnosis) and 252 controls. The model was fit using volumetric features extracted from baseline T1-weighted MRI scans and validated using follow-up MRI. We compared the clinical phenotypes of each subtype and investigated whether there were differences in associated pathology between the subtypes. Results SuStaIn identified two subtypes with distinct sequences of atrophy progression; four-repeat-tauopathy confirmed cases were most commonly assigned to the Subcortical subtype (83% of CBS-PSP and 75% of CBS-CBD), while CBS-AD was most commonly assigned to the Fronto-parieto-occipital subtype (81% of CBS-AD). Subtype assignment was stable at follow-up (98% of cases), and individuals consistently progressed to higher stages (100% stayed at the same stage or progressed), supporting the model ability to stage progression. Interpretation By jointly modelling disease stage and subtype, we provide data-driven evidence for at least two distinct and longitudinally stable spatiotemporal subtypes of atrophy in CBS that are associated with different underlying pathologies. In the absence of sensitive and specific biomarkers, accurately subtyping …

The temporal event-based model: Learning event timelines in progressive diseases

Authors

Peter A Wijeratne,Arman Eshaghi,William J Scotton,Maitrei Kohli,Leon Aksman,Neil P Oxtoby,Dorian Pustina,John H Warner,Jane S Paulsen,Rachael I Scahill,Cristina Sampaio,Sarah J Tabrizi,Daniel C Alexander,Alzheimer’s Disease Neuroimaging Initiative (ADNI),the Open Access Series of Imaging Studies (OASIS),the PREDICT-HD study,and the TRACK-HD study

Journal

Imaging Neuroscience

Published Date

2023/8/21

Timelines of events, such as symptom appearance or a change in biomarker value, provide powerful signatures that characterise progressive diseases. Understanding and predicting the timing of events is important for clinical trials targeting individuals early in the disease course when putative treatments are likely to have the strongest effect. However, previous models of disease progression cannot estimate the time between events and provide only an ordering in which they change. Here, we introduce the temporal event-based model (TEBM), a new probabilistic model for inferring timelines of biomarker events from sparse and irregularly sampled datasets. We demonstrate the power of the TEBM in two neurodegenerative conditions: Alzheimer’s disease (AD) and Huntington’s disease (HD). In both diseases, the TEBM not only recapitulates current …

Subtype and stage inference with timescales

Authors

Alexandra L Young,Leon M Aksman,Daniel C Alexander,Peter A Wijeratne,Alzheimer’s Disease Neuroimaging Initiative

Published Date

2023/6/8

Neurodegenerative conditions typically have highly heterogeneous trajectories, with variability in both the spatial and temporal progression of neurological changes. Disentangling the variability in spatiotemporal progression patterns offers major benefits for patient stratification and disease understanding but is a complex methodological challenge. Here we present Temporal Subtype and Stage Inference (T-SuStaIn), a technique that uniquely integrates distinct ideas from unsupervised learning: disease progression modelling, clustering, and hidden Markov modelling. We formulate T-SuStaIn mathematically and devise an algorithm for inferring the model parameters and uncertainty. We demonstrate that the combination of disease progression modelling, clustering, and hidden Markov modelling uniquely enables the discovery of subtypes distinguished not just by ordering of abnormality accumulation, but also …

Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning

Authors

William J Scotton,Cameron Shand,Emily Todd,Martina Bocchetta,David M Cash,Lawren VandeVrede,Hilary Heuer,Alexandra L Young,Neil Oxtoby,Daniel C Alexander,James B Rowe,Huw R Morris,Adam L Boxer,Jonathan D Rohrer,Peter A Wijeratne

Journal

Brain communications

Published Date

2023/4/1

To better understand the pathological and phenotypic heterogeneity of progressive supranuclear palsy and the links between the two, we applied a novel unsupervised machine learning algorithm (Subtype and Stage Inference) to the largest MRI data set to date of people with clinically diagnosed progressive supranuclear palsy (including progressive supranuclear palsy–Richardson and variant progressive supranuclear palsy syndromes). Our cohort is comprised of 426 progressive supranuclear palsy cases, of which 367 had at least one follow-up scan, and 290 controls. Of the progressive supranuclear palsy cases, 357 were clinically diagnosed with progressive supranuclear palsy–Richardson, 52 with a progressive supranuclear palsy–cortical variant (progressive supranuclear palsy–frontal, progressive supranuclear palsy–speech/language, or progressive supranuclear palsy–corticobasal), and 17 …

A data-driven study of Alzheimer's disease related amyloid and tau pathology progression

Authors

Leon M Aksman,Neil P Oxtoby,Marzia A Scelsi,Peter A Wijeratne,Alexandra L Young,Isadora Lopes Alves,Lyduine E Collij,Jacob W Vogel,Frederik Barkhof,Daniel C Alexander,Andre Altmann,ADNI

Journal

Brain

Published Date

2023/12

Amyloid-β is thought to facilitate the spread of tau throughout the neocortex in Alzheimer's disease, though how this occurs is not well understood. This is because of the spatial discordance between amyloid-β, which accumulates in the neocortex, and tau, which accumulates in the medial temporal lobe during ageing. There is evidence that in some cases amyloid-β-independent tau spreads beyond the medial temporal lobe where it may interact with neocortical amyloid-β. This suggests that there may be multiple distinct spatiotemporal subtypes of Alzheimer's-related protein aggregation, with potentially different demographic and genetic risk profiles. We investigated this hypothesis, applying data-driven disease progression subtyping models to post-mortem neuropathology and in vivo PET-based measures from two large observational studies: the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the …

BRAIN COMMUNICATIONS

Authors

Hanna Leister,Felix F Krause,Beatriz Gil,Ruslan Prus,Inna Prus,Anne Hellhund-Zingel,Meghma Mitra,Rogerio Da Rosa Gerbatin,Norman Delanty,Alan Beausang,Francesca M Brett,Michael A Farrell,Jane Cryan,Donncha F O’Brien,David C Henshall,Frederik Helmprobst,Axel Pagenstecher,Ulrich Steinhoff,Alexander Visekruna,Tobias Engel

Published Date

2024

The proteasome is an evolutionary conserved protease that recognizes and degrades damaged and misfolded proteins via proteolysis. 1 The 26S proteasome consists of the 19S regulatory subunit and the core proteolytic enzyme, 20S proteasome. 2 The proteasome-dependent degradation of tagged, polyubiquitinated proteins is an essential cellular pathway that regulates a wide range of cellular processes, including cell cycle, apoptosis, oxidative stress, cell proliferation and activation of transcription factors such as NF-κB. 3 In contrast to the ubiquitously expressed constitutive proteasome, which is the crucial cellular protease containing the three catalytic subunits, β1, β2 and β5, the immunoproteasome is induced via de novo assembly upon stimulation of cells by Type I and Type II interferons. The incorporation of newly synthetized catalytic subunits, β1i/LMP2, β2i/MECL-1 and β5i/LMP7, is an essential cellular strategy to eliminate intracellular bacteria and viruses. 4 The immunoproteasome exhibits an altered proteolytic function that is required for optimal generation of epitopes for presentation on major histocompatibility complex Class I (MHC-I) molecules in infected cells. It was shown that immunoproteasomes transiently replace constitutive proteasomes during an anti-bacterial (Listeria monocytogenes) and anti-viral (lymphocytic choriomeningitis virus) immune response in the liver. 5 Apart from their function in the generation of a broad pool of MHC-I ligands and in triggering effective activation of cytotoxic T lymphocytes, immunoproteasomes appear to act as a pro-inflammatory factor that is involved in tissue inflammation and damage, as …

Predicting Huntington's disease state with ensemble learning & sMRI: more than just the striatum

Authors

Maitrei Kohli,Dorian Pustina,John H Warner,Daniel C Alexander,Rachael I Scahill,Sarah J Tabrizi,Cristina Sampaio,Peter A Wijeratne

Journal

medRxiv

Published Date

2023

Developing effective treatments for Huntington's disease (HD) requires reliable markers of disease progression. Striatal atrophy has been the hallmark of HD progression, but volumetric anomalies are also found in other brain regions. Little is known about the potential increase in predictive biomarking accuracy when volumetric scores from multiple brain regions are combined to predict the HD status of individual participants. We used cross-sectional structural MRI data from 184 HD gene-positive participants to a) test a novel ensemble machine learning model in classifying participants in one of four HD progression states (PreHD A; PreHD B; HD1; HD2), and (b) identify the brain regions that carry HD biomarking signal from 15 regions. We used 5-fold cross validation and backward feature elimination to find the optimal predictors and investigated the stability of the findings through repeated analyses. The ensemble predictive model systematically matched or outperformed the accuracy of nine standard machine learning models, reaching 55.3%±6.1 balanced accuracy in 4-group classification. The accuracy was higher for binary classifications (PreHD vs HD: 83.3%± 6.3; PreHD A vs PreHD B: 76.7%± 8.0; PreHD B vs HD1: 75.9% ± 8.5; HD1 vs HD2: 70.9%±9.4). Striatal structures (caudate and putamen) were systematically found to be top predictors. However, the accuracy increased substantially when we included other regions in the model (e.g., occipital cortex, lateral ventricles, cingulate, temporal lobe). Optimal models frequently included 2-7 brain regions from different areas. Overall, the accuracy of classifications remained stable across …

Correction to: Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning

Authors

William J Scotton,Cameron Shand,Emily Todd,Martina Bocchetta,David M Cash,Lawren VandeVrede,Hilary Heuer,Alexandra L Young,Neil Oxtoby,Daniel C Alexander,James B Rowe,Huw R Morris,Adam L Boxer,Jonathan D Rohrer,Peter A Wijeratne

Journal

Brain Communications

Published Date

2023/11/27

This is a correction to: William J Scotton, Cameron Shand, Emily Todd, Martina Bocchetta, David M Cash, Lawren VandeVrede, Hilary Heuer, PROSPECT Consortium, 4RTNI Consortium, Alexandra L Young, Neil Oxtoby, Daniel C Alexander, James B Rowe, Huw R Morris, Adam L Boxer, Jonathan D Rohrer, Peter A Wijeratne, Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning, Brain Communications, Volume 5, Issue 2, 2023, https://doi.org/10.1093/braincomms/fcad048

Temporal progression patterns of brain atrophy in corticobasal syndrome and progressive supranuclear palsy revealed by Subtype and Stage Inference (SuStaIn)

Authors

Yuya Saito,Koji Kamagata,Peter A Wijeratne,Christina Andica,Wataru Uchida,Kaito Takabayashi,Shohei Fujita,Toshiaki Akashi,Akihiko Wada,Keigo Shimoji,Masaaki Hori,Yoshitaka Masutani,Daniel C Alexander,Shigeki Aoki

Journal

Frontiers in Neurology

Published Date

2022/2/25

Differentiating corticobasal degeneration presenting with corticobasal syndrome (CBD-CBS) from progressive supranuclear palsy with Richardson's syndrome (PSP-RS), particularly in early stages, is often challenging because the neurodegenerative conditions closely overlap in terms of clinical presentation and pathology. Although volumetry using brain magnetic resonance imaging (MRI) has been studied in patients with CBS and PSP-RS, studies assessing the progression of brain atrophy are limited. Therefore, we aimed to reveal the difference in the temporal progression patterns of brain atrophy between patients with CBS and those with PSP-RS purely based on cross-sectional data using Subtype and Stage Inference (SuStaIn)—a novel, unsupervised machine learning technique that integrates clustering and disease progression modeling. We applied SuStaIn to the cross-sectional regional brain volumes of 25 patients with CBS, 39 patients with typical PSP-RS, and 50 healthy controls to estimate the two disease subtypes and trajectories of CBS and PSP-RS, which have distinct atrophy patterns. The progression model and classification accuracy of CBS and PSP-RS were compared with those of previous studies to evaluate the performance of SuStaIn. SuStaIn identified distinct temporal progression patterns of brain atrophy for CBS and PSP-RS, which were largely consistent with previous evidence, with high reproducibility (99.7%) under cross-validation. We classified these diseases with high accuracy (0.875) and sensitivity (0.680 and 1.000, respectively) based on cross-sectional structural brain MRI data; the accuracy was higher than …

Emulating the impact of additional proton–proton interactions in the ATLAS simulation by presampling sets of inelastic Monte Carlo events

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,NL Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,AC Abusleme Hoffman,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,Chiara Arcangeletti,ATH Arce,Jean-Francois Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli,WK Balunas,J Balz,E Banas,M Bandieramonte

Journal

Computing and Software for Big Science

Published Date

2022/12

The accurate simulation of additional interactions at the ATLAS experiment for the analysis of proton–proton collisions delivered by the Large Hadron Collider presents a significant challenge to the computing resources. During the LHC Run 2 (2015–2018), there were up to 70 inelastic interactions per bunch crossing, which need to be accounted for in Monte Carlo (MC) production. In this document, a new method to account for these additional interactions in the simulation chain is described. Instead of sampling the inelastic interactions and adding their energy deposits to a hard-scatter interaction one-by-one, the inelastic interactions are presampled, independent of the hard scatter, and stored as combined events. Consequently, for each hard-scatter interaction, only one such presampled event needs to be added as part of the simulation chain. For the Run 2 simulation chain, with an average of 35 interactions per …

Predicting personalised risk of disability worsening in multiple sclerosis with machine learning

Authors

Arman Eshaghi,Peter A Wijeratne,Neil P Oxtoby,Douglas L Arnold,Louis Collins,Sridar Narayanan,Charles RG Guttmann,Alan J Thompson,Daniel C Alexander,Frederik Barkhof,Declan Chard,Olga Ciccarelli

Journal

medRxiv

Published Date

2022/2/3

Multiple sclerosis is a heterogeneous disease with an unpredictable course. We applied machine learning to generate individualised risk scores of disability worsening and stratify patients into subgroups with different prognosis.Clinical data and MRI scans from published randomised clinical trials in patients with relapsing-remitting and progressive MS were divided into training (n=5,483) and external validation data sets (n=2,668). We processed brain MRI scans to obtain 18 measures for lobar grey matter, deep grey matter and lesion volumes, and T1-/T2-weighted ratio of the normal-appearing white matter regions. We developed a machine learning model, called subpopulation risk stratification (SunRiSe), that combines multi-parametric clinical and MRI data to estimate individualised risk scores and stratify patients into subgroups on the basis of this risk; in particular, we entered MRI measures, the Expanded Disability Status Scale, age and gender to generate risk scores of disability worsening (i.e., the time to confirmed disability worsening). Based on SunRiSe risk scores, high-, medium-, and low-risk subpopulations were defined at study entry. We assessed whether selecting patients at high risk of disability worsening reduces sample size compared to when all risk groups were sampled together.In both the training and external validation data sets, SunRiSe-stratified patients in three groups associated with different levels of risk of disability worsening. In the external validation data set, patients at high risk were mainly progressive MS and had more disability events compared to those at medium-risk (hazard ratio [HR]=1.34, p<0.0001) and low …

Regional left ventricle scar detection from routine cardiac computed tomography angiograms using latent space classification

Authors

Hugh O’Brien,John Whitaker,Mark D O’Neill,Karine Grigoryan,Harminder Gill,Vishal Mehta,Mark K Elliot,Christopher Aldo Rinaldi,Holly Morgan,Divaka Perera,Jonathan Taylor,Ronak Rajani,Kawal Rhode,Steven Niederer

Journal

Computers in Biology and Medicine

Published Date

2022/11/1

Objectives: The aim of this study is to develop an automated method of regional scar detection on clinically standard computed tomography angiography (CTA) using encoder–decoder networks with latent space classification. Background: Localising scar in cardiac patients can assist in diagnosis and guide interventions. Magnetic resonance imaging (MRI) with late gadolinium enhancement (LGE) is the clinical gold standard for scar imaging; however, it is commonly contraindicated. CTA is an alternative imaging modality that has fewer contraindications and is widely used as a first-line imaging modality of cardiac applications. Methods: A dataset of 79 patients with both clinically indicated MRI LGE and subsequent CTA scans was used to train and validate networks to classify septal and lateral scar presence within short axis left ventricle slices. Two designs of encoder–decoder networks were compared, with one …

