Rafael Lozano

Rafael Lozano

University of Washington

H-index: 114

North America-United States

About Rafael Lozano

Rafael Lozano, With an exceptional h-index of 114 and a recent h-index of 92 (since 2020), a distinguished researcher at University of Washington, specializes in the field of Health Metrics, Global Health, Burden of Disease, Latin America, Mexico.

Rafael Lozano Information

University

University of Washington

Position

Professor Institute for Health Metrics and Evaluation

Citations(all)

232985

Citations(since 2020)

133054

Cited By

141246

hIndex(all)

114

hIndex(since 2020)

92

i10Index(all)

254

i10Index(since 2020)

185

Email

University Profile Page

University of Washington

Rafael Lozano Skills & Research Interests

Health Metrics

Global Health

Burden of Disease

Latin America

Mexico

Top articles of Rafael Lozano

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in …

Authors

GBD

Journal

The Lancet

Published Date

2024

BackgroundDetailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are …

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the …

Authors

Mohsen Naghavi,Kanyin Liane Ong,Amirali Aali,Hazim S Ababneh,Yohannes Habtegiorgis Abate,Cristiana Abbafati,Rouzbeh Abbasgholizadeh,Mohammadreza Abbasian,Mohsen Abbasi-Kangevari,Hedayat Abbastabar,Samar Abd ElHafeez,Michael Abdelmasseh,Sherief Abd-Elsalam,Ahmed Abdelwahab,Mohammad Abdollahi,Mohammad-Amin Abdollahifar,Meriem Abdoun,Deldar Morad Abdulah,Auwal Abdullahi,Mesfin Abebe,Samrawit Shawel Abebe,Aidin Abedi,Kedir Hussein Abegaz,ES Abhilash,Hassan Abidi,Olumide Abiodun,Richard Gyan Aboagye,Hassan Abolhassani,Meysam Abolmaali,Mohamed Abouzid,Girma Beressa Aboye,Lucas Guimarães Abreu,Woldu Aberhe Abrha,Dariush Abtahi,Samir Abu Rumeileh,Hasan Abualruz,Bilyaminu Abubakar,Eman Abu-Gharbieh,Niveen ME Abu-Rmeileh,Salahdein Aburuz,Ahmed Abu-Zaid,Manfred Mario Kokou Accrombessi,Tadele Girum Adal,Abdu A Adamu,Isaac Yeboah Addo,Giovanni Addolorato,Akindele Olupelumi Adebiyi,Victor Adekanmbi,Abiola Victor Adepoju,Charles Oluwaseun Adetunji,Juliana Bunmi Adetunji,Temitayo Esther Adeyeoluwa,Daniel Adedayo Adeyinka,Olorunsola Israel Adeyomoye,Biruk Adie Adie Admass,Qorinah Estiningtyas Sakilah Adnani,Saryia Adra,Aanuoluwapo Adeyimika Afolabi,Muhammad Sohail Afzal,Saira Afzal,Suneth Buddhika Agampodi,Pradyumna Agasthi,Manik Aggarwal,Shahin Aghamiri,Feleke Doyore Agide,Antonella Agodi,Anurag Agrawal,Williams Agyemang-Duah,Bright Opoku Ahinkorah,Aqeel Ahmad,Danish Ahmad,Firdos Ahmad,Muayyad M Ahmad,Sajjad Ahmad,Shahzaib Ahmad,Tauseef Ahmad,Keivan Ahmadi,Amir Mahmoud Ahmadzade,Ali Ahmed,Ayman Ahmed,Haroon Ahmed,Luai A Ahmed,Mehrunnisha Sharif Ahmed,Meqdad Saleh Ahmed,Muktar Beshir Ahmed,Syed Anees Ahmed,Marjan Ajami,Budi Aji,Essona Matatom Akara,Hossein Akbarialiabad,Karolina Akinosoglou,Tomi Akinyemiju,Mohammed Ahmed Akkaif,Samuel Akyirem,Hanadi Al Hamad,Syed Mahfuz Al Hasan,Fares Alahdab,Samer O Alalalmeh,Tariq A Alalwan,Ziyad Al-Aly,Khurshid Alam,Manjurul Alam,Noore Alam,Rasmieh Mustafa Al-amer,Fahad Mashhour Alanezi,Turki M Alanzi,Sayer Al-Azzam,Almaza Albakri,Mohammed Albashtawy,Mohammad T AlBataineh,Jacqueline Elizabeth Alcalde-Rabanal,Khalifah A Aldawsari,Wafa A Aldhaleei,Robert W Aldridge,Haileselasie Berhane Alema,Mulubirhan Assefa Alemayohu,Sharifullah Alemi,Yihun Mulugeta Alemu,Adel Ali Saeed Al-Gheethi,Khalid F Alhabib,Fadwa Alhalaiqa Naji Alhalaiqa,Mohammed Khaled Al-Hanawi,Abid Ali,Amjad Ali,Liaqat Ali,Mohammed Usman Ali,Rafat Ali,Shahid Ali,Syed Shujait Shujait Ali,Gianfranco Alicandro,Sheikh Mohammad Alif,Reyhaneh Alikhani,Yousef Alimohamadi,Ahmednur Adem Aliyi,Mohammad AM Aljasir,Syed Mohamed Aljunid,François Alla,Peter Allebeck,Sabah Al-Marwani,Sadeq Ali Ali Al-Maweri,Joseph Uy Almazan,Hesham M Al-Mekhlafi,Louay Almidani,Omar Almidani,Mahmoud A Alomari,Basem Al-Omari,Jordi Alonso,Jaber S Alqahtani,Shehabaldin Alqalyoobi,Ahmed Yaseen Alqutaibi

Journal

The Lancet

Published Date

2024/4/3

BackgroundRegular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations.MethodsThe Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational …

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the …

Authors

Austin E Schumacher,Hmwe Hmwe Kyu,Amirali Aali,Cristiana Abbafati,Jaffar Abbas,Rouzbeh Abbasgholizadeh,Madineh Akram Abbasi,Mohammadreza Abbasian,Samar Abd ElHafeez,Michael Abdelmasseh,Sherief Abd-Elsalam,Ahmed Abdelwahab,Mohammad Abdollahi,Meriem Abdoun,Auwal Abdullahi,Ame Mehadi Abdurehman,Mesfin Abebe,Aidin Abedi,Armita Abedi,Tadesse M Abegaz,Roberto Ariel Abeldaño Zuñiga,ES Abhilash,Olugbenga Olusola Abiodun,Richard Gyan Aboagye,Hassan Abolhassani,Mohamed Abouzid,Lucas Guimarães Abreu,Woldu Aberhe Abrha,Michael RM Abrigo,Dariush Abtahi,Samir Abu Rumeileh,Niveen ME Abu-Rmeileh,Salahdein Aburuz,Ahmed Abu-Zaid,Juan Manuel Acuna,Tim Adair,Isaac Yeboah Addo,Oladimeji M Adebayo,Oyelola A Adegboye,Victor Adekanmbi,Bashir Aden,Abiola Victor Adepoju,Charles Oluwaseun Adetunji,Temitayo Esther Adeyeoluwa,Olorunsola Israel Adeyomoye,Rishan Adha,Amin Adibi,Wirawan Adikusuma,Qorinah Estiningtyas Sakilah Adnani,Saryia Adra,Abel Afework,Aanuoluwapo Adeyimika Afolabi,Ali Afraz,Shadi Afyouni,Saira Afzal,Pradyumna Agasthi,Shahin Aghamiri,Antonella Agodi,Williams Agyemang-Duah,Bright Opoku Ahinkorah,Aqeel Ahmad,Danish Ahmad,Firdos Ahmad,Muayyad M Ahmad,Tauseef Ahmad,Keivan Ahmadi,Amir Mahmoud Ahmadzade,Mohadese Ahmadzade,Ayman Ahmed,Haroon Ahmed,Luai A Ahmed,Muktar Beshir Ahmed,Syed Anees Ahmed,Marjan Ajami,Budi Aji,Olufemi Ajumobi,Gizachew Taddesse Akalu,Essona Matatom Akara,Karolina Akinosoglou,Sreelatha Akkala,Samuel Akyirem,Hanadi Al Hamad,Syed Mahfuz Al Hasan,Ammar Al Homsi,Mohammad Al Qadire,Moein Ala,Timothy Olukunle Aladelusi,Tareq Mohammed Ali AL-Ahdal,Samer O Alalalmeh,Ziyad Al-Aly,Khurshid Alam,Manjurul Alam,Zufishan Alam,Rasmieh Mustafa Al-amer,Fahad Mashhour Alanezi,Turki M Alanzi,Mohammed Albashtawy,Mohammad T AlBataineh,Robert W Aldridge,Sharifullah Alemi,Ayman Al-Eyadhy,Adel Ali Saeed Al-Gheethi,Khalid F Alhabib,Fadwa Alhalaiqa Naji Alhalaiqa,Mohammed Khaled Al-Hanawi,Abid Ali,Akhtar Ali,Beriwan Abdulqadir Ali,Hassam Ali,Mohammed Usman Ali,Rafat Ali,Syed Shujait Shujait Ali,Zahid Ali,Shohreh Alian Samakkhah,Gianfranco Alicandro,Sheikh Mohammad Alif,Mohammad Aligol,Rasoul Alimi,Ahmednur Adem Aliyi,Adel Al-Jumaily,Syed Mohamed Aljunid,Wael Almahmeed,Sabah Al-Marwani,Sadeq Ali Ali Al-Maweri,Joseph Uy Almazan,Hesham M Al-Mekhlafi,Omar Almidani,Mahmoud A Alomari,Nivaldo Alonso,Jaber S Alqahtani,Ahmed Yaseen Alqutaibi,Salman Khalifah Al-Sabah,Awais Altaf,Jaffar A Al-Tawfiq,Khalid A Altirkawi,Farrukh Jawad Alvi,Hassan Alwafi,Yaser Mohammed Al-Worafi,Hany Aly,Karem H Alzoubi,Azmeraw T Amare,Edward Kwabena Ameyaw,Abebe Feyissa Amhare,Tarek Tawfik Amin,Alireza Amindarolzarbi,Javad Aminian Dehkordi,Sohrab Amiri,Hubert Amu,Dickson A Amugsi,Jimoh Amzat

Journal

The Lancet

Published Date

2024/3/11

BackgroundEstimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period.Methods22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 …

A gender-based and quasi-experimental study of the catastrophic and impoverishing health-care expenditures in Mexican households with elderly members, 2000-2020

Authors

Edson Serván-Mori,Emanuel Orozco-Núñez,Carlos M Guerrero-López,J Jaime Miranda,Stephen Jan,Laura Downey,Emma Feeny,Ileana Heredia-Pi,Laura Flamand,Gustavo Nigenda,Robyn Norton,Rafael Lozano

Journal

Health Systems & Reform

Published Date

2023/12/31

Latin America has experienced a rise in noncommunicable diseases (NCDs) which is having repercussions on the structuring of healthcare delivery and social protection for vulnerable populations. We examined catastrophic (CHE) and excessive (EHE, impoverishing and/or catastrophic) health care expenditures in Mexican households with and without elderly members (≥65 years), by gender of head of the households, during 2000–2020. We analyzed pooled cross-sectional data for 380,509 households from eleven rounds of the National Household Income and Expenditure Survey. Male- and female-headed households (MHHs and FHHs) were matched using propensity scores to control for gender bias in systematic differences regarding care-seeking (demand for healthcare) preferences. Adjusted probabilities of positive health expenditures, CHE and EHE were estimated using probit and two-stage probit …

Burden, Incidence, Mortality and Lethality of Maternal Disorders in Mexico 1990-2019: An Analysis for the Global Burden of Disease Study 2019

Authors

Alejandra Montoya,Rafael Lozano,Mario Sanchez-Dominguez,Jimena Fritz,Héctor Lamadrid-Figueroa

Journal

Archives of Medical Research

Published Date

2023/2/1

BackgroundEstimates of the sub-national distribution of maternal disorders in Mexico beyond Maternal Mortality Ratios are scarce. Characterizing the sub-national variation of maternal disorders may make it possible to focus more on interventions and thereby reduce their occurrence in a more meaningful and sustained manner.AimTo analyze and describe the sub-national distribution, magnitude, trends and changes in the contribution of maternal causes to women's loss of health in Mexico from 1990–2019.MethodsUsing estimates from the Global Burden of Disease (GBD) 2019 study, we describe the distribution and trends of maternal mortality ratio (MMR), mortality rate, case-fatality rate and disability-adjusted life years (DALYs) due to maternal causes, at both national and state levels.ResultsBetween 1990 and 2019, DALYs attributable to maternal causes had decreased 59.5%, mortality 63.8%, and incidence …

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Authors

Kanyin Liane Ong,Lauryn K Stafford,Susan A McLaughlin,Edward J Boyko,Stein Emil Vollset,Amanda E Smith,Bronte E Dalton,Joe Duprey,Jessica A Cruz,Hailey Hagins,Paulina A Lindstedt,Amirali Aali,Yohannes Habtegiorgis Abate,Melsew Dagne Abate,Mohammadreza Abbasian,Zeinab Abbasi-Kangevari,Mohsen Abbasi-Kangevari,Samar Abd ElHafeez,Rami Abd-Rabu,Deldar Morad Abdulah,Abu Yousuf Md Abdullah,Vida Abedi,Hassan Abidi,Richard Gyan Aboagye,Hassan Abolhassani,Eman Abu-Gharbieh,Ahmed Abu-Zaid,Tigist Demssew Adane,Denberu Eshetie Adane,Isaac Yeboah Addo,Oyelola A Adegboye,Victor Adekanmbi,Abiola Victor Adepoju,Qorinah Estiningtyas Sakilah Adnani,Rotimi Felix Afolabi,Gina Agarwal,Zahra Babaei Aghdam,Marcela Agudelo-Botero,Constanza Elizabeth Aguilera Arriagada,Williams Agyemang-Duah,Bright Opoku Ahinkorah,Danish Ahmad,Rizwan Ahmad,Sajjad Ahmad,Aqeel Ahmad,Ali Ahmadi,Keivan Ahmadi,Ayman Ahmed,Ali Ahmed,Luai A Ahmed,Syed Anees Ahmed,Marjan Ajami,Rufus Olusola Akinyemi,Hanadi Al Hamad,Syed Mahfuz Al Hasan,Tareq Mohammed Ali AL-Ahdal,Tariq A Alalwan,Ziyad Al-Aly,Mohammad T AlBataineh,Jacqueline Elizabeth Alcalde-Rabanal,Sharifullah Alemi,Hassam Ali,Tahereh Alinia,Syed Mohamed Aljunid,Sami Almustanyir,Rajaa M Al-Raddadi,Nelson Alvis-Guzman,Firehiwot Amare,Edward Kwabena Ameyaw,Sohrab Amiri,Ganiyu Adeniyi Amusa,Catalina Liliana Andrei,Ranjit Mohan Anjana,Adnan Ansar,Golnoosh Ansari,Alireza Ansari-Moghaddam,Anayochukwu Edward Anyasodor,Jalal Arabloo,Aleksandr Y Aravkin,Demelash Areda,Hidayat Arifin,Mesay Arkew,Benedetta Armocida,Johan Ärnlöv,Anton A Artamonov,Judie Arulappan,Raphael Taiwo Aruleba,Ashokan Arumugam,Zahra Aryan,Mulu Tiruneh Asemu,Mohammad Asghari-Jafarabadi,Elaheh Askari,Daniel Asmelash,Thomas Astell-Burt,Mohammad Athar,Seyyed Shamsadin Athari,Maha Moh'd Wahbi Atout,Leticia Avila-Burgos,Ahmed Awaisu,Sina Azadnajafabad,BB Darshan,Hassan Babamohamadi,Muhammad Badar,Alaa Badawi,Ashish D Badiye,Nayereh Baghcheghi,Nasser Bagheri,Sara Bagherieh,Sulaiman Bah,Saeed Bahadory,Ruhai Bai,Atif Amin Baig,Ovidiu Constantin Baltatu,Hamid Reza Baradaran,Martina Barchitta,Mainak Bardhan,Noel C Barengo,Till Winfried Bärnighausen,Mark Thomaz Ugliara Barone,Francesco Barone-Adesi,Amadou Barrow,Hamideh Bashiri,Afisu Basiru,Sanjay Basu,Saurav Basu,Abdul-Monim Mohammad Batiha,Kavita Batra,Mulat Tirfie Bayih,Nebiyou Simegnew Bayileyegn,Amir Hossein Behnoush,Alehegn Bekele Bekele,Melaku Ashagrie Belete,Uzma Iqbal Belgaumi,Luis Belo,Derrick A Bennett,Isabela M Bensenor,Kidanemaryam Berhe,Alemshet Yirga Berhie,Sonu Bhaskar,Ajay Nagesh Bhat,Jasvinder Singh Bhatti,Boris Bikbov,Faiq Bilal,Bagas Suryo Bintoro,Saeid Bitaraf,Veera R Bitra,Vesna Bjegovic-Mikanovic,Virginia Bodolica,Archith Boloor,Michael Brauer

Journal

The Lancet

Published Date

2023/7/15

BackgroundDiabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050.MethodsEstimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and …

The burden of disease, injuries, and risk factors in Mexico: 1990-2021 update

Authors

Rafael Lozano,Christian Razo,Alejandra Montoya,Linda Morales-Juarez,María J Ríos-Blancas,Jack Cagney

Journal

Gaceta médica de México

Published Date

2023/12

LOZANO, Rafael et al. The burden of disease, injuries, and risk factors in Mexico: 1990-2021 update. Gac. Méd. Méx [online]. 2023, vol. 159, n. 6, pp. 469-478. Epub 26-Mar-2024. ISSN 2696-1288. https://doi. org/10.24875/gmm. 23000428.Background:For thirty years, Mexico has studied the burden of disease in order to inform health decisions.Objective:To analyze the burden of disease, injuries, and risk factors in Mexico between 1990 and 2021.Material and methods:Estimates from the Global Burden of Disease 2021 study were used to analyze mortality, years of life lost due to premature mortality, years lived with disability and disability-adjusted life years, as well as the burden attributable to risk factors by sex, age and state of the country.Results:Infant mortality decreased by 39.4% from 1990 to 2000 and by 49.0% from 2000 to 2019. At the national level, mortality decreased by 27.5% between 1990 and 2019, but increased in 2020 and 2021 across all states, especially in adults aged from 35 to 64 years due to the COVID-19 pandemic, which contributed with 24.3% of deaths in 2019. Significant differences in mortality were observed according to age and sex. The burden attributable to metabolic risk factors did increase, while alcohol and tobacco consumption decreased. Access to drinking water and sanitation showed improvements.Conclusions:Assessing the burden of disease is crucial in order to design effective strategies to address current health needs and future healthcare challenges.

La carga de la enfermedad, lesiones y factores de riesgo en México. Actualización del período 1990-2021

Authors

Rafael Lozano,Christian Razo,Alejandra Montoya,Linda Morales-Juárez,María J Ríos-Blancas,Jack Cagney

Journal

Gaceta médica de México

Published Date

2023

Antecedentes Desde hace treinta años, México ha estudiado la carga de la enfermedad para sustentar decisiones en salud. Objetivo Analizar la carga de enfermedad, lesiones y factores de riesgo en México entre 1990 y 2021. Material y métodos Se utilizaron las estimaciones del Global Burden of Disease 2021 para analizar la mortalidad, los años de vida perdidos por muerte prematura, los años vividos con discapacidad y los años de vida saludable perdidos, así como la carga atribuible a los factores de riesgos por sexo, edad y entidad federativa. Resultados La mortalidad infantil disminuyó 39.4% de 1990 a 2000, y 49.0% de 2000 a 2019. En el ámbito nacional, la mortalidad decreció 27.5% entre 1990 y 2019, pero ascendió en 2020 y 2021 en todos los estados, especialmente en adultos de 35 a 64 años, debido a la pandemia de COVID-19, que contribuyó con 24.3% de las defunciones en 2019. Se observaron diferencias significativas en la mortalidad según la edad y el sexo. La carga atribuible a los factores de riesgo metabólicos se incrementó, mientras que la atribuible el consumo de alcohol y tabaco disminuyó. El acceso al agua potable y saneamiento mejoró. Conclusiones Evaluar la carga de enfermedad es crucial para diseñar estrategias eficaces para abordar las necesidades actuales y los futuros desafíos en salud.