Quantifying morphological airway damage in idiopathic pulmonary fibrosis

Authors

A Pakzad,WK Cheung,K Quan,N Mogulkoc,CH Van Moorsel,BJ Bartholmai,HW Van Es,A Ezircan,F Van Beek,M Veltkamp,R Karwoski,T Peikert,RD Clay,F Foley,C Braun,R Savas,C Sudre,T Doel,DC Alexander,P Wijeratne,D Hawkes,Y Hu,JR Hurst,J Jacob

Published Date

2022/9/4

Aims and Objectives: To investigate differences in airway morphology on computed tomography (CT) imaging in patients with idiopathic pulmonary fibrosis (IPF) compared to healthy subjects.Methods: Airway segmentations were derived from CT scans in 14 IPF patients and 14 healthy subjects and examined using AirQuant, an open-source software tool. Diameters and lengths of airway segments (representing an airway between branching or endpoints) were measured. These were used to derive the median intertapering (change in average segment diameter compared to parent) and tortuosity (ratio of actual length to Euclidean length) for all central (generations 2-6) and distal (beyond 6) airway segments in the upper and lower lobes. Medians were compared between IPF and healthy using the Mann-Whitney-U test.Results: IPF patients: mean age=63 years; 93% male; mean DLco=49%. Healthy subjects had …

BRAIN COMMUNICATIONS AIN COMMUNICATIONS

Authors

LA Benjamin,E Lim,M Sokolska,J Markus,T Zaletel,V Aggarwal,R Luder,E Sanchez,K Brown,R Sofat,A Singh,C Houlihan,E Nastouli,N Losseff,DJ Werring,MM Brown,JC Mason,RJ Simister,HR Jäger

Published Date

2022

Cryptogenic stroke not caused by large artery atherosclerosis, cardioembolism or small vessel occlusion, is common and accounts for∼ one-third of ischaemic stroke presentations. 1 Very little is known to what extent uncommon but potentially treatable aetiologies, such as medium–large vessel intracranial vasculitis, contribute to this substantial patient group but, the wider availability of arterial imaging at hospital presentation is increasingly identifying patients with intracranial artery pathology without a cause. Vasculitis is a term reserved for when there is histopathological confirmation with characteristic granulomatous, lymphocytic or necrotising vessel inflammation alongside vessel wall damage. In the absence of histology, we use the term vasculopathy. 2 The causes of medium–large vessel intracranial vasculitis are multifactorial, including infection, autoimmune, neoplastic, metabolic and genetic conditions. 3

E13 Predicting Huntington’s disease state using structural MRI: it’s more than just the striatum

Authors

Maitrei Kohli,Dorian Pustina,John H Warner,Daniel C Alexander,Rachael I Scahill,Sarah J Tabrizi,Peter A Wijeratne

Published Date

2022/9/1

Background Volumetric measures derived from structural MRI (sMRI) enable identification of Huntington’s disease (HD)-related brain alterations. Stacked machine learning (ML) models allow data-driven patient-specific predictions of disease state. Quantifying feature importance aids interpretation of model outcomes by identifying which regions carry most discriminative information.Aims We aimed to (a) classify HD state using stacked ML model and features obtained from sMRI, and (b) identify which features are most discriminative for each HD state. We performed fine-grained (PreHD-A; PreHD-B; HD1; HD2), and binary (PreHD-A vs PreHD-B; PreHD-B vs HD1; and HD1 vs HD2) classification.Methods We trained and evaluated our stacked ML model using baseline cross-sectional sMRI data from 184 HD gene-positive participants from the TRACK-HD dataset. Performance was assessed using repeated stratified …

A data-driven model of brain volume changes in progressive supranuclear palsy

Authors

WJ Scotton,M Bocchetta,E Todd,DM Cash,N Oxtoby,L VandeVrede,H Heuer,PROSPECT Consortium,4RTNI Consortium,DC Alexander,JB Rowe,HR Morris,A Boxer,JD Rohrer,PA Wijeratne

Journal

Brain communications

Published Date

2022/6/1

The most common clinical phenotype of progressive supranuclear palsy is Richardson syndrome, characterized by levodopa unresponsive symmetric parkinsonism, with a vertical supranuclear gaze palsy, early falls and cognitive impairment. There is currently no detailed understanding of the full sequence of disease pathophysiology in progressive supranuclear palsy. Determining the sequence of brain atrophy in progressive supranuclear palsy could provide important insights into the mechanisms of disease progression, as well as guide patient stratification and monitoring for clinical trials. We used a probabilistic event-based model applied to cross-sectional structural MRI scans in a large international cohort, to determine the sequence of brain atrophy in clinically diagnosed progressive supranuclear palsy Richardson syndrome. A total of 341 people with Richardson syndrome (of whom 255 had 12-month …

Revealing the timeline of structural MRI changes in premanifest to manifest Huntington disease

Authors

Peter A Wijeratne,Sara Garbarino,Sarah Gregory,Eileanoir B Johnson,Rachael I Scahill,Jane S Paulsen,Sarah J Tabrizi,Marco Lorenzi,Daniel C Alexander

Journal

Neurology: Genetics

Published Date

2021/10/12

Background and ObjectivesLongitudinal measurements of brain atrophy using structural MRI (sMRI) can provide powerful markers for tracking disease progression in neurodegenerative diseases. In this study, we use a disease progression model to learn individual-level disease times and hence reveal a new timeline of sMRI changes in Huntington disease (HD).MethodsWe use data from the 2 largest cohort imaging studies in HD—284 participants from TRACK-HD (100 control, 104 premanifest, and 80 manifest) and 159 participants from PREDICT-HD (36 control and 128 premanifest)—to train and test the model. We longitudinally register T1-weighted sMRI scans from 3 consecutive time points to reduce intraindividual variability and calculate regional brain volumes using an automated segmentation tool with rigorous manual quality control.ResultsOur model reveals, for the first time, the relative magnitude and …

Determination of the parton distribution functions of the proton from ATLAS measurements of differential W±and Z boson production in association with jets

Authors

Georges Aad,B Abbott,DC Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,SH Abidi,Asmaa Aboulhorma,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,AC Abusleme Hoffman,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,SV Addepalli,Jahred Adelman,Aytul Adiguzel,S Adorni,Tim Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,J Agarwala,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,I Aizenberg,M Akbiyik,TPA Åkesson,AV Akimov,K Al Khoury,GL Alberghi,J Albert,P Albicocco,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,KR Amos,CS Amrouche,V Ananiev,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,C Arcangeletti,ATH Arce,E Arena,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,S Auricchio,VA Austrup,G Avner,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,A Bachiu,F Backman,A Badea,P Bagnaia,M Bahmani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin

Journal

The European Physical Journal C

Published Date

2022/5/13

This paper presents an analysis at next-to-next-to-leading order in the theory of quantum chromodynamics for the determination of a new set of proton parton distribution functions using diverse measurements in pp collisions at , 8 and 13 TeV, performed by the ATLAS experiment at the Large Hadron Collider, together with deep inelastic scattering data from ep collisions at the HERA collider. The ATLAS data sets considered are differential cross-section measurements of inclusive and boson production, and Z boson production in association with jets, production, inclusive jet production and direct photon production. In the analysis, particular attention is paid to the correlation of systematic uncertainties within and between the various ATLAS data sets and to the impact of model, theoretical and parameterisation uncertainties. The resulting set of parton distribution functions is called ATLASpdf21.

Ordinal SuStaIn: subtype and stage inference for clinical scores, visual ratings, and other ordinal data

Authors

Alexandra L Young,Jacob W Vogel,Leon M Aksman,Peter A Wijeratne,Arman Eshaghi,Neil P Oxtoby,Steven CR Williams,Daniel C Alexander,Alzheimer’s Disease Neuroimaging Initiative

Journal

Frontiers in artificial intelligence

Published Date

2021/8/12

Subtype and Stage Inference (SuStaIn) is an unsupervised learning algorithm that uniquely enables the identification of subgroups of individuals with distinct pseudo-temporal disease progression patterns from cross-sectional datasets. SuStaIn has been used to identify data-driven subgroups and perform patient stratification in neurodegenerative diseases and in lung diseases from continuous biomarker measurements predominantly obtained from imaging. However, the SuStaIn algorithm is not currently applicable to discrete ordinal data, such as visual ratings of images, neuropathological ratings, and clinical and neuropsychological test scores, restricting the applicability of SuStaIn to a narrower range of settings. Here we propose ‘Ordinal SuStaIn’, an ordinal version of the SuStaIn algorithm that uses a scored events model of disease progression to enable the application of SuStaIn to ordinal data. We demonstrate the validity of Ordinal SuStaIn by benchmarking the performance of the algorithm on simulated data. We further demonstrate that Ordinal SuStaIn out-performs the existing continuous version of SuStaIn (Z-score SuStaIn) on discrete scored data, providing much more accurate subtype progression patterns, better subtyping and staging of individuals, and accurate uncertainty estimates. We then apply Ordinal SuStaIn to six different sub-scales of the Clinical Dementia Rating scale (CDR) using data from the Alzheimer’s disease Neuroimaging Initiative (ADNI) study to identify individuals with distinct patterns of functional decline. Using data from 819 ADNI1 participants we identified three distinct CDR subtype progression patterns …

Differential cross-section measurements for the electroweak production of dijets in association with a Z boson in proton–proton collisions at ATLAS

Authors

Atlas Collaboration

Published Date

2021

Differential cross-section measurements are presented for the electroweak production of two jets in association with a Z boson. These measurements are sensitive to the vector-boson fusion production mechanism and provide a fundamental test of the gauge structure of the Standard Model. The analysis is performed using proton–proton collision data collected by ATLAS at

Measurements of Higgs bosons decaying to bottom quarks from vector boson fusion production with the ATLAS experiment at

Authors

ATLAS Collaboration atlas. publications@ cern. ch,G Aad,Brad Abbott,DC Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,SH Abidi,OS AbouZeid,NL Abraham,H Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,T Asawatavonvanich,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli,WK Balunas,J Balz,E Banas

Journal

The European Physical Journal C

Published Date

2021/6

The paper presents a measurement of the Standard Model Higgs Boson decaying to b-quark pairs in the vector boson fusion (VBF) production mode. A sample corresponding to 126  of proton–proton collision data, collected with the ATLAS experiment at the Large Hadron Collider, is analyzed utilizing an adversarial neural network for event classification. The signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model for VBF Higgs production, is measured to be , corresponding to an observed (expected) significance of 2.6 (2.8) standard deviations from the background only hypothesis. The results are additionally combined with an analysis of Higgs bosons decaying to b-quarks, produced via VBF in association with a photon.

Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndrome

Authors

Rosalyn Hithersay,R Asaad Baksh,Carla M Startin,Peter Wijeratne,Sarah Hamburg,Ben Carter,LonDownS Consortium,Andre Strydom

Journal

Alzheimer's & Dementia

Published Date

2021/4

Introduction People with Down syndrome (DS) typically develop Alzheimer's disease (AD) neuropathology before age 40, but a lack of outcome measures and longitudinal data have impeded their inclusion in randomized controlled trials (RCTs). Methods Cohort study. Event‐based and dose‐response Emax models were fitted to longitudinal cognitive data, to stage AD and determine the earliest ages of decline. Results informed sample size estimations for hypothetical RCTs of disease‐modifying treatments that reduced decline by 35% or 75%. Results Seventy‐five percent of participants progressed or remained stable in the AD staging model; effect sizes varied by age group and tests. Varied treatment effects could be detected with 50‐200 people per arm when using sensitive cognitive outcome measures and targeting recruitment to ages 36 to 45 years. Discussion Efficient RCTs of AD preventative …

Measurement of the jet mass in high transverse momentum Z (→ bb‾) γ production at s= 13TeV using the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,K Abeling,DK Abhayasinghe,SH Abidi,OS AbouZeid,NL Abraham,H Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,S Adachi,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,M Adersberger,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,D Alexandre,T Alexopoulos,A Alfonsi,M Alhroob,B Ali,G Alimonti,J Alison,SP Alkire,C Allaire,BMM Allbrooke,BW Allen,PP Allport,A Aloisio,A Alonso,F Alonso,C Alpigiani,AA Alshehri,M Alvarez Estevez,D Álvarez Piqueras,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,F An,C Anastopoulos,N Andari,T Andeen,CF Anders,JK Anders,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,L Aperio Bella,G Arabidze,JP Araque,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,FA Arduh,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,LJ Armitage,A Armstrong,O Arnaez,H Arnold,A Artamonov,G Artoni,S Artz,S Asai,N Asbah,EM Asimakopoulou,L Asquith,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,K Augsten,G Avolio,R Avramidou,MK Ayoub,AM Azoulay,G Azuelos,MJ Baca,H Bachacou,K Bachas,M Backes,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,M Bajic,C Bakalis,OK Baker,PJ Bakker,D Bakshi Gupta,S Balaji,EM Baldin,P Balek,F Balli

Journal

Physics Letters B

Published Date

2021/1/10

The integrated fiducial cross-section and unfolded differential jet mass spectrum of high transverse momentum Z→ b b‾ decays are measured in Zγ events in proton–proton collisions at s= 13 TeV. The data analysed were collected between 2015 and 2016 with the ATLAS detector at the Large Hadron Collider and correspond to an integrated luminosity of 36.1 fb− 1. Photons are required to have a transverse momentum p T> 175 GeV. The Z→ b b‾ decay is reconstructed using a jet with p T> 200 GeV, found with the anti-k t R= 1.0 jet algorithm, and groomed to remove soft and wide-angle radiation and to mitigate contributions from the underlying event and additional proton–proton collisions. Two different but related measurements are performed using two jet grooming definitions for reconstructing the Z→ b b‾ decay: trimming and soft drop. These algorithms differ in their experimental and phenomenological …

Search for new phenomena in events with two opposite-charge leptons, jets and missing transverse momentum in pp collisions at = 13 TeV with the ATLAS …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

Journal of high energy physics

Published Date

2021/4

The results of a search for direct pair production of top squarks and for dark matter in events with two opposite-charge leptons (electrons or muons), jets and missing transverse momentum are reported, using 139 fb− 1 of integrated luminosity from proton-proton collisions at= 13 TeV, collected by the ATLAS detector at the Large Hadron Collider during Run 2 (2015–2018). This search considers the pair production of top squarks and is sensitive across a wide range of mass differences between the top squark and the lightest neutralino. Additionally, spin-0 mediator dark-matter models are considered, in which the mediator is produced in association with a pair of top quarks. The mediator subsequently decays to a pair of dark-matter particles. No significant excess of events is observed above the Standard Model background, and limits are set at 95% confidence level. The results exclude top squark masses up to …

Measurement of light-by-light scattering and search for axion-like particles with 2.2 nb− 1 of Pb+ Pb data with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,FA Arduh,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,T Asawatavonvanich,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,H Bachacou,K Bachas,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli

Journal

Journal of High Energy Physics

Published Date

2021/3

This paper describes a measurement of light-by-light scattering based on Pb+ Pb collision data recorded by the ATLAS experiment during Run 2 of the LHC. The study uses 2. 2 nb− 1 of integrated luminosity collected in 2015 and 2018 at= 5. 02 TeV. Light-by-light scattering candidates are selected in events with two photons produced exclusively, each with transverse energy> 2. 5 GeV, pseudorapidity| η γ|< 2. 37, diphoton invariant mass m γγ> 5 GeV, and with small diphoton transverse momentum and diphoton acoplanarity. The integrated and differential fiducial cross sections are measured and compared with theoretical predictions. The diphoton invariant mass distribution is used to set limits on the production of axion-like particles. This result provides the most stringent limits to date on axion-like particle production for masses in the range 6–100 GeV. Cross sections above 2 to 70 nb are excluded at the …

Search for dark matter produced in association with a single top quark in  TeV collisions with the ATLAS detector

Authors

ATLAS collaboration

Journal

arXiv preprint arXiv:2211.13138

Published Date

2022/11/23

This paper presents a search for dark matter, , using events with a single top quark and an energetic boson. The analysis is based on proton-proton collision data collected with the ATLAS experiment at 13 TeV during LHC Run 2 (2015-2018), corresponding to an integrated luminosity of 139 fb. The search considers final states with zero or one charged lepton (electron or muon), at least one -jet and large missing transverse momentum. In addition, a result from a previous search considering two-charged-lepton final states is included in the interpretation of the results. The data are found to be in good agreement with the Standard Model predictions and the results are interpreted in terms of 95% confidence-level exclusion limits in the context of a class of dark matter models involving an extended two-Higgs-doublet sector together with a pseudoscalar mediator particle. The search is particularly sensitive to on-shell production of the charged Higgs boson state, , arising from the two-Higgs-doublet mixing, and its semi-invisible decays via the mediator particle, : . Signal models with masses up to 1.5 TeV and masses up to 350 GeV are excluded assuming a tan value of 1. For masses of of 150 (250) GeV, tan values up to 2 are excluded for masses between 200 (400) GeV and 1.5 TeV. Signals with tan values between 20 and 30 are excluded for masses between 500 and 800 GeV.

Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

Journal

Nature physics

Published Date

2021/7

Leptons with essentially the same properties apart from their mass are grouped into three families (or flavours). The number of leptons of each flavour is conserved in interactions, but this is not imposed by fundamental principles. Since the formulation of the standard model of particle physics, the observation of flavour oscillations among neutrinos has shown that lepton flavour is not conserved in neutrino weak interactions. So far, there has been no experimental evidence that this also occurs in interactions between charged leptons. Such an observation would be a sign of undiscovered particles or a yet unknown type of interaction. Here the ATLAS experiment at the Large Hadron Collider at CERN reports a constraint on lepton-flavour-violating effects in weak interactions, searching for Z-boson decays into a τ lepton and another lepton of different flavour with opposite electric charge. The branching fractions for these …

A multi-study model-based evaluation of the sequence of imaging and clinical biomarker changes in Huntington’s disease

Authors

Peter A Wijeratne,Eileanoir B Johnson,Sarah Gregory,Nellie Georgiou-Karistianis,Jane S Paulsen,Rachael I Scahill,Sarah J Tabrizi,Daniel C Alexander

Journal

Frontiers in big Data

Published Date

2021/8/5

Understanding the order and progression of change in biomarkers of neurodegeneration is essential to detect the effects of pharmacological interventions on these biomarkers. In Huntington’s disease (HD), motor, cognitive and MRI biomarkers are currently used in clinical trials of drug efficacy. Here for the first time we use directly compare data from three large observational studies of HD (total N = 532) using a probabilistic event-based model (EBM) to characterise the order in which motor, cognitive and MRI biomarkers become abnormal. We also investigate the impact of the genetic cause of HD, cytosine-adenine-guanine (CAG) repeat length, on progression through these stages. We find that EBM uncovers a broadly consistent order of events across all three studies; that EBM stage reflects clinical stage; and that EBM stage is related to age and genetic burden. Our findings indicate that measures of subcortical and white matter volume become abnormal prior to clinical and cognitive biomarkers. Importantly, CAG repeat length has a large impact on the timing of onset of each stage and progression through the stages, with a longer repeat length resulting in earlier onset and faster progression. Our results can be used to help design clinical trials of treatments for Huntington’s disease, influencing the choice of biomarkers and the recruitment of participants.

Measurements of top-quark pair single- and double-differential cross-sections in the all-hadronic channel in pp collisions at = 13 TeV using the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz,Elzbieta Banas

Journal

Journal of high energy physics

Published Date

2021/1

Differential cross-sections are measured for top-quark pair production in the all-hadronic decay mode, using proton-proton collision events collected by the ATLAS experiment in which all six decay jets are separately resolved. Absolute and normalised single-and double-differential cross-sections are measured at particle and parton level as a function of various kinematic variables. Emphasis is placed on well-measured observables in fully reconstructed final states, as well as on the study of correlations between the top-quark pair system and additional jet radiation identified in the event. The study is performed using data from proton-proton collisions at= 13 TeV collected by the ATLAS detector at CERN’s Large Hadron Collider in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb− 1. The rapidities of the individual top quarks and of the top-quark pair are well modelled by several independent …

Ranking the predictive power of clinical and biological features associated with disease progression in Huntington's disease

Authors

Naghmeh Ghazaleh,Richard Houghton,Giuseppe Palermo,Scott A Schobel,Peter A Wijeratne,Jeffrey D Long

Journal

Frontiers in neurology

Published Date

2021/5/20

Huntington's disease (HD) is characterised by a triad of cognitive, behavioural, and motor symptoms which lead to functional decline and loss of independence. With potential disease-modifying therapies in development, there is interest in accurately measuring HD progression and characterising prognostic variables to improve efficiency of clinical trials. Using the large, prospective Enroll-HD cohort, we investigated the relative contribution and ranking of potential prognostic variables in patients with manifest HD. A random forest regression model was trained to predict change of clinical outcomes based on the variables, which were ranked based on their contribution to the prediction. The highest-ranked variables included novel predictors of progression—being accompanied at clinical visit, cognitive impairment, age at diagnosis and tetrabenazine or antipsychotics use—in addition to established predictors, cytosine adenine guanine (CAG) repeat length and CAG-age product. The novel prognostic variables improved the ability of the model to predict clinical outcomes and may be candidates for statistical control in HD clinical studies.

Search for squarks and gluinos in final states with one isolated lepton, jets, and missing transverse momentum at TeV with the ATLAS detector

Authors

Atlas Collaboration

Journal

arXiv preprint arXiv:2101.01629

Published Date

2021/1/5

The results of a search for gluino and squark pair production with the pairs decaying via the lightest charginos into a final state consisting of two bosons, the lightest neutralinos (), and quarks, are presented. The signal is characterised by the presence of a single charged lepton ( or ) from a boson decay, jets, and missing transverse momentum. The analysis is performed using 139 fb of proton-proton collision data taken at a centre-of-mass energy TeV delivered by the Large Hadron Collider and recorded by the ATLAS experiment. No statistically significant excess of events above the Standard Model expectation is found. Limits are set on the direct production of squarks and gluinos in simplified models. Masses of gluino (squark) up to 2.2 TeV (1.4 TeV) are excluded at 95% confidence level for a light .

Longitudinal Flow Decorrelations in Collisions at with the ATLAS Detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Shunsuke Adachi,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,Azzah Aziz Alshehri,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,Christoph Falk Anders,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,JP Araque,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Sebastian Artz,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz,Elzbieta Banas

Journal

Physical review letters

Published Date

2021/3/24

The first measurement of longitudinal decorrelations of harmonic flow amplitudes v n for n= 2–4 in Xe+ Xe collisions at s N N= 5.44 TeV is obtained using 3 μ b− 1 of data with the ATLAS detector at the LHC. The decorrelation signal for v 3 and v 4 is found to be nearly independent of collision centrality and transverse momentum (p T) requirements on final-state particles, but for v 2 a strong centrality and p T dependence is seen. When compared with the results from Pb+ Pb collisions at s N N= 5.02 TeV, the longitudinal decorrelation signal in midcentral Xe+ Xe collisions is found to be larger for v 2, but smaller for v 3. Current hydrodynamic models reproduce the ratios of the v n measured in Xe+ Xe collisions to those in Pb+ Pb collisions but fail to describe the magnitudes and trends of the ratios of longitudinal flow decorrelations between Xe+ Xe and Pb+ Pb. The results on the system-size dependence provide new …

Search for new phenomena with top quark pairs in final states with one lepton, jets, and missing transverse momentum in pp collisions at = 13 TeV with the …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz

Journal

Journal of high energy physics

Published Date

2021/4

A search for new phenomena with top quark pairs in final states with one isolated electron or muon, multiple jets, and large missing transverse momentum is performed. Signal regions are designed to search for two-, three-, and four-body decays of the directly pair-produced supersymmetric partner of the top quark (stop). Additional signal regions are designed specifically to search for spin-0 mediators that are produced in association with a pair of top quarks and decay into a pair of dark-matter particles. The search is performed using the Large Hadron Collider proton-proton collision dataset at a centre-of-mass energy of= 13 TeV recorded by the ATLAS detector from 2015 to 2018, corresponding to an integrated luminosity of 139 fb− 1. No significant excess above the Standard Model background is observed, and limits at 95% confidence level are set in the stop-neutralino mass plane and as a function of the …

Medium-Induced Modification of -Tagged Charged Particle Yields in Collisions at 5.02 TeV with the ATLAS Detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin

Journal

Physical review letters

Published Date

2021/2/19

The yield of charged particles opposite to a Z boson with large transverse momentum (p T) is measured in 260 pb− 1 of p p and 1.7 nb− 1 of Pb+ Pb collision data at 5.02 TeV per nucleon pair recorded with the ATLAS detector at the Large Hadron Collider. The Z boson tag is used to select hard-scattered partons with specific kinematics, and to observe how their showers are modified as they propagate through the quark-gluon plasma created in Pb+ Pb collisions. Compared with p p collisions, charged-particle yields in Pb+ Pb collisions show significant modifications as a function of charged-particle p T in a way that depends on event centrality and Z boson p T. The data are compared with a variety of theoretical calculations and provide new information about the medium-induced energy loss of partons in a p T regime difficult to measure through other channels.

Learning transition times in event sequences: The temporal event-based model of disease progression

Authors

Peter A Wijeratne,Daniel C Alexander,Alzheimer’s Disease Neuroimaging Initiative

Published Date

2021/6/14

Progressive diseases worsen over time and can be characterised by sequences of events that correspond to changes in observable features of disease progression. Here we connect ideas from two formerly separate methodologies – event-based and hidden Markov modelling – to derive a new generative model of disease progression: the Temporal Event-Based Model (TEBM). TEBM can uniquely infer the most likely group-level sequence and timing of events (natural history) from mixed data types. Moreover, it can infer and predict individual-level trajectories (prognosis) even when data are missing, giving it high clinical utility. Here we derive TEBM and provide an inference scheme based on the expectation maximisation algorithm. We use imaging, clinical and biofluid data from the Alzheimer’s Disease Neuroimaging Initiative to demonstrate the validity and utility of our model. First, we train TEBM to uncover a …

F03 Fine-grained prediction of huntington’s disease progression using a stacked ensemble approach

Authors

Maitrei Kohli,Dorian Pustina,John Warner,Rachael Scahill,Sarah Tabrizi,Daniel Alexander,Peter Wijeratne

Published Date

2021/9/1

Background Classification of individual disease state in Huntington’s disease (HD) is key for stratification of patients in clinical trials. Machine learning (ML) methods can make patient-specific predictions of disease state using clinical data. However, the benefits of using ensemble ML model for HD is currently unknown.Aims We developed a ML framework for predictive classification of individual-level HD disease state. Our framework classifies participants according to (a) binary HD disease state (Premanifest HD (PreHD); manifest HD) and (b) fine-grained disease state (PreHD A; PreHD B; HD1; HD2). The framework comprises an array of standard ML models followed by a Stacked Ensemble (SE) model.Methods We trained and evaluated 6 ML models (the ‘base’ models) using baseline cross-sectional data from 184 HD gene-positive participants from the TRACK-HD dataset, which includes clinical, imaging & …

Measurement of single top-quark production in association with a W boson in the single-lepton channel at with the ATLAS detector

Authors

Georges Aad,Braden Abbott,Dale C Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,S Adachi,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,M Adersberger,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,D Alexandre,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,M Aliev,G Alimonti,J Alison,SP Alkire,C Allaire,BMM Allbrooke,BW Allen,PP Allport,A Aloisio,A Alonso,F Alonso,C Alpigiani,AA Alshehri,M Alvarez Estevez,D Álvarez Piqueras,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,F An,C Anastopoulos,N Andari,T Andeen,CF Anders,JK Anders,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,L Aperio Bella,G Arabidze,JP Araque,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,FA Arduh,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,S Artz,S Asai,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,K Augsten,G Avolio,R Avramidou,MK Ayoub,AM Azoulay,G Azuelos,H Bachacou,K Bachas,M Backes,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,M Bajic,C Bakalis,OK Baker,PJ Bakker,D Bakshi Gupta,S Balaji,EM Baldin

Journal

The European Physical Journal C

Published Date

2021/8

The production cross-section of a top quark in association with a W boson is measured using proton–proton collisions at . The dataset corresponds to an integrated luminosity of , and was collected in 2012 by the ATLAS detector at the Large Hadron Collider at CERN. The analysis is performed in the single-lepton channel. Events are selected by requiring one isolated lepton (electron or muon) and at least three jets. A neural network is trained to separate the tW signal from the dominant background. The cross-section is extracted from a binned profile maximum-likelihood fit to a two-dimensional discriminant built from the neural-network output and the invariant mass of the hadronically decaying W boson. The measured cross-section is , in good agreement with the Standard Model expectation.

Measurement of hadronic event shapes in high-pT multijet final states at = 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas

Journal

Journal of High Energy Physics

Published Date

2021/1

A measurement of event-shape variables in proton-proton collisions at large momentum transfer is presented using data collected at= 13 TeV with the ATLAS detector at the Large Hadron Collider. Six event-shape variables calculated using hadronic jets are studied in inclusive multijet events using data corresponding to an integrated luminosity of 139 fb− 1. Measurements are performed in bins of jet multiplicity and in different ranges of the scalar sum of the transverse momenta of the two leading jets, reaching scales beyond 2 TeV. These measurements are compared with predictions from Monte Carlo event generators containing leading-order or next-to-leading order matrix elements matched to parton showers simulated to leading-logarithm accuracy. At low jet multiplicities, shape discrepancies between the measurements and the Monte Carlo predictions are observed. At high jet multiplicities, the shapes are …

Measurement of the associated production of a Higgs boson decaying into b-quarks with a vector boson at high transverse momentum in pp collisions at s= 13 TeV with the ATLAS …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas

Journal

Physics Letters B

Published Date

2021/5/10

The associated production of a Higgs boson with a W or Z boson decaying into leptons and where the Higgs boson decays to a b b¯ pair is measured in the high vector-boson transverse momentum regime, above 250 GeV, with the ATLAS detector. The analysed data, corresponding to an integrated luminosity of 139 fb− 1, were collected in proton–proton collisions at the Large Hadron Collider between 2015 and 2018 at a centre-of-mass energy of s= 13 TeV. The measured signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model, is 0.72− 0.36+ 0.39 corresponding to an observed (expected) significance of 2.1 (2.7) standard deviations. Cross-sections of associated production of a Higgs boson decaying into b quark pairs with a W or Z gauge boson, decaying into leptons, are measured in two exclusive vector boson transverse momentum regions, 250–400 GeV and …

Study of the normalized transverse momentum distribution of bosons produced in collisions at