Estimating mortality and disability in Peru before the COVID-19 pandemic: a systematic analysis from the Global Burden of the Disease Study 2019

Authors

Maria Jesus Rios-Blancas,Victoria Pando-Robles,Christian Razo,Cesar P Carcamo,Walter Mendoza,Kevin Pacheco-Barrios,J Jaime Miranda,Van Charles Lansingh,Takele Gezahegn Demie,Manika Saha,Osaretin Christabel Okonji,Arzu Yigit,Lucero Cahuana-Hurtado,Pamela R Chacón-Uscamaita,Eduardo Bernabe,Carlos Culquichicon,Jesus Lorenzo Chirinos-Caceres,Rosario Cárdenas,Jacqueline Elizabeth Alcalde-Rabanal,Francisco J Barrera,Beatriz Paulina Ayala Quintanilla,Seyed Afshin Shorofi,Nuwan Darshana Wickramasinghe,Nuno Ferreira,Louay Almidani,Vivek Kumar Gupta,Hanie Karimi,Daniel Shewaye Alayu,Catherine P Benziger,Takeshi Fukumoto,Ebrahim Mostafavi,Elrashdy Moustafa Mohamed Redwan,Mesfin Gebrehiwot,Khaled Khatab,Ai Koyanagi,Fiorella Krapp,Seung Lee,Maryam Noori,Ibrahim Qattea,Victor Daniel Rosenthal,Joseph W Sakshaug,Birhanu Wagaye,Iman Zare,Doris V Ortega-Altamirano,Efrén Murillo-Zamora,Dominique Vervoort,Diego Augusto Santos Silva,Abderrahim Oulhaj,Brenda Yuliana Herrera-Serna,Rahul Mehra,Mehrdad Amir-Behghadami,Nasrin Adib,Sandra Cortés,Anh Kim Dang,Binh Thanh Nguyen,Ali H Mokdad,Simon I Hay,Christopher JL Murray,Rafael Lozano,Patricia J García

Journal

Frontiers in public health

Published Date

2023/6/22

Background Estimating and analyzing trends and patterns of health loss are essential to promote efficient resource allocation and improve Peru’s healthcare system performance. Methods Using estimates from the Global Burden of Disease (GBD), Injuries, and Risk Factors Study (2019), we assessed mortality and disability in Peru from 1990 to 2019. We report demographic and epidemiologic trends in terms of population, life expectancy at birth (LE), mortality, incidence, prevalence, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) caused by the major diseases and risk factors in Peru. Finally, we compared Peru with 16 countries in the Latin American (LA) region. Results The Peruvian population reached 33.9 million inhabitants (49.9% women) in 2019. From 1990 to 2019, LE at birth increased from 69.2 (95% uncertainty interval 67.8–70.3) to 80.3 (77.2–83.2) years. This increase was driven by the decline in under-5 mortality (−80.7%) and mortality from infectious diseases in older age groups (+60 years old). The number of DALYs in 1990 was 9.2 million (8.5–10.1) and reached 7.5 million (6.1–9.0) in 2019. The proportion of DALYs due to non-communicable diseases (NCDs) increased from 38.2% in 1990 to 67.9% in 2019. The all-ages and age-standardized DALYs rates and YLLs rates decreased, but YLDs rates remained constant. In 2019, the leading causes of DALYs were neonatal disorders, lower respiratory infections (LRIs), ischemic heart disease, road injuries, and low back pain. The leading risk factors associated with DALYs in 2019 were undernutrition, high body mass index …

La carga de la enfermedad en México de 1990 a 2021

Authors

German Fajardo-Dolci,Roberto Tapia-Conyer,Rafael Lozano

Journal

Gaceta médica de México

Published Date

2023/12

AntecedentesEl estudio Global Burden of Disease (GBD) comenzó hace 30 años con el objetivo de proporcionar evaluaciones oportunas, válidas y relevantes de condiciones de salud en el mundo. La pregunta que se buscaba responder hace tres décadas era¿ cuáles son las principales causas de muerte en el mundo? Además de llenar un hueco en la información sobre la salud mundial, se buscaba ordenar las prioridades de salud para mejorar la asignación de recursos y hacer más eficiente el uso del dinero invertido en salud. El primer reporte GBD se inició en 1991 y la publicación de los primeros resultados se llevó a cabo entre 1993 y 1997, 1-3 los cuales documentaron las estimaciones de la carga de la enfermedad en ocho regiones, 106 condiciones y 10 factores de riesgo, divididos en cinco grupos de edad para 1990.

Impacto de COVID-19 en la esperanza de vida en México. Un análisis basado en el estudio Global Burden of Disease

Authors

Rafael Lozano,Alejandra Montoya,Christian Razo,Austin Schumacher,Haley Confort,Spencer Pease,Darwin Jones,Stefanie Watson,Mohsen Naghavi

Journal

Gac Med Mex

Published Date

2023

Antecedentes Entre 2020 y 2021, México experimentó 2.21 millones de defunciones, de las cuales 25.3% estuvo relacionado con infección por SARS-COV-2. Objetivos Evaluar la mortalidad por COVID-19 en 2020-2021, determinar su influencia en la esperanza de vida al nacer a nivel nacional, estatal y en países seleccionados de la región, así como analizarla en función del perfil sociodemográfico. Material y métodos Se utilizaron datos del Global Burden of Disease 2021 para reportar la mortalidad, el impacto en la esperanza de vida y las causas subyacentes entre 2019 y 2021. Se usó una regresión cuadrática para evaluar la mortalidad en exceso como indicador de la respuesta de los estados a la pandemia, considerando su estructura sociodemográfica. Resultados Entre 2020 y 2021, se registraron 708 971 muertes en exceso, que disminuyeron la esperanza de vida al nacer en 4.6 años; 76% de esta reducción se atribuyó a COVID-19. La tasa de mortalidad por COVID-19 fue superior a la esperada conforme a las condiciones sociodemográficas de las entidades. Conclusiones En México y los países de la región, la pandemia fue devastadora y generó regresiones en la esperanza de vida al nacer, que variaron de dos a nueve años. Se requiere más investigación para entender las variaciones en sus efectos.

Catastrophic health expenditure during the COVID-19 pandemic in five countries: a time-series analysis

Authors

Annie Haakenstad,Corinne Bintz,Megan Knight,Kelly Bienhoff,Horacio Chacon-Torrico,Walter H Curioso,Joseph L Dieleman,Anna Gage,Emmanuela Gakidou,Simon I Hay,Nathaniel J Henry,Akram Hernández-Vásquez,Judith S Méndez Méndez,Héctor J Villarreal,Rafael Lozano

Journal

The Lancet Global Health

Published Date

2023/10/1

BackgroundThe COVID-19 pandemic disrupted health systems in 2020, but it is unclear how financial hardship due to out-of-pocket (OOP) health-care costs was affected. We analysed catastrophic health expenditure (CHE) in 2020 in five countries with available household expenditure data: Belarus, Mexico, Peru, Russia, and Viet Nam. In Mexico and Peru, we also conducted an analysis of drivers of change in CHE in 2020 using publicly available data.MethodsIn this time-series analysis, we defined CHE as when OOP health-care spending exceeds 10% of consumption expenditure. Data for 2004–20 were obtained from individual and household level survey microdata (available for Mexico and Peru only), and tabulated data from the National Statistical Committee of Belarus and the World Bank Health Equity and Financial Protection Indicator database (for Viet Nam and Russia). We compared 2020 CHE with the …

Evaluation of effective coverage for type 2 diabetes in Mexican primary care health information systems: a retrospective registry analysis

Authors

Héctor Gallardo-Rincón,María Jesús Ríos-Blancas,Alejandra Montoya,Rodrigo Saucedo-Martínez,Linda Morales-Juárez,Ricardo Mujica,Alejandra Cantoral,Lorena Suarez Idueta,Rafael Lozano,Roberto Tapia-Conyer