Authors

Victor Mukhamedovich Abazov,B Abbott,Bannanje Sripath Acharya,M Adams,Todd Adams,James P Agnew,Guennadi D Alexeev,G Alkhazov,A Alton,A Askew,Scott Atkins,Kamil Augsten,Volodymyr Aushev,Yegor Aushev,C Avila,Frederique Badaud,L Bagby,Boris Baldin,Dmitry V Bandurin,Sunanda Banerjee,Emanuela Barberis,P Baringer,JF Bartlett,U Bassler,Victor Bazterra,A Bean,Marcia Begalli,Leo Bellantoni,Suman B Beri,Gregorio Bernardi,R Bernhard,I Bertram,Marc Besancon,Raymond Beuselinck,Pushpalatha C Bhat,Sudeep Bhatia,Vipin Bhatnagar,G Blazey,S Blessing,K Bloom,A Boehnlein,D Boline,EE Boos,G Borissov,M Borysova,A Brandt,O Brandt,M Brochmann,R Brock,A Bross,D Brown,XB Bu,M Buehler,V Buescher,V Bunichev,S Burdin,CP Buszello,E Camacho-Perez,BCK Casey,H Castilla-Valdez,S Caughron,S Chakrabarti,KM Chan,A Chandra,E Chapon,G Chen,SW Cho,S Choi,B Choudhary,S Cihangir,D Claes,J Clutter,M Cooke,WE Cooper,M Corcoran,F Couderc,M-C Cousinou,J Cuth,D Cutts,A Das,G Davies,SJ de Jong,E De la Cruz-Burelo,F Deliot,R Demina,D Denisov,SP Denisov,S Desai,C Deterre,K DeVaughan,HT Diehl,M Diesburg,PF Ding,A Dominguez,A Drutskoy,A Dubey,LV Dudko,A Duperrin,S Dutt,M Eads,D Edmunds,J Ellison,VD Elvira,Y Enari,H Evans,A Evdokimov,VN Evdokimov,A Faure,L Feng,T Ferbel,F Fiedler,F Filthaut,W Fisher,HE Fisk,M Fortner,H Fox,J Franc,S Fuess,Y Fu,PH Garbincius,A Garcia-Bellido,JA Garcia-Gonzalez,V Gavrilov,W Geng,CE Gerber,Y Gershtein,G Ginther,O Gogota,G Golovanov,PD Grannis,S Greder,H Greenlee,G Grenier,Ph Gris,J-F Grivaz,A Grohsjean,S Gruenendahl,MW Gruenewald,T Guillemin,G Gutierrez,P Gutierrez,J Haley,L Han,K Harder,A Harel,JM Hauptman,J Hays,T Head,T Hebbeker,D Hedin

Journal

Physical Review D

Published Date

2021/1/5

We present a study of the normalized transverse momentum distribution of W bosons produced in p p collisions, using data corresponding to an integrated luminosity of 4.35 fb− 1 collected with the D0 detector at the Fermilab Tevatron collider at s= 1.96 TeV. The measurement focuses on the transverse momentum region below 15 GeV, which is of special interest for electroweak precision measurements; it relies on the same detector calibration methods which were used for the precision measurement of the W boson mass. The measured distribution is compared to different QCD predictions and a procedure is given to allow the comparison of any further theoretical models to the D0 data.

Search for dark matter in association with an energetic photon in pp collisions at = 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,NL Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

Journal of high energy physics

Published Date

2021/2

A search for dark matter is conducted in final states containing a photon and missing transverse momentum in proton-proton collisions at= 13 TeV. The data, collected during 2015–2018 by the ATLAS experiment at the CERN LHC, correspond to an integrated luminosity of 139 fb− 1. No deviations from the predictions of the Standard Model are observed and 95% confidence-level upper limits between 2.45 fb and 0.5 fb are set on the visible cross section for contributions from physics beyond the Standard Model, in different ranges of the missing transverse momentum. The results are interpreted as 95% confidence-level limits in models where weakly interacting dark-matter candidates are pair-produced via an s-channel axial-vector or vector mediator. Dark-matter candidates with masses up to 415 (580) GeV are excluded for axial-vector (vector) mediators, while the maximum excluded mass of the mediator is …

Search for heavy resonances decaying into a pair of Z bosons in the and final states using 139 of proton–proton collisions at TeV with …

Authors

Georges Aad,B Abbott,DC Abbott,A Abed Abud,K Abeling,DK Abhayasinghe,SH Abidi,OS AbouZeid,NL Abraham,H Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,BW Allen,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Santos,S Amoroso,CS Amrouche,F An,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,J Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Tame,G Artoni,H Asada,K Asai,S Asai,T Asawatavonvanich,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli

Journal

The European Physical Journal C

Published Date

2021/4

A search for heavy resonances decaying into a pair of Z bosons leading to and final states, where stands for either an electron or a muon, is presented. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV collected from 2015 to 2018 that corresponds to the integrated luminosity of 139 recorded by the ATLAS detector during Run 2 of the Large Hadron Collider. Different mass ranges spanning 200 GeV to 2000 GeV for the hypothetical resonances are considered, depending on the final state and model. In the absence of a significant observed excess, the results are interpreted as upper limits on the production cross section of a spin-0 or spin-2 resonance. The upper limits for the spin-0 resonance are translated to exclusion contours in the context of Type-I and Type-II two-Higgs-doublet models, and the limits for the spin-2 resonance are used to constrain the …

Search for Higgs boson production in association with a high-energy photon via vector-boson fusion with decay into bottom quark pairs at = 13 TeV with the …

Authors

Georges Aad,Brad Abbott,Dale C Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,T Asawatavonvanich,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli,WK Balunas,J Balz

Journal

Journal of high energy physics

Published Date

2021/3

A search is presented for the production of the Standard Model Higgs boson in association with a high-energy photon. With a focus on the vector-boson fusion process and the dominant Higgs boson decay into b-quark pairs, the search benefits from a large reduction of multijet background compared to more inclusive searches. Results are reported from the analysis of 132 fb− 1 of pp collision data at= 13 TeV collected with the ATLAS detector at the LHC. The measured Higgs boson signal yield in this final-state signature is 1. 3±1. 0 times the Standard Model prediction. The observed significance of the Higgs boson signal above the background is 1. 3 standard deviations, compared to an expected significance of 1. 0 standard deviations.

Search for trilepton resonances from chargino and neutralino pair production in collisions with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale C Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS Abouzeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,K Asai,S Asai,T Asawatavonvanich,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,H Bachacou,K Bachas,M Backes,F Backman,P Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,EM Baldin,P Balek,F Balli,WK Balunas,J Balz,E Banas,M Bandieramonte

Journal

Physical Review D

Published Date

2021/6/7

A search is performed for the electroweak pair production of charginos and associated production of a chargino and neutralino, each of which decays through an R-parity-violating coupling into a lepton and a W, Z, or Higgs boson. The trilepton invariant-mass spectrum is constructed from events with three or more leptons, targeting chargino decays that include an electron or muon and a leptonically decaying Z boson. The analyzed dataset corresponds to an integrated luminosity of 139 fb− 1 of proton-proton collision data produced by the Large Hadron Collider at a center-of-mass energy of s= 13 TeV and collected by the ATLAS experiment between 2015 and 2018. The data are found to be consistent with predictions from the Standard Model. The results are interpreted as limits at 95% confidence level on model-independent cross sections for processes beyond the Standard Model. Limits are also set on the …

F02 Modelling huntington’s disease progression: interpretation, staging and prognosis

Authors

Peter Wijeratne,Rachael Scahill,Sarah Tabrizi,Daniel Alexander

Published Date

2021/9/1

Background Measurements of Huntington’s disease (HD) progression, such as clinical test scores and medical imaging, can provide powerful markers for clinical applications. However, individual data can be confounded by inter-subject variability, measurement noise and hidden variables, such as disease stage. Disease progression modelling uses probabilistic methods to untangle confounding effects and hence learn patterns of disease-related changes directly from data.Aims Here we present recent developments in disease progression modelling, which we apply to i) uncover insights into HD, and ii) provide new staging and prognosis utility for clinical applications in HD.Methods We perform analyses on both cross-sectional and longitudinal data. In the cross-sectional analysis, we use the Event-Based Model (EBM) to reveal the sequence of regional brain volume and clinical marker changes from post …

pySuStaIn: a Python implementation of the Subtype and Stage Inference algorithm

Authors

Leon M Aksman,Peter A Wijeratne,Neil P Oxtoby,Arman Eshaghi,Cameron Shand,Andre Altmann,Daniel C Alexander,Alexandra L Young

Journal

SoftwareX

Published Date

2021/12/1

Progressive disorders are highly heterogeneous. Symptom-based clinical classification of these disorders may not reflect the underlying pathobiology. Data-driven subtyping and staging of patients has the potential to disentangle the complex spatiotemporal patterns of disease progression. Tools that enable this are in high demand from clinical and treatment-development communities. Here we describe the pySuStaIn software package, a Python-based implementation of the Subtype and Stage Inference (SuStaIn) algorithm. SuStaIn unravels the complexity of heterogeneous diseases by inferring multiple disease progression patterns (subtypes) and individual severity (stages) from cross-sectional data. The primary aims of pySuStaIn are to enable widespread application and translation of SuStaIn via an accessible Python package that supports simple extension and generalization to novel modeling situations …

Measurement of the relative production cross section with the ATLAS detector at

Authors

Morad Aaboud,Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,DK Abhayasinghe,SH Abidi,OS AbouZeid,NL Abraham,H Abramowicz,H Abreu,Y Abulaiti,BS Acharya,S Adachi,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,M Adersberger,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,F Ahmadov,G Aielli,S Akatsuka,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,D Alexandre,T Alexopoulos,A Alfonsi,M Alhroob,B Ali,G Alimonti,J Alison,SP Alkire,C Allaire,BMM Allbrooke,BW Allen,PP Allport,A Aloisio,A Alonso,F Alonso,C Alpigiani,AA Alshehri,MI Alstaty,M Alvarez Estevez,B Alvarez Gonzalez,D Álvarez Piqueras,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,F An,C Anastopoulos,N Andari,T Andeen,CF Anders,JK Anders,A Andreazza,V Andrei,CR Anelli,S Angelidakis,I Angelozzi,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,L Aperio Bella,G Arabidze,JP Araque,V Araujo Ferraz,R Araujo Pereira,ATH Arce,FA Arduh,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,LJ Armitage,A Armstrong,O Arnaez,H Arnold,A Artamonov,G Artoni,S Artz,S Asai,NA Asbah,EM Asimakopoulou,L Asquith,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,K Augsten,G Avolio,R Avramidou,MK Ayoub,AM Azoulay,G Azuelos,AE Baas,MJ Baca,H Bachacou,K Bachas,M Backes,F Backman,P Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,M Bajic,C Bakalis,OK Baker,PJ Bakker,D Bakshi Gupta,S Balaji,EM Baldin,P Balek,F Balli,WK Balunas

Journal

Physical Review D

Published Date

2021/7/26

The total cross section and differential cross sections for the production of B c±mesons, times their branching fraction to J/ψ π±, are measured relative to those for the production of B±mesons, times their branching fraction to J/ψ K±. The data used for this study correspond to an integrated luminosity of 20.3 fb− 1 of p p collisions recorded by the ATLAS detector at the Large Hadron Collider in 2012 at a center-of-mass energy of s= 8 TeV. The measurement is performed differentially in bins of transverse momentum p T for 13 GeV< p T (B c±)< 22 GeV and p T (B c±)> 22 GeV and in bins of rapidity y for| y|< 0.75 and 0.75<| y|< 2.3. The relative cross section times branching fraction for the full range p T> 13 GeV and| y|< 2.3 is (0.34±0.0 4 stat− 0.02+ 0.06 sys±0.0 1 lifetime)%. The differential measurements suggest that the production cross section of the B c±decreases faster with p T than the production cross section of the …

From tumour perfusion to drug delivery and clinical translation of in silico cancer models

Authors

Myrianthi Hadjicharalambous,Peter A Wijeratne,Vasileios Vavourakis

Published Date

2021/1/1

In silico cancer models have demonstrated great potential as a tool to improve drug design, optimise the delivery of drugs to target sites in the host tissue and, hence, improve therapeutic efficacy and patient outcome. However, there are significant barriers to the successful translation of in silico technology from bench to bedside. More precisely, the specification of unknown model parameters, the necessity for models to adequately reflect in vivo conditions, and the limited amount of pertinent validation data to evaluate models’ accuracy and assess their reliability, pose major obstacles in the path towards their clinical translation. This review aims to capture the state-of-the-art in in silico cancer modelling of vascularised solid tumour growth, and identify the important advances and barriers to success of these models in clinical oncology. Particular emphasis has been put on continuum-based models of cancer since …

Search for phenomena beyond the Standard Model in events with large b-jet multiplicity using the ATLAS detector at the LHC

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,NL Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,J Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,J-F Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

The European Physical Journal C

Published Date

2021/1

A search is presented for new phenomena in events characterised by high jet multiplicity, no leptons (electrons or muons), and four or more jets originating from the fragmentation of b-quarks (b-jets). The search uses of= 13 TeV proton–proton collision data collected by the ATLAS experiment at the Large Hadron Collider during Run 2. The dominant Standard Model background originates from multijet production and is estimated using a data-driven technique based on an extrapolation from events with low b-jet multiplicity to the high b-jet multiplicities used in the search. No significant excess over the Standard Model expectation is observed and 95% confidence-level limits that constrain simplified models of R-parity-violating supersymmetry are determined. The exclusion limits reach 950 GeV in top-squark mass in the models considered.

Observation of photon-induced W+ W− production in pp collisions at s= 13 TeV using the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,N Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

Physics Letters B

Published Date

2021/5/10

This letter reports the observation of photon-induced production of W-boson pairs, γ γ→ W W. The analysis uses 139 fb− 1 of LHC proton–proton collision data taken at s= 13 TeV recorded by the ATLAS experiment during the years 2015–2018. The measurement is performed selecting one electron and one muon, corresponding to the decay of the diboson system as W W→ e±ν μ∓ ν final state. The background-only hypothesis is rejected with a significance of well above 5 standard deviations consistent with the expectation from Monte Carlo simulation. A cross section for the γ γ→ W W process of 3.13±0.31 (stat.)±0.28 (syst.) fb is measured in a fiducial volume close to the acceptance of the detector, by requiring an electron and a muon of opposite signs with large dilepton transverse momentum and exactly zero additional charged particles. This is found to be in agreement with the Standard Model prediction.

Search for new phenomena in final states with -jets and missing transverse momentum in TeV collisions with the ATLAS detector

Authors

Atlas Collaboration

Journal

arXiv preprint arXiv:2101.12527

Published Date

2021/1/29

The results of a search for new phenomena in final states with -jets and missing transverse momentum using 139 fb of proton-proton data collected at a centre-of-mass energy TeV by the ATLAS detector at the LHC are reported. The analysis targets final states produced by the decay of a pair-produced supersymmetric bottom squark into a bottom quark and a stable neutralino. The analysis also seeks evidence for models of pair production of dark matter particles produced through the decay of a generic scalar or pseudoscalar mediator state in association with a pair of bottom quarks, and models of pair production of scalar third-generation down-type leptoquarks. No significant excess of events over the Standard Model background expectation is observed in any of the signal regions considered by the analysis. Bottom squark masses below 1270 GeV are excluded at 95% confidence level if the neutralino is massless. In the case of nearly mass-degenerate bottom squarks and neutralinos, the use of dedicated secondary-vertex identification techniques permits the exclusion of bottom squarks with masses up to 660 GeV for mass splittings between the squark and the neutralino of 10 GeV. These limits extend substantially beyond the regions of parameter space excluded by similar ATLAS searches performed previously.