Journal

International Journal for Equity in Health

Published Date

2023/4/5

BackgroundAs the leading cause of disability and the fourth leading cause of premature death in Mexico, type 2 diabetes (T2D) represents a serious public health concern. The incidence of diabetes has increased dramatically in recent years, and data from the Mexican National Health and Nutrition Survey (ENSANUT) indicate that many people remain undiagnosed. Persistent socioeconomic health care barriers exacerbate this situation, as T2D morbidity and mortality are worsened in vulnerable populations, such as those without social security. We evaluated the performance of public primary health centers (PHCs) in T2D medical attention through the measure of effective coverage (EC, a combined measure of health care need, use, and quality) at national, state, health jurisdiction, and municipality levels.MethodsThis retrospective analysis used blinded data recorded during 2017 in the Non-communicable …

Equity in out-of-pocket health expenditure: Evidence from a health insurance program reform in Mexico

Authors

Rocío Garcia-Diaz,Sandra G Sosa-Rubí,Rafael Lozano,Edson Serván-Mori

Journal

Journal of Global Health

Published Date

2023

BackgroundThe fragmentation of health systems in low-and middle-income countries (LMICs) deepens health inequities and shifts the economic burden of health care to families via out-of-pocket spending (OOPHE). This problem has been addressed by introducing public health insurance programs for poor people; however, there is a lack of knowledge about how equitable these programs are. We aimed to analyse the long-term effects of the Seguro Popular (SP) voluntary health insurance program, recently phased out and replaced by the Health Institute for Welfare (Instituto de Salud para el Bienestar (INSABI)), on OOPHE equity in the poor Mexican population.MethodsWe conducted a pooled cross-sectional analysis using eleven waves of the National Household Income and Expenditure Survey (2002-2020). We identified the effect of SP by selecting households without social security (with SP or without health …

Inequitable Financial Protection in Health for Indigenous Populations: the Mexican Case

Authors

Edson Serván-Mori,Sergio Meneses-Navarro,Rocio Garcia-Diaz,Laura Flamand,Octavio Gómez-Dantés,Rafael Lozano

Journal

Journal of Racial and Ethnic Health Disparities

Published Date

2023/9/11

BackgroundThere is an important gap in the literature concerning the level, inequality, and evolution of financial protection for indigenous (IH) and non-indigenous (NIH) households in low- and middle-income countries. This paper offers an assessment of the level, socioeconomic inequality and middle-term trends of catastrophic (CHE), impoverishing (IHE), and excessive (EHE) health expenditures in Mexican IHs and NIHs during the period 2008–2020.MethodsWe conducted a pooled cross-sectional analysis using the last seven waves of the National Household Income and Expenditure Survey (n = 315,829 households). We assessed socioeconomic inequality in CHE, IHE, and EHE by estimating their Wagstaff concentration indices according to indigenous status. We adjusted the CHE, IHE, and EHE by estimating a maximum-likelihood two-stage probit model with robust standard errors.ResultsWe observed that …

Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis

Authors

Caroline Stein,Hasan Nassereldine,Reed JD Sorensen,Joanne O Amlag,Catherine Bisignano,Sam Byrne,Emma Castro,Kaleb Coberly,James K Collins,Jeremy Dalos,Farah Daoud,Amanda Deen,Emmanuela Gakidou,John R Giles,Erin N Hulland,Bethany M Huntley,Kasey E Kinzel,Rafael Lozano,Ali H Mokdad,Tom Pham,David M Pigott,Robert C Reiner Jr,Theo Vos,Simon I Hay,Christopher JL Murray,Stephen S Lim

Published Date

2023/3/11

BackgroundUnderstanding the level and characteristics of protection from past SARS-CoV-2 infection against subsequent re-infection, symptomatic COVID-19 disease, and severe disease is essential for predicting future potential disease burden, for designing policies that restrict travel or access to venues where there is a high risk of transmission, and for informing choices about when to receive vaccine doses. We aimed to systematically synthesise studies to estimate protection from past infection by variant, and where data allow, by time since infection.MethodsIn this systematic review and meta-analysis, we identified, reviewed, and extracted from the scientific literature retrospective and prospective cohort studies and test-negative case-control studies published from inception up to Sept 31, 2022, that estimated the reduction in risk of COVID-19 among individuals with a past SARS-CoV-2 infection in comparison …

Quantifying Disparities in the Continuum of Care for Maternal Health Attributable to Age Discrimination in Mexico, 1994–2018

Authors

Ileana Heredia-Pi,Edson Serván-Mori,Nancy Armenta-Paulino,Gustavo Nigenda,Hortensia Reyes-Morales,Rafael Lozano

Journal

Sexuality Research and Social Policy

Published Date

2023/9

IntroductionIt has been widely recognized that adolescents exhibit a low coverage rate for continuous maternal health services as a result of structural social disadvantages, often exacerbated by age-related discrimination. Notwithstanding its importance, this fact has received little attention during quantitative evaluations of health system performance. The present study quantified the magnitude and trend of the adult-adolescent gap in continuum of care (CoC) coverage for maternal health over the last quarter century. A decomposition analysis of the gap was performed to ascertain the portion of disparities attributable to age discrimination.MethodsA pooled, cross-sectional, and retrospective study was conducted utilizing data from the 1997, 2009, 2014, and 2018 waves of the population-based National Survey of Demographic Dynamics in Mexico. After describing the sociodemographic characteristics and CoC …

Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026

Authors

Angela E Micah,Kayleigh Bhangdia,Ian E Cogswell,Dylan Lasher,Brendan Lidral-Porter,Emilie R Maddison,Trang Nhu Ngoc Nguyen,Nishali Patel,Paola Pedroza,Juan Solorio,Hayley Stutzman,Golsum Tsakalos,Yifeng Wang,Wesley Warriner,Yingxi Zhao,Bianca S Zlavog,Cristiana Abbafati,Jaffar Abbas,Mohsen Abbasi-Kangevari,Zeinab Abbasi-Kangevari,Michael Abdelmasseh,Deldar Morad Abdulah,Aidin Abedi,Kedir Hussein Abegaz,ES Abhilash,Richard Gyan Aboagye,Hassan Abolhassani,Michael RM Abrigo,Hiwa Abubaker Ali,Eman Abu-Gharbieh,Mohammed Hussien Adem,Muhammad Sohail Afzal,Ali Ahmadi,Haroon Ahmed,Tarik Ahmed Rashid,Budi Aji,Hossein Akbarialiabad,Yibeltal Akelew,Hanadi Al Hamad,Khurshid Alam,Fahad Mashhour Alanezi,Turki M Alanzi,Mohammed Khaled Al-Hanawi,Robert Kaba Alhassan,Syed Mohamed Aljunid,Sami Almustanyir,Rajaa M Al-Raddadi,Nelson Alvis-Guzman,Nelson J Alvis-Zakzuk,Azmeraw T Amare,Edward Kwabena Ameyaw,Mostafa Amini-Rarani,Hubert Amu,Robert Ancuceanu,Tudorel Andrei,Sumadi Lukman Anwar,Francis Appiah,Muhammad Aqeel,Jalal Arabloo,Morteza Arab-Zozani,Aleksandr Y Aravkin,Olatunde Aremu,Raphael Taiwo Aruleba,Seyyed Shamsadin Athari,Leticia Avila-Burgos,Martin Amogre Ayanore,Samad Azari,Atif Amin Baig,Abere Tilahun Bantie,Amadou Barrow,Pritish Baskaran,Sanjay Basu,Abdul-Monim Mohammad Batiha,Bernhard T Baune,Zombor Berezvai,Nikha Bhardwaj,Pankaj Bhardwaj,Sonu Bhaskar,Micheal Kofi Boachie,Virginia Bodolica,João Silva Botelho Botelho,Dejana Braithwaite,Nicholas JK Breitborde,Reinhard Busse,Lucero Cahuana-Hurtado,Ferrán Catalá-López,Collins Chansa,Jaykaran Charan,Vijay Kumar Chattu,Simiao Chen,Isaac Sunday Chukwu,Omid Dadras,Lalit Dandona,Rakhi Dandona,Abdollah Dargahi,Sisay Abebe Debela,Edgar Denova-Gutiérrez,Belay Desye,Samath Dhamminda Dharmaratne,Nancy Diao,Linh Phuong Doan,Milad Dodangeh,Wendel Mombaque dos Santos,Leila Doshmangir,John Dube,Ebrahim Eini,Maysaa El Sayed Zaki,Maha El Tantawi,Daniel Berhanie Enyew,Sharareh Eskandarieh,Mohamad Ezati Asar,Adeniyi Francis Fagbamigbe,Jose A Faraon,Ali Fatehizadeh,Hamed Fattahi,Ginenus Fekadu,Florian Fischer,Nataliya A Foigt,Kayode Raphael Fowobaje,Alberto Freitas,Takeshi Fukumoto,Nancy Fullman,Peter Andras Gaal,Amiran Gamkrelidze,MA Garcia-Gordillo,Mesfin Gebrehiwot,Urge Gerema,Mansour Ghafourifard,Seyyed-Hadi Ghamari,Reza Ghanbari,Ahmad Ghashghaee,Ali Gholamrezanezhad,Mahaveer Golechha,Davide Golinelli,Yitayal Ayalew Goshu,Girma Garedew Goyomsa,Avirup Guha,Damitha Asanga Gunawardane,Bhawna Gupta,Samer Hamidi,Harapan Harapan,Reza Hashempour,Khezar Hayat,Golnaz Heidari,Ileana Heredia-Pi,Claudiu Herteliu,Demisu Zenbaba Heyi,Kamal Hezam,Yuta Hiraike,Mbuzeleni Mbuzeleni Hlongwa

Journal

The Lancet Global Health

Published Date

2023/3/1

Background The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic; characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic; and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending …

Intergenerational replication of teenage pregnancy and educational attainment in Mexico

Authors

Edson Serván-Mori,Amado D Quezada-Sánchez,Sandra G Sosa-Rubí,Ileana Heredia-Pi,Rafael Lozano

Journal

Archives of Sexual Behavior

Published Date

2022/11

Mexico ranks among the OECD countries with the highest prevalence of teenage pregnancies, exhibiting a fertility rate of 70.6 births for every 1000 adolescents. Mexican adolescents with a history of pregnancy are twice as likely to lag behind in their studies as those who have not been pregnant. Research on adolescent maternity and its explanatory mechanisms is required as a basis for implementing policies and programs that effectively curb teenage pregnancy-related behaviors, prevent educational gaps, and reduce the intergenerational transmission of poverty. Based on quasi-experimental methodology and a non-recursive structural equation model with instrumental variables, this paper analyzed the intergenerational transmission of teenage pregnancy from mothers to daughters, as well as the relationship between teenage pregnancy and educational attainment. Using data from the 2009 National Survey of …

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis

Authors

Ryan M Barber,Reed JD Sorensen,David M Pigott,Catherine Bisignano,Austin Carter,Joanne O Amlag,James K Collins,Cristiana Abbafati,Christopher Adolph,Adrien Allorant,Aleksandr Y Aravkin,Bree L Bang-Jensen,Emma Castro,Suman Chakrabarti,Rebecca M Cogen,Emily Combs,Haley Comfort,Kimberly Cooperrider,Xiaochen Dai,Farah Daoud,Amanda Deen,Lucas Earl,Megan Erickson,Samuel B Ewald,Alize J Ferrari,Abraham D Flaxman,Joseph Jon Frostad,Nancy Fullman,John R Giles,Gaorui Guo,Jiawei He,Monika Helak,Erin N Hulland,Bethany M Huntley,Alice Lazzar-Atwood,Kate E LeGrand,Stephen S Lim,Akiaja Lindstrom,Emily Linebarger,Rafael Lozano,Beatrice Magistro,Deborah Carvalho Malta,Johan Månsson,Ana M Mantilla Herrera,Ali H Mokdad,Lorenzo Monasta,Mohsen Naghavi,Shuhei Nomura,Christopher M Odell,Latera Tesfaye Olana,Samuel M Ostroff,Maja Pasovic,Spencer A Pease,Robert C Reiner Jr,Grace Reinke,Antonio Luiz P Ribeiro,Damian F Santomauro,Aleksei Sholokhov,Emma E Spurlock,Ruri Syailendrawati,Roman Topor-Madry,Anh Truc Vo,Theo Vos,Rebecca Walcott,Ally Walker,Kirsten E Wiens,Charles Shey Wiysonge,Nahom Alemseged Worku,Peng Zheng,Simon I Hay,Emmanuela Gakidou,Christopher JL Murray

Journal

The Lancet

Published Date

2022/6/25

BackgroundTimely, accurate, and comprehensive estimates of SARS-CoV-2 daily infection rates, cumulative infections, the proportion of the population that has been infected at least once, and the effective reproductive number (Reffective) are essential for understanding the determinants of past infection, current transmission patterns, and a population's susceptibility to future infection with the same variant. Although several studies have estimated cumulative SARS-CoV-2 infections in select locations at specific points in time, all of these analyses have relied on biased data inputs that were not adequately corrected for. In this study, we aimed to provide a novel approach to estimating past SARS-CoV-2 daily infections, cumulative infections, and the proportion of the population infected, for 190 countries and territories from the start of the pandemic to Nov 14, 2021. This approach combines data from reported cases …