Measurement of the CP-violating phase in decays in ATLAS at 13 TeV

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Ovsat Abdinov,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,NL Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Shunsuke Adachi,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Didier Alexandre,Theodoros Alexopoulos,Alice Alfonsi,Muhammad Alhroob,Babar Ali,Gianluca Alimonti,John Alison,Steven Patrick Alkire,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Alejandro Alonso,Francisco Alonso,Cristiano Alpigiani,Azzah Aziz Alshehri,M Alvarez Estevez,D Álvarez Piqueras,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,Christoph Falk Anders,John Kenneth Anders,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,L Aperio Bella,Giorgi Arabidze,JP Araque,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Lewis James Armitage,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,Andrei Artamonov,Giacomo Artoni,Sebastian Artz,Shoji Asai,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Giuseppe Avolio,R Avramidou,Mohamad Kassem Ayoub,Adam Maxwell Azoulay,Georges Azuelos,Matthew John Baca,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Milena Bajic,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek

Journal

The European Physical Journal C

Published Date

2021/4

A measurement of the decay parameters using of integrated luminosity collected with the ATLAS detector from 13  proton–proton collisions at the LHC is presented. The measured parameters include the CP-violating phase , the width difference between the meson mass eigenstates and the average decay width . The values measured for the physical parameters are combined with those from of 7 and 8  data, leading to the following: $$\begin{aligned} \phi _{s}= & {} -0.087 \pm 0.036 ~\mathrm {(stat.)} \pm 0.021 ~\mathrm {(syst.)~rad} \\ \Delta \Gamma _{s}= & {} 0.0657 \pm 0.0043 ~\mathrm {(stat.)}\pm 0.0037 ~\mathrm {(syst.)~ps}^{-1} \\ \Gamma _{s}= & {} 0.6703 \pm 0.0014 ~\mathrm {(stat.)}\pm 0.0018 ~\mathrm {(syst.)~ps}^{-1} \end{aligned}$$Results for and are also presented as 68% confidence level contours in the – plane. Furthermore the transversity …

Search for doubly and singly charged Higgs bosons decaying into vector bosons in multi-lepton final states with the ATLAS detector using proton-proton collisions at $$\sqrt …

Authors

Georges Aad,Brad Abbott,Dale C Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,C Arcangeletti,ATH Arce,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,T Asawatavonvanich,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli,WK Balunas,J Balz,E Banas

Journal

Journal of High Energy Physics

Published Date

2021/6

A search for charged Higgs bosons decaying into W±W±or W±Z bosons is performed, involving experimental signatures with two leptons of the same charge, or three or four leptons with a variety of charge combinations, missing transverse momentum and jets. A data sample of proton-proton collisions at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider between 2015 and 2018 is used. The data correspond to a total integrated luminosity of 139 fb− 1. The search is guided by a type-II seesaw model that extends the scalar sector of the Standard Model with a scalar triplet, leading to a phenomenology that includes doubly and singly charged Higgs bosons. Two scenarios are explored, corresponding to the pair production of doubly charged H±±bosons, or the associated production of a doubly charged H±±boson and a singly charged H±boson. No significant deviations …

E03 Uncovering the temporal sequence of regional brain volume and neural connectivity changes in huntington’s disease

Authors

Alexandra Moura,Juliette Champaud,Rachael Scahill,Sarah Tabrizi,Daniel Alexander,Peter Wijeratne

Published Date

2021/9/1

Background Huntington Disease (HD) is a neurodegenerative disorder that can be characterised by magnetic resonance imaging (MRI) measurements of brain volume loss and neural connectivity changes. We recently developed a probabilistic disease progression model to uncover the most likely temporal sequence of structural MRI changes occurring during HD progression. However, there is currently less information regarding the ordering of neural connectivity changes and whether these precede or follow brain volume loss.Aims Here we aim to expand our previous model by including neural connectivity markers to uncover a new temporal sequence of events occurring in the HD brain. This model is the first of its kind, providing insight into HD disease mechanisms and progression, and potentially guiding future treatments by determining the most optimal stage for intervention.Method We apply the event-based …

Search for type-III seesaw heavy leptons in dilepton final states in pp collisions at with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale C Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek

Journal

The European Physical Journal C

Published Date

2021/3

A search for the pair production of heavy leptons as predicted by the type-III seesaw mechanism is presented. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV, corresponding to of integrated luminosity recorded by the ATLAS detector during Run 2 of the Large Hadron Collider. The analysis focuses on the final state with two light leptons (electrons or muons) of different flavour and charge combinations, with at least two jets and large missing transverse momentum. No significant excess over the Standard Model expectation is observed. The results are translated into exclusion limits on heavy-lepton masses, and the observed lower limit on the mass of the type-III seesaw heavy leptons is 790 GeV at 95% confidence level.

Evaluation of automated airway morphological quantification for assessing fibrosing lung disease

Authors

Ashkan Pakzad,Wing Keung Cheung,Kin Quan,Nesrin Mogulkoc,Coline HM Van Moorsel,Brian J Bartholmai,Hendrik W Van Es,Alper Ezircan,Frouke Van Beek,Marcel Veltkamp,Ronald Karwoski,Tobias Peikert,Ryan D Clay,Finbar Foley,Cassandra Braun,Recep Savas,Carole Sudre,Tom Doel,Daniel C Alexander,Peter Wijeratne,David Hawkes,Yipeng Hu,John R Hurst,Joseph Jacob

Journal

arXiv preprint arXiv:2111.10443

Published Date

2021/11/19

Abnormal airway dilatation, termed traction bronchiectasis, is a typical feature of idiopathic pulmonary fibrosis (IPF). Volumetric computed tomography (CT) imaging captures the loss of normal airway tapering in IPF. We postulated that automated quantification of airway abnormalities could provide estimates of IPF disease extent and severity. We propose AirQuant, an automated computational pipeline that systematically parcellates the airway tree into its lobes and generational branches from a deep learning based airway segmentation, deriving airway structural measures from chest CT. Importantly, AirQuant prevents the occurrence of spurious airway branches by thick wave propagation and removes loops in the airway-tree by graph search, overcoming limitations of existing airway skeletonisation algorithms. Tapering between airway segments (intertapering) and airway tortuosity computed by AirQuant were compared between 14 healthy participants and 14 IPF patients. Airway intertapering was significantly reduced in IPF patients, and airway tortuosity was significantly increased when compared to healthy controls. Differences were most marked in the lower lobes, conforming to the typical distribution of IPF-related damage. AirQuant is an open-source pipeline that avoids limitations of existing airway quantification algorithms and has clinical interpretability. Automated airway measurements may have potential as novel imaging biomarkers of IPF severity and disease extent.

Two-particle azimuthal correlations in photonuclear ultraperipheral collisions at 5.02 TeV with ATLAS

Authors

Georges Aad,Brad Abbott,Dale C Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,H Abreu,Y Abulaiti,AC Abusleme Hoffman,BS Acharya,B Achkar,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,C Arcangeletti,ATH Arce,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,F Backman,P Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli,WK Balunas,J Balz,E Banas,M Bandieramonte

Journal

Physical Review C

Published Date

2021/7/12

Two-particle long-range azimuthal correlations are measured in photonuclear collisions using 1.7 nb− 1 of 5.02 TeV Pb+ Pb collision data collected by the ATLAS experiment at the CERN Large Hadron Collider. Candidate events are selected using a dedicated high-multiplicity photonuclear event trigger, a combination of information from the zero-degree calorimeters and forward calorimeters, and from pseudorapidity gaps constructed using calorimeter energy clusters and charged-particle tracks. Distributions of event properties are compared between data and Monte Carlo simulations of photonuclear processes. Two-particle correlation functions are formed using charged-particle tracks in the selected events, and a template-fitting method is employed to subtract the nonflow contribution to the correlation. Significant nonzero values of the second-and third-order flow coefficients are observed and presented as a …

Exclusive dimuon production in ultraperipheral collisions at with ATLAS

Authors

Georges Aad,Brad Abbott,Dale C Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,J-F Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,NA Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,K Bachas,Filip Backman,Paolo Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,R Balasubramanian,EM Baldin,P Balek,F Balli

Journal

Physical Review C

Published Date

2021/8/19

Exclusive dimuon production in ultraperipheral collisions (UPC), resulting from photon-photon interactions in the strong electromagnetic fields of colliding high-energy lead nuclei, PbPb (γ γ)→ μ+ μ−(Pb (★) Pb (★)), is studied using L int= 0.48 nb− 1 of s N N= 5.02 TeV lead-lead collision data at the LHC with the ATLAS detector. Dimuon pairs are measured in the fiducial region p T, μ> 4 GeV,| η μ|< 2.4, invariant mass m μ μ> 10 GeV, and p T, μ μ< 2 GeV. The primary background from single-dissociative processes is extracted from the data using a template fitting technique. Differential cross sections are presented as a function of m μ μ, absolute pair rapidity (| y μ μ|), scattering angle in the dimuon rest frame (| cos ϑ μ μ★|), and the colliding photon energies. The total cross section of the UPC γ γ→ μ+ μ− process in the fiducial volume is measured to be σ fid μ μ= 34.1±0.3 (stat.)±0.7 (syst.) μ b. Generally good …

Measurements of WH and ZH production in the H→ bb¯ decay channel in pp collisions at 13Te with the ATLAS detector

Authors

ATLAS Collaboration

Published Date

2021

Measurements of the Standard Model Higgs boson decaying into a bb¯ pair and produced in association with a W or Z boson decaying into leptons, using proton–proton collision data collected between 2015 and 2018 by the ATLAS detector, are presented. The measurements use collisions produced by the Large Hadron Collider at a centre-of-mass energy of s=13Te, corresponding to an integrated luminosity of 139fb-1. The production of a Higgs boson in association with a W or Z boson is established with observed (expected) significances of 4.0 (4.1) and 5.3 (5.1) standard deviations, respectively. Cross-sections of associated production of a Higgs boson decaying into bottom quark pairs with an electroweak gauge boson, W or Z, decaying into leptons are measured as a function of the gauge boson transverse momentum in kinematic fiducial volumes. The cross-section measurements are all consistent with the Standard Model expectations, and the total uncertainties vary from 30% in the high gauge boson transverse momentum regions to 85% in the low regions. Limits are subsequently set on the parameters of an effective Lagrangian sensitive to modifications of the WH and ZH processes as well as the Higgs boson decay into bb¯.

Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data

Authors

Arman Eshaghi,Alexandra L Young,Peter A Wijeratne,Ferran Prados,Douglas L Arnold,Sridar Narayanan,Charles RG Guttmann,Frederik Barkhof,Daniel C Alexander,Alan J Thompson,Declan Chard,Olga Ciccarelli

Journal

Nature communications

Published Date

2021/4/6

Multiple sclerosis (MS) can be divided into four phenotypes based on clinical evolution. The pathophysiological boundaries of these phenotypes are unclear, limiting treatment stratification. Machine learning can identify groups with similar features using multidimensional data. Here, to classify MS subtypes based on pathological features, we apply unsupervised machine learning to brain MRI scans acquired in previously published studies. We use a training dataset from 6322 MS patients to define MRI-based subtypes and an independent cohort of 3068 patients for validation. Based on the earliest abnormalities, we define MS subtypes as cortex-led, normal-appearing white matter-led, and lesion-led. People with the lesion-led subtype have the highest risk of confirmed disability progression (CDP) and the highest relapse rate. People with the lesion-led MS subtype show positive treatment response in selected …

The ATLAS fast TracKer system

Authors

Atlas Collaboration

Journal

arXiv preprint arXiv:2101.05078

Published Date

2021/1/12

The ATLAS Fast TracKer (FTK) was designed to provide full tracking for the ATLAS high-level trigger by using pattern recognition based on Associative Memory (AM) chips and fitting in high-speed field programmable gate arrays. The tracks found by the FTK are based on inputs from all modules of the pixel and silicon microstrip trackers. The as-built FTK system and components are described, as is the online software used to control them while running in the ATLAS data acquisition system. Also described is the simulation of the FTK hardware and the optimization of the AM pattern banks. An optimization for long-lived particles with large impact parameter values is included. A test of the FTK system with the data playback facility that allowed the FTK to be commissioned during the shutdown between Run 2 and Run 3 of the LHC is reported. The resulting tracks from part of the FTK system covering a limited - region of the detector are compared with the output from the FTK simulation. It is shown that FTK performance is in good agreement with the simulation.

Search for pair production of third-generation scalar leptoquarks decaying into a top quark and a τ-lepton in pp collisions at = 13 TeV with the ATLAS detector

Authors

Georges Aad,Braden Abbott,Dale C Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,Ossama S AbouZeid,Nicola Louise Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,S Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,Sara Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,Philip Patrick Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,Dante Amidei,SP Amor Dos Santos,Simone Amoroso,Fenfen An,Christos Anastopoulos,T Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,Victor Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Jean-Francois Arguin,Spyros Argyropoulos,J-H Arling,Aaron James Armbruster,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Alexandra Asbah,Lily Asquith,Jihad Assahsah,K Assamagan,Robert Astalos,Ryan Justin Atkin,M Atkinson,Naim Bora Atlay,Hicham Atmani,PA Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,K Bachas,F Backman,Paolo Bagnaia,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz,Elzbieta Banas,Marilena Bandieramonte,Anjishnu Bandyopadhyay,Sw Banerjee

Journal

Journal of high energy physics

Published Date

2021/6

A search for pair production of third-generation scalar leptoquarks decaying into a top quark and a τ-lepton is presented. The search is based on a dataset of pp collisions at= 13 TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb− 1. Events are selected if they have one light lepton (electron or muon) and at least one hadronically decaying τ-lepton, or at least two light leptons. In addition, two or more jets, at least one of which must be identified as containing b-hadrons, are required. Six final states, defined by the multiplicity and flavour of lepton candidates, are considered in the analysis. Each of them is split into multiple event categories to simultaneously search for the signal and constrain several leading backgrounds. The signal-rich event categories require at least one hadronically decaying τ-lepton candidate and exploit the …

Optimisation of large-radius jet reconstruction for the ATLAS detector in 13 TeV proton–proton collisions

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,J Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin

Journal

The European Physical Journal C

Published Date

2021/4

Jet substructure has provided new opportunities for searches and measurements at the LHC, and has seen continuous development since the optimization of the large-radius jet definition used by ATLAS was performed during Run 1. A range of new inputs to jet reconstruction, pile-up mitigation techniques and jet grooming algorithms motivate an optimisation of large-radius jet reconstruction for ATLAS. In this paper, this optimisation procedure is presented, and the performance of a wide range of large-radius jet definitions is compared. The relative performance of these jet definitions is assessed using metrics such as their pileup stability, ability to identify hadronically decaying W bosons and top quarks with large transverse momenta. A new type of jet input object, called a ‘unified flow object’is introduced which combines calorimeter-and inner-detector-based signals in order to achieve optimal performance across a …

Sequence of clinical and neurodegeneration events in Parkinson’s disease progression

Authors

Neil P Oxtoby,Louise-Ann Leyland,Leon M Aksman,George EC Thomas,Emma L Bunting,Peter A Wijeratne,Alexandra L Young,Angelika Zarkali,Manuela MX Tan,Fion D Bremner,Pearse A Keane,Huw R Morris,Anette E Schrag,Daniel C Alexander,Rimona S Weil

Journal

Brain

Published Date

2021/3/1

Dementia is one of the most debilitating aspects of Parkinson’s disease. There are no validated biomarkers that can track Parkinson’s disease progression, nor accurately identify patients who will develop dementia and when. Understanding the sequence of observable changes in Parkinson’s disease in people at elevated risk for developing dementia could provide an integrated biomarker for identifying and managing individuals who will develop Parkinson’s dementia. We aimed to estimate the sequence of clinical and neurodegeneration events, and variability in this sequence, using data-driven statistical modelling in two separate Parkinson’s cohorts, focusing on patients at elevated risk for dementia due to their age at symptom onset. We updated a novel version of an event-based model that has only recently been extended to cope naturally with clinical data, enabling its application in Parkinson’s disease …

Search for resonances decaying into a weak vector boson and a Higgs boson in the fully hadronic final state produced in collisions at with …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek

Journal

Physical Review D

Published Date

2020/12/17

A search for heavy resonances decaying into a W or Z boson and a Higgs boson produced in proton− proton collisions at the Large Hadron Collider at s= 13 TeV is presented. The analysis utilizes the dominant W→ q q′ or Z→ q q and H→ b b decays with substructure techniques applied to large-radius jets. A sample corresponding to an integrated luminosity of 139 fb− 1 collected with the ATLAS detector is analyzed and no significant excess of data is observed over the background prediction. The results are interpreted in the context of the heavy vector triplet model with spin-1 W′ and Z′ bosons. Upper limits on the cross section are set for resonances with mass between 1.5 and 5.0 TeV, ranging from 6.8 to 0.53 fb for W′→ W H and from 8.7 to 0.53 fb for Z′→ Z H at the 95% confidence level.