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1 …

Authors

Thomas J Bollyky,Erin N Hulland,Ryan M Barber,James K Collins,Samantha Kiernan,Mark Moses,David M Pigott,Robert C Reiner Jr,Reed JD Sorensen,Cristiana Abbafati,Christopher Adolph,Adrien Allorant,Joanne O Amlag,Aleksandr Y Aravkin,Bree Bang-Jensen,Austin Carter,Rachel Castellano,Emma Castro,Suman Chakrabarti,Emily Combs,Xiaochen Dai,William James Dangel,Carolyn Dapper,Amanda Deen,Bruce B Duncan,Lucas Earl,Megan Erickson,Samuel B Ewald,Tatiana Fedosseeva,Alize J Ferrari,Abraham D Flaxman,Nancy Fullman,Emmanuela Gakidou,Bayan Galal,John Gallagher,John R Giles,Gaorui Guo,Jiawei He,Monika Helak,Bethany M Huntley,Bulat Idrisov,Casey Johanns,Kate E LeGrand,Ian D Letourneau,Akiaja Lindstrom,Emily Linebarger,Paulo A Lotufo,Rafael Lozano,Beatrice Magistro,Deborah Carvalho Malta,Johan Månsson,Ana M Mantilla Herrera,Fatima Marinho,Alemnesh H Mirkuzie,Ali H Mokdad,Lorenzo Monasta,Paulami Naik,Shuhei Nomura,James Kevin O'Halloran,Christopher M Odell,Latera Tesfaye Olana,Samuel M Ostroff,Maja Pasovic,Valeria Maria de Azeredo Passos,Louise Penberthy,Grace Reinke,Damian Francesco Santomauro,Maria Inês Schmidt,Aleksei Sholokhov,Emma Spurlock,Christopher E Troeger,Elena Varavikova,Anh T Vo,Theo Vos,Rebecca Walcott,Ally Walker,Simon D Wigley,Charles Shey Wiysonge,Nahom Alemseged Worku,Yifan Wu,Sarah Wulf Hanson,Peng Zheng,Simon I Hay,Christopher JL Murray,Joseph L Dieleman

Journal

The Lancet

Published Date

2022/4/16

BackgroundNational rates of COVID-19 infection and fatality have varied dramatically since the onset of the pandemic. Understanding the conditions associated with this cross-country variation is essential to guiding investment in more effective preparedness and response for future pandemics.MethodsDaily SARS-CoV-2 infections and COVID-19 deaths for 177 countries and territories and 181 subnational locations were extracted from the Institute for Health Metrics and Evaluation's modelling database. Cumulative infection rate and infection-fatality ratio (IFR) were estimated and standardised for environmental, demographic, biological, and economic factors. For infections, we included factors associated with environmental seasonality (measured as the relative risk of pneumonia), population density, gross domestic product (GDP) per capita, proportion of the population living below 100 m, and a proxy for previous …

Quantifying the effects of the COVID-19 pandemic on gender equality on health, social, and economic indicators: a comprehensive review of data from March, 2020, to September, 2021

Authors

Luisa S Flor,Joseph Friedman,Cory N Spencer,John Cagney,Alejandra Arrieta,Molly E Herbert,Caroline Stein,Erin C Mullany,Julia Hon,Vedavati Patwardhan,Ryan M Barber,James K Collins,Simon I Hay,Stephen S Lim,Rafael Lozano,Ali H Mokdad,Christopher JL Murray,Robert C Reiner,Reed JD Sorensen,Annie Haakenstad,David M Pigott,Emmanuela Gakidou

Published Date

2022/6/25

BackgroundGender is emerging as a significant factor in the social, economic, and health effects of COVID-19. However, most existing studies have focused on its direct impact on health. Here, we aimed to explore the indirect effects of COVID-19 on gender disparities globally.MethodsWe reviewed publicly available datasets with information on indicators related to vaccine hesitancy and uptake, health care services, economic and work-related concerns, education, and safety at home and in the community. We used mixed effects regression, Gaussian process regression, and bootstrapping to synthesise all data sources. We accounted for uncertainty in the underlying data and modelling process. We then used mixed effects logistic regression to explore gender gaps globally and by region.FindingsBetween March, 2020, and September, 2021, women were more likely to report employment loss (26·0% [95 …

Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019

Authors

Jorge R Ledesma,Jianing Ma,Avina Vongpradith,Emilie R Maddison,Amanda Novotney,Molly H Biehl,Kate E LeGrand,Jennifer M Ross,Deepa Jahagirdar,Dana Bryazka,Rachel Feldman,Hassan Abolhassani,Akine Eshete Abosetugn,Eman Abu-Gharbieh,Oladimeji M Adebayo,Qorinah Estiningtyas Sakilah Adnani,Saira Afzal,Bright Opoku Ahinkorah,Sajjad Ahmad Ahmad,Sepideh Ahmadi,Tarik Ahmed Rashid,Yusra Ahmed Salih,Addis Aklilu,Chisom Joyqueenet Akunna,Hanadi Al Hamad,Fares Alahdab,Yosef Alemayehu,Kefyalew Addis Alene,Beriwan Abdulqadir Ali,Liaqat Ali,Vahid Alipour,Hesam Alizade,Rajaa M Al-Raddadi,Nelson Alvis-Guzman,Saeed Amini,Arianna Maever L Amit,Jason A Anderson,Sofia Androudi,Carl Abelardo T Antonio,Catherine M Antony,Razique Anwer,Jalal Arabloo,Asrat Arja,Mulusew A Asemahagn,Sachin R Atre,Gulrez Shah Azhar,BB Darshan,Atif Amin Baig,Maciej Banach,Hiba Jawdat Barqawi,Fabio Barra,Amadou Barrow,Sanjay Basu,Uzma Iqbal Belgaumi,Akshaya Srikanth Bhagavathula,Nikha Bhardwaj,Pankaj Bhardwaj,Natalia V Bhattacharjee,Krittika Bhattacharyya,Ali Bijani,Boris Bikbov,Archith Boloor,Nikolay Ivanovich Briko,Danilo Buonsenso,Sharath Burugina Nagaraja,Zahid A Butt,Austin Carter,Felix Carvalho,Jaykaran Charan,Souranshu Chatterjee,Soosanna Kumary Chattu,Vijay Kumar Chattu,Devasahayam J Christopher,Dinh-Toi Chu,Mareli M Claassens,Omid Dadras,Amare Belachew Dagnew,Xiaochen Dai,Lalit Dandona,Rakhi Dandona,Parnaz Daneshpajouhnejad,Aso Mohammad Darwesh,Deepak Dhamnetiya,Mostafa Dianatinasab,Daniel Diaz,Linh Phuong Doan,Sahar Eftekharzadeh,Muhammed Elhadi,Amir Emami,Shymaa Enany,Jose A Faraon,Farshad Farzadfar,Eduarda Fernandes,Lorenzo Ferro Desideri,Irina Filip,Florian Fischer,Masoud Foroutan,Tahvi D Frank,Alberto L Garcia-Basteiro,Christian Garcia-Calavaro,Tushar Garg,Biniyam Sahiledengle Geberemariyam,Keyghobad Ghadiri,Ahmad Ghashghaee,Mahaveer Golechha,Amador Goodridge,Bhawna Gupta,Sapna Gupta,Veer Bala Gupta,Vivek Kumar Gupta,Mohammad Rifat Haider,Samer Hamidi,Asif Hanif,Shafiul Haque,Harapan Harapan,Arief Hargono,Ahmed I Hasaballah,Abdiwahab Hashi,Shoaib Hassan,Hadi Hassankhani,Khezar Hayat,Kamal Hezam,Ramesh Holla,Mehdi Hosseinzadeh,Mihaela Hostiuc,Mowafa Househ,Rabia Hussain,Segun Emmanuel Ibitoye,Irena M Ilic,Milena D Ilic,Seyed Sina Naghibi Irvani,Nahlah Elkudssiah Ismail,Ramaiah Itumalla,Jalil Jaafari,Kathryn H Jacobsen,Vardhmaan Jain,Fatemeh Javanmardi,Sathish Kumar Jayapal,Shubha Jayaram,Ravi Prakash Jha,Jost B Jonas,Nitin Joseph,Farahnaz Joukar,Zubair Kabir,Ashwin Kamath,Tanuj Kanchan,Himal Kandel,Patrick DMC Katoto,Gbenga A Kayode,Parkes J Kendrick