Observation and measurement of forward proton scattering in association with lepton pairs produced via the photon fusion mechanism at ATLAS

Authors

Atlas Collaboration

Journal

arXiv preprint arXiv:2009.14537

Published Date

2020/9/30

The observation of forward proton scattering in association with lepton pairs ( or ) produced via photon fusion is presented. The scattered proton is detected by the ATLAS Forward Proton spectrometer while the leptons are reconstructed by the central ATLAS detector. Proton-proton collision data recorded in 2017 at a center-of-mass energy of TeV are analyzed, corresponding to an integrated luminosity of 14.6 fb. A total of 57 (123) candidates in the () final state are selected, allowing the background-only hypothesis to be rejected with a significance exceeding five standard deviations in each channel. Proton-tagging techniques are introduced for cross-section measurements in the fiducial detector acceptance, corresponding to = 11.0 2.6 (stat.) 1.2 (syst.) 0.3 (lumi.) fb and = 7.2 1.6 (stat.) 0.9 (syst.) 0.2 (lumi.) fb in the dielectron and dimuon channel, respectively.

Measurements of the Higgs boson inclusive and differential fiducial cross sections in the 4 ℓ decay channel at s = 13 TeV

Authors

Georges Aad,Brad Abbott,Dale C Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,Asmaa Aboulhorma,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,AC Abusleme Hoffman,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,SV Addepalli,Jahred Adelman,Aytül Adiguzel,S Adorni,Tim Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,J Agarwala,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,I Aizenberg,S Akatsuka,M Akbiyik,TPA Åkesson,AV Akimov,K Al Khoury,GL Alberghi,J Albert,P Albicocco,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,KR Amos,CS Amrouche,V Ananiev,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal,V Araujo Ferraz,C Arcangeletti,ATH Arce,E Arena,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,H Asada,K Asai,S Asai,NA Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,PA Atmasiddha,K Augsten,S Auricchio,VA Austrup,G Avner,G Avolio,MK Ayoub,G Azuelos,D Babal,H Bachacou,K Bachas,A Bachiu,F Backman,A Badea,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji

Journal

Journal of High Energy Physics

Published Date

2022/8

A measurement of inclusive and differential fiducial cross-sections for the production of the Higgs boson decaying into two photons is performed using 139 fb− 1 of proton-proton collision data recorded at= 13 TeV by the ATLAS experiment at the Large Hadron Collider. The inclusive cross-section times branching ratio, in a fiducial region closely matching the experimental selection, is measured to be 67±6 fb, which is in agreement with the state-of-the-art Standard Model prediction of 64±4 fb. Extrapolating this result to the full phase space and correcting for the branching ratio, the total cross-section for Higgs boson production is estimated to be 58±6 pb. In addition, the cross-sections in four fiducial regions sensitive to various Higgs boson production modes and differential cross-sections as a function of either one or two of several observables are measured. All the measurements are found to be in agreement …

Performance of the upgraded PreProcessor of the ATLAS Level-1 Calorimeter Trigger

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,Azzah Aziz Alshehri,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,Christoph Falk Anders,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Pozo,MA Aparo,L Aperio Bella,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Tame,Giacomo Artoni,Sebastian Artz,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz,Elzbieta Banas

Journal

Journal of instrumentation

Published Date

2020/11/10

The Large Hadron Collider (LHC) at CERN accelerates protons to an energy of 6.5 TeV and brings them into collision at four interaction points, with a frequency of 40 MHz. Installed at one of these points is the ATLAS detector [1–3], which records the properties of particles produced in the collisions for later physics analysis. The ATLAS experiment investigates a wide range of physics topics, with the primary focus of improving our understanding of the fundamental constituents of matter, and the interactions among them. One of the most important goals for the first data-taking period of the LHC from 2009 to 2013 (Run 1) was to find and start measuring the properties of the long-sought Higgs boson, which was successfully discovered by the ATLAS and CMS collaborations in 2012 [4, 5].Due to the high rate of collisions, only a small subset of the produced events can be recorded for later analysis. A powerful trigger …

Tau‐first subtype of Alzheimer’s disease progression consistently identified through PET and CSF: Neuroimaging: Understanding tau progression

Authors

Leon M Aksman,Neil P Oxtoby,Marzia Antonella Scelsi,Peter A Wijeratne,Alexandra L Young,Isadora Lopes Alves,Daniel C Alexander,Frederik Barkhof,Andre Altmann

Journal

Alzheimer's & Dementia

Published Date

2020/12

Background Several studies contend that some Alzheimer’s disease (AD) subjects develop early‐stage tau pathology before amyloid pathology1,2, supporting a hypothesis that there are multiple distinct subtypes of amyloid and tau pathology progression within AD. We investigated this hypothesis, applying data‐driven disease subtyping models to both amyloid and tau PET as well as CSF measures. Method We performed two separate analyses using cross‐sectional data from ADNI. The first was a tau‐PET‐based analysis, which used eight regional amyloid PET (AV‐45) SUVRs and ten tau PET (AV‐1451) SUVRs from 402 subjects with both scans at the same visit. The second was a tau‐CSF‐based analysis, substituting CSF‐based prediction of tau PET SUVR (see Figure 2) in place of actual tau PET to give a larger dataset of 996 subjects. We used the Subtype and Stage Inference (SuStaIn3) algorithm to …

Studies of and production in collisions at 1.96 TeV

Authors

Victor Mukhamedovich Abazov,B Abbott,Bannanje Sripath Acharya,M Adams,Todd Adams,James P Agnew,Guennadi D Alexeev,G Alkhazov,A Alton,A Askew,Scott Atkins,Kamil Augsten,Volodymyr Aushev,Yegor Aushev,C Avila,Frederique Badaud,L Bagby,Boris Baldin,Dmitry V Bandurin,Sunanda Banerjee,Emanuela Barberis,P Baringer,JF Bartlett,U Bassler,Victor Bazterra,A Bean,Marcia Begalli,Leo Bellantoni,Suman B Beri,Gregorio Bernardi,R Bernhard,I Bertram,Marc Besancon,Raymond Beuselinck,Pushpalatha C Bhat,Sudeep Bhatia,Vipin Bhatnagar,G Blazey,S Blessing,K Bloom,A Boehnlein,D Boline,EE Boos,G Borissov,M Borysova,A Brandt,O Brandt,M Brochmann,R Brock,A Bross,D Brown,XB Bu,M Buehler,V Buescher,V Bunichev,S Burdin,CP Buszello,E Camacho-Perez,BCK Casey,H Castilla-Valdez,S Caughron,S Chakrabarti,KM Chan,A Chandra,E Chapon,G Chen,SW Cho,S Choi,B Choudhary,S Cihangir,D Claes,J Clutter,M Cooke,WE Cooper,M Corcoran,F Couderc,M-C Cousinou,J Cuth,D Cutts,A Das,G Davies,SJ de Jong,E De La Cruz-Burelo,F Deliot,R Demina,D Denisov,SP Denisov,S Desai,C Deterre,K DeVaughan,HT Diehl,M Diesburg,PF Ding,A Dominguez,A Drutskoy,A Dubey,LV Dudko,A Duperrin,S Dutt,M Eads,D Edmunds,J Ellison,VD Elvira,Y Enari,H Evans,A Evdokimov,VN Evdokimov,A Faure,L Feng,T Ferbel,F Fiedler,F Filthaut,W Fisher,HE Fisk,M Fortner,H Fox,J Franc,S Fuess,PH Garbincius,A Garcia-Bellido,JA Garcia-Gonzalez,V Gavrilov,W Geng,CE Gerber,Y Gershtein,G Ginther,O Gogota,G Golovanov,PD Grannis,S Greder,H Greenlee,G Grenier,Ph Gris,J-F Grivaz,A Grohsjean,S Grünendahl,MW Grünewald,T Guillemin,G Gutierrez,P Gutierrez,J Haley,L Han,K Harder,A Harel,JM Hauptman,J Hays,T Head,T Hebbeker,D Hedin,H Hegab

Journal

Physical Review D

Published Date

2020/10/13

We present various properties of the production of the X (3872) and ψ (2 S) states based on 10.4 fb− 1 collected by the D0 experiment in Tevatron p p collisions at s= 1.96 TeV. For both states, we measure the nonprompt fraction f N P of the inclusive production rate due to decays of b-flavored hadrons. We find the f N P values systematically below those obtained at the LHC. The f N P fraction for ψ (2 S) increases with transverse momentum, whereas for the X (3872) it is constant within large uncertainties, in agreement with the LHC results. The ratio of prompt to nonprompt ψ (2 S) production,(1− f N P)/f N P, decreases only slightly going from the Tevatron to the LHC, but for the X (3872), this ratio decreases by a factor of about 3. We test the soft-pion signature of the X (3872) modeled as a weakly bound charm-meson pair by studying the production of the X (3872) as a function of the kinetic energy of the X (3872) and …

Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease

Authors

Filipe B Rodrigues,Lauren M Byrne,Rosanna Tortelli,Eileanoir B Johnson,Peter A Wijeratne,Marzena Arridge,Enrico De Vita,Naghmeh Ghazaleh,Richard Houghton,Hannah Furby,Daniel C Alexander,Sarah J Tabrizi,Scott Schobel,Rachael I Scahill,Amanda Heslegrave,Henrik Zetterberg,Edward J Wild

Journal

Science translational medicine

Published Date

2020/12/16

The longitudinal dynamics of the most promising biofluid biomarker candidates for Huntington’s disease (HD)—mutant huntingtin (mHTT) and neurofilament light (NfL)—are incompletely defined. Characterizing changes in these candidates during disease progression could increase our understanding of disease pathophysiology and help the identification of effective therapies. In an 80-participant cohort over 24 months, mHTT in cerebrospinal fluid (CSF), as well as NfL in CSF and blood, had distinct longitudinal trajectories in HD mutation carriers compared with controls. Baseline analyte values predicted clinical disease status, subsequent clinical progression, and brain atrophy, better than did the rate of change in analytes. Overall, NfL was a stronger monitoring and prognostic biomarker for HD than mHTT. Nonetheless, mHTT has prognostic value and might be a valuable pharmacodynamic marker for huntingtin …

Dijet Resonance Search with Weak Supervision Using Collisions in the ATLAS Detector

Authors

G Aad,B Abbott,DC Abbott,A Abed Abud,K Abeling,DK Abhayasinghe,SH Abidi,OS AbouZeid,NL Abraham,H Abramowicz,H Abreu,Y Abulaiti,BS Acharya,B Achkar,L Adam,C Adam Bourdarios,L Adamczyk,L Adamek,J Adelman,M Adersberger,A Adiguzel,S Adorni,T Adye,AA Affolder,Y Afik,C Agapopoulou,MN Agaras,A Aggarwal,C Agheorghiesei,JA Aguilar-Saavedra,A Ahmad,F Ahmadov,WS Ahmed,X Ai,G Aielli,S Akatsuka,M Akbiyik,TPA Åkesson,E Akilli,AV Akimov,K Al Khoury,GL Alberghi,J Albert,MJ Alconada Verzini,S Alderweireldt,M Aleksa,IN Aleksandrov,C Alexa,T Alexopoulos,A Alfonsi,F Alfonsi,M Alhroob,B Ali,S Ali,M Aliev,G Alimonti,C Allaire,BMM Allbrooke,BW Allen,PP Allport,A Aloisio,F Alonso,C Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,A Ambler,L Ambroz,C Amelung,D Amidei,SP Amor Dos Santos,S Amoroso,CS Amrouche,F An,C Anastopoulos,N Andari,T Andeen,JK Anders,SY Andrean,A Andreazza,V Andrei,CR Anelli,S Angelidakis,A Angerami,AV Anisenkov,A Annovi,C Antel,MT Anthony,E Antipov,M Antonelli,DJA Antrim,F Anulli,M Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,C Arcangeletti,ATH Arce,FA Arduh,JF Arguin,S Argyropoulos,J-H Arling,AJ Armbruster,A Armstrong,O Arnaez,H Arnold,ZP Arrubarrena Tame,G Artoni,K Asai,S Asai,T Asawatavonvanich,N Asbah,EM Asimakopoulou,L Asquith,J Assahsah,K Assamagan,R Astalos,RJ Atkin,M Atkinson,NB Atlay,H Atmani,K Augsten,VA Austrup,G Avolio,MK Ayoub,G Azuelos,H Bachacou,K Bachas,M Backes,F Backman,P Bagnaia,M Bahmani,H Bahrasemani,AJ Bailey,VR Bailey,JT Baines,C Bakalis,OK Baker,PJ Bakker,E Bakos,D Bakshi Gupta,S Balaji,EM Baldin,P Balek,F Balli,WK Balunas

Journal

Physical Review Letters

Published Date

2020/9/21

This Letter describes a search for narrowly resonant new physics using a machine-learning anomaly detection procedure that does not rely on signal simulations for developing the analysis selection. Weakly supervised learning is used to train classifiers directly on data to enhance potential signals. The targeted topology is dijet events and the features used for machine learning are the masses of the two jets. The resulting analysis is essentially a three-dimensional search A→ B C, for m A∼ O (TeV), m B, m C∼ O (100 GeV) and B, C are reconstructed as large-radius jets, without paying a penalty associated with a large trials factor in the scan of the masses of the two jets. The full run 2 s= 13 TeV p p collision dataset of 139 fb− 1 recorded by the ATLAS detector at the Large Hadron Collider is used for the search. There is no significant evidence of a localized excess in the dijet invariant mass spectrum between 1.8 …

Higgs boson production cross-section measurements and their EFT interpretation in the decay channel at 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz

Journal

The European Physical Journal C

Published Date

2020/10

Higgs boson properties are studied in the four-lepton decay channel (where lepton = e, ) using 139  of proton–proton collision data recorded at 13 TeV by the ATLAS experiment at the Large Hadron Collider. The inclusive cross-section times branching ratio for decay is measured to be  pb for a Higgs boson with absolute rapidity below 2.5, in good agreement with the Standard Model prediction of  pb. Cross-sections times branching ratio are measured for the main Higgs boson production modes in several exclusive phase-space regions. The measurements are interpreted in terms of coupling modifiers and of the tensor structure of Higgs boson interactions using an effective field theory approach. Exclusion limits are set on the CP-even and CP-odd ‘beyond the Standard Model’ couplings of the Higgs boson to vector bosons, gluons and top quarks.

Learning transition times in event sequences: the event-based hidden markov model of disease progression

Authors

Peter A Wijeratne,Daniel C Alexander

Journal

arXiv preprint arXiv:2011.01023

Published Date

2020/11/2

Progressive diseases worsen over time and are characterised by monotonic change in features that track disease progression. Here we connect ideas from two formerly separate methodologies -- event-based and hidden Markov modelling -- to derive a new generative model of disease progression. Our model can uniquely infer the most likely group-level sequence and timing of events (natural history) from limited datasets. Moreover, it can infer and predict individual-level trajectories (prognosis) even when data are missing, giving it high clinical utility. Here we derive the model and provide an inference scheme based on the expectation maximisation algorithm. We use clinical, imaging and biofluid data from the Alzheimer's Disease Neuroimaging Initiative to demonstrate the validity and utility of our model. First, we train our model to uncover a new group-level sequence of feature changes in Alzheimer's disease over a period of years. Next, we demonstrate that our model provides improved utility over a continuous time hidden Markov model by area under the receiver operator characteristic curve . Finally, we demonstrate that our model maintains predictive accuracy with up to missing data. These results support the clinical validity of our model and its broader utility in resource-limited medical applications.

Determination of jet calibration and energy resolution in proton–proton collisions at using the ATLAS detector

Authors

Morad Aaboud,Georges Aad,Brad Abbott,Ovsat Abdinov,Baptiste Abeloos,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Shunsuke Adachi,C Adam Bourdarios,Leszek Adamczyk,Jahred Adelman,Michael Adersberger,Tim Adye,AA Affolder,Yoav Afik,Catalin Agheorghiesei,JA Aguilar-Saavedra,Faig Ahmadov,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Gian Luigi Alberghi,Justin Albert,Pietro Albicocco,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Gideon Alexander,Theodoros Alexopoulos,Muhammad Alhroob,Babar Ali,Gianluca Alimonti,John Alison,Steven Patrick Alkire,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Alejandro Alonso,Francisco Alonso,Cristiano Alpigiani,Azzah Aziz Alshehri,MI Alstaty,B Alvarez Gonzalez,D Álvarez Piqueras,MG Alviggi,Brian Thomas Amadio,Y Amaral Coutinho,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Christos Anastopoulos,Lucian Stefan Ancu,Nansi Andari,Timothy Andeen,Christoph Falk Anders,John Kenneth Anders,KJ Anderson,Attilio Andreazza,V Andrei,Stylianos Angelidakis,Ivan Angelozzi,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,L Aperio Bella,Giorgi Arabidze,Yasuo Arai,JP Araque,V Araujo Ferraz,R Araujo Pereira,ATH Arce,Rose Elisabeth Ardell,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,Aaron James Armbruster,Lewis James Armitage,Olivier Arnaez,Hannah Arnold,Miguel Arratia,Ozan Arslan,Andrei Artamonov,Giacomo Artoni,Sebastian Artz,Shoji Asai,Nedaa Asbah,Adi Ashkenazi,Eleni Myrto Asimakopoulou,Lily Asquith,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Kamil Augsten,Giuseppe Avolio,R Avramidou,Bradley Axen,Mohamad Kassem Ayoub,Georges Azuelos,AE Baas,Matthew John Baca,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,JT Baines,Milena Bajic,OK Baker,Pepijn Johannes Bakker,D Bakshi Gupta,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Elzbieta Banas,Anjishnu Bandyopadhyay,Sw Banerjee,AAE Bannoura,Liron Barak,William Mickael Barbe,Elisabetta Luigia Barberio,Dario Barberis,Marlon Barbero,Teresa Barillari,M-S Barisits,J Barkeloo

Journal

The European Physical Journal C

Published Date

2020/12

The jet energy scale, jet energy resolution, and their systematic uncertainties are measured for jets reconstructed with the ATLAS detector in 2012 using proton–proton data produced at a centre-of-mass energy of 8 TeV with an integrated luminosity of . Jets are reconstructed from clusters of energy depositions in the ATLAS calorimeters using the anti- algorithm. A jet calibration scheme is applied in multiple steps, each addressing specific effects including mitigation of contributions from additional proton–proton collisions, loss of energy in dead material, calorimeter non-compensation, angular biases and other global jet effects. The final calibration step uses several in situ techniques and corrects for residual effects not captured by the initial calibration. These analyses measure both the jet energy scale and resolution by exploiting the transverse momentum balance in  + jet, Z + jet, dijet, and multijet events. A statistical …

A search for the Zγ decay mode of the Higgs boson in pp collisions at s= 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas

Journal

Physics Letters B

Published Date

2020/10/10

A search for the Zγ decay of the Higgs boson, with Z boson decays into pairs of electrons or muons is presented. The analysis uses proton–proton collision data at s= 13 TeV corresponding to an integrated luminosity of 139 fb− 1 recorded by the ATLAS detector at the Large Hadron Collider. The observed data are consistent with the expected background with a p-value of 1.3%. An upper limit at 95% confidence level on the production cross-section times the branching ratio for p p→ H→ Z γ is set at 3.6 times the Standard Model prediction while 2.6 times is expected in the presence of the Standard Model Higgs boson. The best-fit value for the signal yield normalised to the Standard Model prediction is 2.0− 0.9+ 1.0 where the statistical component of the uncertainty is dominant.

Search for Higgs boson decays into two new low-mass spin-0 particles in the channel with the ATLAS detector using collisions at

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas

Journal

Physical Review D

Published Date

2020/12/7

This paper describes a search for beyond the Standard Model decays of the Higgs boson into a pair of new spin-0 particles subsequently decaying into b-quark pairs, H→ a a→(b b)(b b), using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider at center-of-mass energy s= 13 TeV. This search focuses on the range 15 GeV≤ m a≤ 30 GeV, where the decay products are collimated; it is complementary to a previous search in the same final state targeting the range 20 GeV≤ m a≤ 60 GeV, where the decay products are well separated. A novel strategy for the identification of the a→ b b decays is deployed to enhance the efficiency for topologies with small separation angles. The search is performed with 36 fb− 1 of integrated luminosity collected in 2015 and 2016 and sets upper limits on the production cross section of H→ a a→(b b)(b b), where the Higgs boson is produced in …

Measurements of inclusive and differential cross-sections of combined and tWγ production in the eμ channel at 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek

Journal

Journal of High Energy Physics

Published Date

2020/9

Inclusive and differential cross-sections for the production of top quarks in association with a photon are measured with proton-proton collision data corresponding to an integrated luminosity of 139 fb− 1. The data were collected by the ATLAS detector at the LHC during Run 2 between 2015 and 2018 at a centre-of-mass energy of 13 TeV. The measurements are performed in a fiducial volume defined at parton level. Events with exactly one photon, one electron and one muon of opposite sign, and at least two jets, of which at least one is b-tagged, are selected. The fiducial cross-section is measured to be fb. Differential cross-sections as functions of several observables are compared with state-of-the-art Monte Carlo simulations and next-to-leading-order theoretical calculations. These include cross-sections as functions of photon kinematic variables, angular variables related to the photon and the leptons, and …

Search for pairs of scalar leptoquarks decaying into quarks and electrons or muons in = 13 TeV pp collisions with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek

Journal

Journal of High Energy Physics

Published Date

2020/10

A search for new-physics resonances decaying into a lepton and a jet performed by the ATLAS experiment is presented. Scalar leptoquarks pair-produced in pp collisions at= 13 TeV at the Large Hadron Collider are considered using an integrated luminosity of 139 fb− 1, corresponding to the full Run 2 dataset. They are searched for in events with two electrons or two muons and two or more jets, including jets identified as arising from the fragmentation of c-or b-quarks. The observed yield in each channel is consistent with the Standard Model background expectation. Leptoquarks with masses below 1.8 TeV and 1.7 TeV are excluded in the electron and muon channels, respectively, assuming a branching ratio into a charged lepton and a quark of 100%, with minimal dependence on the quark flavour. Upper limits on the aforementioned branching ratio are also given as a function of the leptoquark mass.

Evidence for production in the multilepton final state in proton–proton collisions at   with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,K Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

The European Physical Journal C

Published Date

2020/11

A search is presented for four-top-quark production using an integrated luminosity of 139 fb of proton–proton collision data at a centre-of-mass energy of collected by the ATLAS detector at the LHC. Events are selected if they contain a same-sign lepton pair or at least three leptons (electrons or muons). Jet multiplicity, jet flavour and event kinematics are used to separate signal from the background through a multivariate discriminant, and dedicated control regions are used to constrain the dominant backgrounds. The four-top-quark production cross section is measured to be  fb. This corresponds to an observed (expected) significance with respect to the background-only hypothesis of 4.3 (2.4) standard deviations and provides evidence for this process.

Alignment of the ATLAS inner detector in Run 2

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek

Journal

The European Physical Journal C

Published Date

2020/12

The performance of the ATLAS Inner Detector alignment has been studied using pp collision data at collected by the ATLAS experiment during Run 2 (2015–2018) of the Large Hadron Collider (LHC). The goal of the detector alignment is to determine the detector geometry as accurately as possible and correct for time-dependent movements. The Inner Detector alignment is based on the minimization of track-hit residuals in a sequence of hierarchical levels, from global mechanical assembly structures to local sensors. Subsequent levels have increasing numbers of degrees of freedom; in total there are almost 750,000. The alignment determines detector geometry on both short and long timescales, where short timescales describe movements within an LHC fill. The performance and possible track parameter biases originating from systematic detector deformations are evaluated. Momentum biases are …

Search for pair production of scalar leptoquarks decaying into first- or second-generation leptons and top quarks in proton-proton collisions at = 13 TeV with the …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,EM Baldin,Petr Balek,Fabrice Balli

Journal

The European Physical Journal C

Published Date

2021/4

A search for pair production of scalar leptoquarks, each decaying into either an electron or a muon and a top quark, is presented. This is the first leptoquark search using ATLAS data to investigate top-philic cross-generational couplings that could provide explanations for recently observed anomalies in B meson decays. This analysis targets high leptoquark masses which cause the decay products of each resultant top quark to be contained within a single high- large-radius jet. The full Run 2 dataset is exploited, consisting of of data collected from proton–proton collisions at from 2015 to 2018 with the ATLAS detector at the CERN Large Hadron Collider. In the absence of any significant deviation from the background expectation, lower limits on the leptoquark masses are set at and for the electron and muon channel, respectively.

First results on ProtoDUNE-SP liquid argon time projection chamber performance from a beam test at the CERN Neutrino Platform

Authors

B Abi,A Abed Abud,R Acciarri,MA Acero,G Adamov,M Adamowski,D Adams,P Adrien,M Adinolfi,Z Ahmad,J Ahmed,T Alion,S Alonso Monsalve,C Alt,J Anderson,C Andreopoulos,MP Andrews,F Andrianala,S Andringa,A Ankowski,M Antonova,S Antusch,A Aranda-Fernandez,A Ariga,LO Arnold,MA Arroyave,J Asaadi,A Aurisano,V Aushev,D Autiero,F Azfar,H Back,JJ Back,C Backhouse,P Baesso,L Bagby,R Bajou,S Balasubramanian,P Baldi,B Bambah,F Barao,G Barenboim,GJ Barker,W Barkhouse,C Barnes,G Barr,J Barranco Monarca,N Barros,JL Barrow,A Bashyal,V Basque,F Bay,JL Bazo Alba,JF Beacom,E Bechetoille,B Behera,L Bellantoni,G Bellettini,V Bellini,O Beltramello,D Belver,N Benekos,F Bento Neves,J Berger,S Berkman,P Bernardini,RM Berner,H Berns,S Bertolucci,M Betancourt,Y Bezawada,M Bhattacharjee,B Bhuyan,S Biagi,J Bian,M Biassoni,K Biery,B Bilki,M Bishai,A Bitadze,A Blake,B Blanco Siffert,FDM Blaszczyk,GC Blazey,E Blucher,J Boissevain,S Bolognesi,T Bolton,M Bonesini,M Bongrand,F Bonini,A Booth,C Booth,S Bordoni,A Borkum,T Boschi,N Bostan,P Bour,SB Boyd,D Boyden,J Bracinik,D Braga,D Brailsford,A Brandt,J Bremer,C Brew,E Brianne,SJ Brice,C Brizzolari,C Bromberg,G Brooijmans,J Brooke,A Bross,G Brunetti,N Buchanan,H Budd,D Caiulo,P Calafiura,J Calcutt,M Calin,S Calvez,E Calvo,L Camilleri,A Caminata,M Campanelli,D Caratelli,G Carini,B Carlus,P Carniti,I Caro Terrazas,H Carranza,A Castillo,C Castromonte,C Cattadori,F Cavalier,F Cavanna,S Centro,G Cerati,A Cervelli,A Cervera Villanueva,M Chalifour,C Chang,E Chardonnet,N Charitonidis,A Chatterjee,S Chattopadhyay,P Chatzidaki,J Chaves,H Chen,M Chen

Journal

Journal of Instrumentation

Published Date

2020/12/3

The Deep Underground Neutrino Experiment (DUNE)[1] is a next-generation, long-baseline neutrino oscillation experiment, with a near detector at Fermilab and a far detector located at the 4850 ft level of Sanford Underground Research Facility (SURF), in Lead, South Dakota, USA, 1285 km from the neutrino production target. The neutrino detectors at the DUNE far site will be housed inside four cryostats, each of which will contain 17.5 kt of liquid argon (LAr). The first detector to be constructed will be a single-phase time projection chamber (TPC), similar to, but a factor of 25 more massive than the pioneering T600 detector built by the ICARUS

Search for direct production of electroweakinos in final states with missing transverse momentum and a Higgs boson decaying into photons in pp collisions at $$\sqrt {s} $$= 13 …

Authors

Georges Aad,B Abbott,Kira Abeling,Nils Julius Abicht,SH Abidi,Asmaa Aboulhorma,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,C Adam Bourdarios,Leszek Adamczyk,SV Addepalli,MJ Addison,Jahred Adelman,Aytul Adiguzel,Tim Adye,AA Affolder,Yoav Afik,Merve Nazlim Agaras,Jinky Agarwala,Anamika Aggarwal,Catalin Agheorghiesei,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Sudha Ahuja,Xiaocong Ai,Giulio Aielli,Arya Aikot,M Ait Tamlihat,Brahim Aitbenchikh,Iakov Aizenberg,Melike Akbiyik,TPA Åkesson,AV Akimov,Daiya Akiyama,Nilima Nilesh Akolkar,Sina Aktas,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,Pietro Albicocco,Guillaume Lucas Albouy,Sara Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Fabrizio Alfonsi,Malte Algren,Muhammad Alhroob,Babar Ali,HMJ Ali,Shahzad Ali,Samuel William Alibocus,Malik Aliev,Gianluca Alimonti,Wael Alkakhi,Corentin Allaire,BMM Allbrooke,Julia Frances Allen,CA Allendes Flores,Philip Patrick Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,M Alvarez Estevez,A Alvarez Fernandez,M Alves Cardoso,MG Alviggi,Mohamed Aly,Y Amaral Coutinho,Alessandro Ambler,Christoph Amelung,Maximilian Amerl,CG Ames,Dante Amidei,SP Amor Dos Santos,Kieran Robert Amos,Viktor Ananiev,Christos Anastopoulos,T Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,Fabio Anulli,Masato Aoki,Takumi Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Christian Appelt,Aram Apyan,N Aranzabal,SJ Arbiol Val,Chiara Arcangeletti,ATH Arce,Eloisa Arena,Jean-Francois Arguin,Spyros Argyropoulos,J-H Arling,Olivier Arnaez,Hannah Arnold,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Nedaa Alexandra Asbah,Jihad Assahsah,K Assamagan,Robert Astalos,S Atashi,Ryan Justin Atkin,M Atkinson,Hicham Atmani,PA Atmasiddha,Kamil Augsten,Silvia Auricchio,AD Auriol,Volker Andreas Austrup,Giuseppe Avolio,Konstantinos Axiotis,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Alexander Bachiu,F Backman,Anthony Badea,Tamas Marton Baer,Paolo Bagnaia,Marzieh Bahmani,AJ Bailey,VR Bailey,JT Baines,Luke Baines,OK Baker,Evelin Bakos,D Bakshi Gupta,Veena Balakrishnan,Rahul Balasubramanian

Journal

Journal of High Energy Physics

Published Date

2023/12

Searches for electroweak production of wino-like chargino pairs,, and of wino-like chargino and next-to-lightest neutralino,, are presented. The models explored assume that the charginos decay into a W boson and the lightest neutralino,. The next-to-lightest neutralinos are degenerate in mass with the chargino and decay to and either a Z or a Higgs boson, or. The searches exploit the presence of a single isolated lepton and missing transverse momentum from the W boson decay products and the lightest neutralinos, and the presence of jets from hadronically decaying Z or W bosons or from the Higgs boson decaying into a pair of b-quarks. The searches use 139 fb− 1 of= 13 TeV proton-proton collisions data collected by the ATLAS detector at the Large Hadron Collider between 2015 and 2018. No deviations from the Standard Model expectations are found, and 95% confidence level exclusion limits …

Search for top squarks in events with a Higgs or Z boson using 139 fb of pp collision data at  TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,TPA Åkesson,Ece Akilli,AV Akimov,K Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas

Journal

The European Physical Journal C

Published Date

2020/11

This paper presents a search for direct top squark pair production in events with missing transverse momentum plus either a pair of jets consistent with Standard Model Higgs boson decay into b-quarks or a same-flavour opposite-sign dilepton pair with an invariant mass consistent with a Z boson. The analysis is performed using the proton–proton collision data at TeV collected with the ATLAS detector during the LHC Run-2, corresponding to an integrated luminosity of 139 fb. No excess is observed in the data above the Standard Model predictions. The results are interpreted in simplified models featuring direct production of pairs of either the lighter top squark () or the heavier top squark (), excluding at 95% confidence level and masses up to about 1220 and 875 GeV, respectively.

Search for Higgs Boson Decays into a Boson and a Light Hadronically Decaying Resonance Using 13 TeV Collision Data from the ATLAS Detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz

Journal

Physical review letters

Published Date

2020/11/25

A search for Higgs boson decays into a Z boson and a light resonance in two-lepton plus jet events is performed, using a p p collision dataset with an integrated luminosity of 139 fb− 1 collected at s= 13 TeV by the ATLAS experiment at the CERN LHC. The resonance considered is a light boson with a mass below 4 GeV from a possible extended scalar sector or a charmonium state. Multivariate discriminants are used for the event selection and for evaluating the mass of the light resonance. No excess of events above the expected background is found. Observed (expected) 95% confidence-level upper limits are set on the Higgs boson production cross section times branching fraction to a Z boson and the signal resonance, with values in the range 17–340 pb (16− 5+ 6–32 0− 90+ 130 pb) for the different light spin-0 boson mass and branching fraction hypotheses, and with values of 110 and 100 pb (100− 30+ 40 …

Operation of the ATLAS trigger system in Run 2

Authors

Atlas Collaboration

Journal

Journal of Instrumentation

Published Date

2020/10/2

The ATLAS experiment at the Large Hadron Collider employs a two-level trigger system to record data at an average rate of 1 kHz from physics collisions, starting from an initial bunch crossing rate of 40 MHz. During the LHC Run 2 (2015–2018), the ATLAS trigger system operated successfully with excellent performance and flexibility by adapting to the various run conditions encountered and has been vital for the ATLAS Run-2 physics programme. For proton-proton running, approximately 1500 individual event selections were included in a trigger menu which specified the physics signatures and selection algorithms used for the data-taking, and the allocated event rate and bandwidth. The trigger menu must reflect the physics goals for a given data collection period, taking into account the instantaneous luminosity of the LHC and limitations from the ATLAS detector readout, online processing farm, and offline …

Search for Heavy Resonances Decaying into a Photon and a Hadronically Decaying Higgs Boson in Collisions at with the ATLAS Detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,Ossama Abouzeid,Nicola Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,Claire Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,Tony Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,Juan Antonio Aguilar Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,Torsten Paul Ake Akesson,Ece Akilli,Andrei Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,Maria Josefina Alconada Verzini,Sara Caroline Alderweireldt,Martin Aleksa,Igor Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,Benedict Allbrooke,Benjamin William Allen,Phillip Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,Elio Alunno Camelia,Manuel Alvarez Estevez,Mariagrazia Alviggi,Yara Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,Dante Eric Amidei,Susana Patricia Amor dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,George Victor Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,Alexey Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,Daniel Joseph Antrim,Fabio Anulli,Masato Aoki,Javier Alberto Aparisi Pozo,Marco Aparo,Ludovica Aperio Bella,Nordin Aranzabal Barrio,Victor Araujo Ferraz,Rodrigo Araujo Pereira,Chiara Arcangeletti,Ayana Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,Jan-Hendrik Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,Zulit Paola Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,Sina Baluch Bahrasemani,Adam Bailey,Virginia Ruth Bailey,John Baines,Christos Bakalis,Keith Baker,Pepijn Johannes Bakker,Evelin Bakos,Debottam Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,Evgenii Baldin,Petr Balek

Published Date

2020/9/8

This Letter presents a search for the production of new heavy resonances decaying into a Higgs boson and a photon using proton-proton collision data at sqrt[s]=13  TeV collected by the ATLAS detector at the LHC. The data correspond to an integrated luminosity of 139  fb^{-1}. The analysis is performed by reconstructing hadronically decaying Higgs boson (H→bb[over ¯]) candidates as single large-radius jets. A novel algorithm using information about the jet constituents in the center-of-mass frame of the jet is implemented to identify the two b quarks in the single jet. No significant excess of events is observed above the expected background. Upper limits are set on the production cross-section times branching fraction for narrow spin-1 resonances decaying into a Higgs boson and a photon in the resonance mass range from 0.7 to 4 TeV, cross-section times branching fractions are excluded between 11.6 fb and 0.11 fb at a 95% confidence level.

Search for new phenomena in final states with large jet multiplicities and missing transverse momentum using = 13 TeV proton-proton collisions recorded by …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,A Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,NL Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,N Aranzabal Barrio,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz,Elzbieta Banas

Journal

Journal of High Energy Physics

Published Date

2020/10

Results of a search for new particles decaying into eight or more jets and moderate missing transverse momentum are presented. The analysis uses 139 fb− 1 of proton-proton collision data at= 13 TeV collected by the ATLAS experiment at the Large Hadron Collider between 2015 and 2018. The selection rejects events containing isolated electrons or muons, and makes requirements according to the number of b-tagged jets and the scalar sum of masses of large-radius jets. The search extends previous analyses both in using a larger dataset and by employing improved jet and missing transverse momentum reconstruction methods which more cleanly separate signal from background processes. No evidence for physics beyond the Standard Model is found. The results are interpreted in the context of supersymmetry-inspired simplified models, significantly extending the limits on the gluino mass in those models …

Reconstruction and identification of boosted di-τ systems in a search for Higgs boson pairs using 13 TeV proton-proton collision data in ATLAS

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,OS AbouZeid,Nadine L Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,C Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,AA Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,JA Aguilar-Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,TPA Åkesson,Ece Akilli,AV Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,MJ Alconada Verzini,S Alderweireldt,Martin Aleksa,IN Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,BMM Allbrooke,Benjamin William Allen,PP Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,E Alunno Camelia,M Alvarez Estevez,MG Alviggi,Y Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,D Amidei,SP Amor Dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,V Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,AV Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,DJA Antrim,Fabio Anulli,Masato Aoki,JA Aparisi Pozo,MA Aparo,L Aperio Bella,Nordin Aranzabal,V Araujo Ferraz,R Araujo Pereira,Chiara Arcangeletti,ATH Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,J-H Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,ZP Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,H Bahrasemani,AJ Bailey,Virginia Ruth Bailey,JT Baines,Christos Bakalis,OK Baker,Pepijn Johannes Bakker,Evelin Bakos,D Bakshi Gupta,Shyam Balaji,EM Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz

Journal

Journal of High Energy Physics

Published Date

2020/11

In this paper, a new technique for reconstructing and identifying hadronically decaying τ+ τ− pairs with a large Lorentz boost, referred to as the di-τ tagger, is developed and used for the first time in the ATLAS experiment at the Large Hadron Collider. A benchmark di-τ tagging selection is employed in the search for resonant Higgs boson pair production, where one Higgs boson decays into a boosted pair and the other into a boosted τ+ τ− pair, with two hadronically decaying τ-leptons in the final state. Using 139 fb− 1 of proton-proton collision data recorded at a centre-of-mass energy of 13 TeV, the efficiency of the di-τ tagger is determined and the background with quark-or gluon-initiated jets misidentified as di-τ objects is estimated. The search for a heavy, narrow, scalar resonance produced via gluon-gluon fusion and decaying into two Higgs bosons is carried out in the mass range 1–3 TeV using the same …

Search for resonances in fully hadronic final states in pp collisions at = 13 TeV with the ATLAS detector

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,Ossama Abouzeid,Nicola Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,Claire Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Michael Adersberger,Aytul Adiguzel,Sofia Adorni,Tim Adye,Tony Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,Juan Antonio Aguilar Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Torsten Paul Ake Akesson,Ece Akilli,Andrei Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,Maria Josefina Alconada Verzini,Sara Caroline Alderweireldt,Martin Aleksa,Igor Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,Benedict Allbrooke,Benjamin William Allen,Phillip Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,Elio Alunno Camelia,Manuel Alvarez Estevez,Mariagrazia Alviggi,Yara Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,Dante Eric Amidei,Susana Patricia Amor dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,George Victor Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,Alexey Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,Daniel Joseph Antrim,Fabio Anulli,Masato Aoki,Javier Alberto Aparisi Pozo,Marco Aparo,Ludovica Aperio Bella,Nordin Aranzabal Barrio,Victor Araujo Ferraz,Rodrigo Araujo Pereira,Chiara Arcangeletti,Ayana Arce,Francisco Anuar Arduh,Jean-Francois Arguin,Spyridon Argyropoulos,Jan-Hendrik Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,Zulit Paola Arrubarrena Tame,Giacomo Artoni,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Henri Bachacou,Konstantinos Bachas,Moritz Backes,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,Sina Baluch Bahrasemani,Adam Bailey,Virginia Ruth Bailey,John Baines,Christos Bakalis,Keith Baker,Pepijn Johannes Bakker,Evelin Bakos,Debottam Bakshi Gupta,Shyam Balaji,Evgenii Baldin,Petr Balek,Fabrice Balli,William Keaton Balunas,Johannes Balz

Published Date

2020/5/26

This paper presents a search for new heavy particles decaying into a pair of top quarks using 139 fb-1 of proton-proton collision data recorded at a centre-of-mass energy of

Search for a heavy Higgs boson decaying into a boson and another heavy Higgs boson in the and final states in collisions at = 13 TeV with the …

Authors

Georges Aad,Brad Abbott,Dale Charles Abbott,Adam Abed Abud,Kira Abeling,Deshan Kavishka Abhayasinghe,Syed Haider Abidi,Ossama Abouzeid,Nicola Abraham,Halina Abramowicz,Henso Abreu,Yiming Abulaiti,Bobby Samir Acharya,Baida Achkar,Lennart Adam,Claire Adam Bourdarios,Leszek Adamczyk,Lukas Adamek,Jahred Adelman,Aytul Adiguzel,Sofia Adorni,Tim Adye,Tony Affolder,Yoav Afik,Christina Agapopoulou,Merve Nazlim Agaras,Anamika Aggarwal,Catalin Agheorghiesei,Juan Antonio Aguilar Saavedra,Ammara Ahmad,Faig Ahmadov,Waleed Syed Ahmed,Xiaocong Ai,Giulio Aielli,Shunichi Akatsuka,Melike Akbiyik,Torsten Paul Ake Akesson,Ece Akilli,Andrei Akimov,Konie Al Khoury,Gian Luigi Alberghi,Justin Albert,Maria Josefina Alconada Verzini,Sara Caroline Alderweireldt,Martin Aleksa,Igor Aleksandrov,Calin Alexa,Theodoros Alexopoulos,Alice Alfonsi,Fabrizio Alfonsi,Muhammad Alhroob,Babar Ali,Shahzad Ali,Malik Aliev,Gianluca Alimonti,Corentin Allaire,Benedict Allbrooke,Benjamin William Allen,Phillip Allport,Alberto Aloisio,Francisco Alonso,Cristiano Alpigiani,Elio Alunno Camelia,Manuel Alvarez Estevez,Mariagrazia Alviggi,Yara Amaral Coutinho,Alessandro Ambler,Luca Ambroz,Christoph Amelung,Dante Eric Amidei,Susana Patricia Amor dos Santos,Simone Amoroso,Cherifa Sabrina Amrouche,Fenfen An,Christos Anastopoulos,Nansi Andari,Timothy Andeen,John Kenneth Anders,Stefio Yosse Andrean,Attilio Andreazza,George Victor Andrei,Christopher Ryan Anelli,Stylianos Angelidakis,Aaron Angerami,Alexey Anisenkov,Alberto Annovi,Claire Antel,Matthew Thomas Anthony,Egor Antipov,Mario Antonelli,Daniel Joseph Antrim,Fabio Anulli,Masato Aoki,Javier Alberto Aparisi Pozo,Marco Aparo,Ludovica Aperio Bella,Nordin Aranzabal,Victor Araujo Ferraz,Rodrigo Araujo Pereira,Chiara Arcangeletti,Ayana Arce,Jean-Francois Arguin,Spyridon Argyropoulos,Jan-Hendrik Arling,Aaron James Armbruster,Alexander Armstrong,Olivier Arnaez,Hannah Arnold,Zulit Paola Arrubarrena Tame,Giacomo Artoni,Haruka Asada,Kanae Asai,Shoji Asai,Thanawat Asawatavonvanich,Nedaa Asbah,Eleni Myrto Asimakopoulou,Lily Asquith,Jihad Assahsah,Ketevi Assamagan,Robert Astalos,Ryan Justin Atkin,Markus Atkinson,Naim Bora Atlay,Hicham Atmani,Prachi Arvind Atmasiddha,Kamil Augsten,Volker Andreas Austrup,Giuseppe Avolio,Mohamad Kassem Ayoub,Georges Azuelos,Dominik Babal,Henri Bachacou,Konstantinos Bachas,Filip Backman,Paolo Bagnaia,Marzieh Bahmani,Sina Baluch Bahrasemani,Adam Bailey,Virginia Ruth Bailey,John Baines,Christos Bakalis,Keith Baker,Pepijn Johannes Bakker,Evelin Bakos,Debottam Bakshi Gupta,Shyam Balaji,Rahul Balasubramanian,Evgenii Baldin,Petr Balek,Fabrice Balli

Published Date

2020/12/1

; Wosiek, B.; Wozniak, K.; Wraight, K.; Wu, SL; Wu, X.; Wu, Y.; Wuerzinger, J.; Wyatt, TR; Wynne, B.; Xella, S.; Xia, L.; Xiang, J.; Xiao, X.; Xie, X.; Xiotidis, I.; Xu, D.; Xu, H.; Xu, H.; Xu, L.; Xu, R.; Xu, T.; Xu, W.; Xu, Y.; Xu, Z.; Xu, Z.; Yabsley, B.

Cognitive and clinical outcome measures for Alzheimer's disease prevention trials in adults with Down syndrome: The conduct of clinical investigations in the Down syndrome …

Authors

Andre Strydom,Asaad Baksh,Rosalyn Hithersay,Andrew J Aschenbrenner,Judith Jaeger,Ben Carter,Peter A Wijeratne,Daniel C Alexander,Jason Hassenstab,Horizon21 Consortium

Journal

Alzheimer's & Dementia

Published Date

2020/12

Background Adults with Down syndrome (DS) are at ultra‐high risk for developing Alzheimer’s disease (AD) due to APP gene triplication on chromosome 21. There is interest in conducting trials of treatment that can delay or prevent onset of disease in at‐risk individuals with DS. Reliable outcome measures are required to demonstrate clinical benefit of treatment in a population with premorbid cognitive impairments that affect their performance on cognitive outcome measures. We aimed to identify the most efficient clinical and cognitive outcomes for prevention trials of AD in DS. Methods Analysis of cognitive data based on different test batteries from several recent longitudinal cohort studies of AD in DS in Europe and the US (n >300 with 2 years of follow‐up data), using staging and E‐Max models and other statistical methods. Results The age range within which cognitive decline can be first reliably observed in …

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Characterizing developing executive functions in the first 1000 days in South Africa and Malawi: The Khula Study

Investigating the Role of Bilateral Symmetry for Inpainting Brain MRI

Distinct spatiotemporal atrophy patterns in corticobasal syndrome are associated with different underlying pathologies

The temporal event-based model: Learning event timelines in progressive diseases

Subtype and stage inference with timescales

Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning

A data-driven study of Alzheimer's disease related amyloid and tau pathology progression

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