Journal

The lancet infectious diseases

Published Date

2022/2/1

BackgroundTuberculosis is a major contributor to the global burden of disease, causing more than a million deaths annually. Given an emphasis on equity in access to diagnosis and treatment of tuberculosis in global health targets, evaluations of differences in tuberculosis burden by sex are crucial. We aimed to assess the levels and trends of the global burden of tuberculosis, with an emphasis on investigating differences in sex by HIV status for 204 countries and territories from 1990 to 2019.MethodsWe used a Bayesian hierarchical Cause of Death Ensemble model (CODEm) platform to analyse 21 505 site-years of vital registration data, 705 site-years of verbal autopsy data, 825 site-years of sample-based vital registration data, and 680 site-years of mortality surveillance data to estimate mortality due to tuberculosis among HIV-negative individuals. We used a population attributable fraction approach to estimate …

Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021

Authors

Sarah Wulf Hanson,Cristiana Abbafati,Joachim G Aerts,Ziyad Al-Aly,Charlie Ashbaugh,Tala Ballouz,Oleg Blyuss,Polina Bobkova,Gouke Bonsel,Svetlana Borzakova,Danilo Buonsenso,Denis Butnaru,Austin Carter,Helen Chu,Cristina De Rose,Mohamed Mustafa Diab,Emil Ekbom,Maha El Tantawi,Victor Fomin,Robert Frithiof,Aysylu Gamirova,Petr V Glybochko,Juanita A Haagsma,Shaghayegh Haghjooy Javanmard,Erin B Hamilton,Gabrielle Harris,Majanka H Heijenbrok-Kal,Raimund Helbok,Merel E Hellemons,David Hillus,Susanne M Huijts,Michael Hultström,Waasila Jassat,Florian Kurth,Marie Larsson,Miklós Lipcsey,Chelsea Liu,Callan D Loflin,Andrei Malinovschi,Wenhui Mao,Lyudmila Mazankova,Denise McCulloch,Dominik Menges,Noushin Mohammadifard,Daniel Munblit,Nikita A Nekliudov,Osondu Ogbuoji,Ismail M Osmanov,José L Peñalvo,Maria Skaalum Petersen,Milo A Puhan,Mujibur Rahman,Verena Rass,Nickolas Reinig,Gerard M Ribbers,Antonia Ricchiuto,Sten Rubertsson,Elmira Samitova,Nizal Sarrafzadegan,Anastasia Shikhaleva,Kyle E Simpson,Dario Sinatti,Joan B Soriano,Ekaterina Spiridonova,Fridolin Steinbeis,Andrey A Svistunov,Piero Valentini,Brittney J Van De Water,Rita Van den Berg-Emons,Ewa Wallin,Martin Witzenrath,Yifan Wu,Hanzhang Xu,Thomas Zoller,Christopher Adolph,James Albright,Joanne O Amlag,Aleksandr Y Aravkin,Bree L Bang-Jensen,Catherine Bisignano,Rachel Castellano,Emma Castro,Suman Chakrabarti,James K Collins,Xiaochen Dai,Farah Daoud,Carolyn Dapper,Amanda Deen,Bruce B Duncan,Megan Erickson,Samuel B Ewald,Alize J Ferrari,Abraham D Flaxman,Nancy Fullman,Amiran Gamkrelidze,John R Giles,Gaorui Guo,Simon I Hay,Jiawei He,Monika Helak,Erin N Hulland,Maia Kereselidze,Kris J Krohn,Alice Lazzar-Atwood,Akiaja Lindstrom,Rafael Lozano,Deborah Carvalho Malta,Johan Månsson,Ana M Mantilla Herrera,Ali H Mokdad,Lorenzo Monasta,Shuhei Nomura,Maja Pasovic,David M Pigott,Robert C Reiner,Grace Reinke,Antonio Luiz P Ribeiro,Damian Francesco Santomauro,Aleksei Sholokhov,Emma Elizabeth Spurlock,Rebecca Walcott,Ally Walker,Charles Shey Wiysonge,Peng Zheng,Janet Prvu Bettger,Christopher JL Murray,Theo Vos,Global Burden of Disease Long COVID Collaborators

Journal

Jama

Published Date

2022/10/25

ImportanceSome individuals experience persistent symptoms after initial symptomatic SARS-CoV-2 infection (often referred to as Long COVID).ObjectiveTo estimate the proportion of males and females with COVID-19, younger or older than 20 years of age, who had Long COVID symptoms in 2020 and 2021 and their Long COVID symptom duration.Design, Setting, and ParticipantsBayesian meta-regression and pooling of 54 studies and 2 medical record databases with data for 1.2 million individuals (from 22 countries) who had symptomatic SARS-CoV-2 infection. Of the 54 studies, 44 were published and 10 were collaborating cohorts (conducted in Austria, the Faroe Islands, Germany, Iran, Italy, the Netherlands, Russia, Sweden, Switzerland, and the US). The participant data were derived from the 44 published studies (10 501 hospitalized individuals and 42 891 nonhospitalized individuals), the 10 …

Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic …

Authors

Annie Haakenstad,Caleb Mackay Salpeter Irvine,Megan Knight,Corinne Bintz,Aleksandr Y Aravkin,Peng Zheng,Vin Gupta,Michael RM Abrigo,Abdelrahman I Abushouk,Oladimeji M Adebayo,Gina Agarwal,Fares Alahdab,Ziyad Al-Aly,Khurshid Alam,Turki M Alanzi,Jacqueline Elizabeth Alcalde-Rabanal,Vahid Alipour,Nelson Alvis-Guzman,Arianna Maever L Amit,Catalina Liliana Andrei,Tudorel Andrei,Carl Abelardo T Antonio,Jalal Arabloo,Olatunde Aremu,Martin Amogre Ayanore,Maciej Banach,Till Winfried Bärnighausen,Celine M Barthelemy,Mohsen Bayati,Habib Benzian,Adam E Berman,Kelly Bienhoff,Ali Bijani,Boris Bikbov,Antonio Biondi,Archith Boloor,Reinhard Busse,Zahid A Butt,Luis Alberto Cámera,Ismael R Campos-Nonato,Rosario Cárdenas,Felix Carvalho,Collins Chansa,Soosanna Kumary Chattu,Vijay Kumar Chattu,Dinh-Toi Chu,Xiaochen Dai,Lalit Dandona,Rakhi Dandona,William James Dangel,Ahmad Daryani,Jan-Walter De Neve,Meghnath Dhimal,Isaac Oluwafemi Dipeolu,Shirin Djalalinia,Hoa Thi Do,Chirag P Doshi,Leila Doshmangir,Elham Ehsani-Chimeh,Maha El Tantawi,Eduarda Fernandes,Florian Fischer,Nataliya A Foigt,Artem Alekseevich Fomenkov,Masoud Foroutan,Takeshi Fukumoto,Nancy Fullman,Mohamed M Gad,Keyghobad Ghadiri,Mansour Ghafourifard,Ahmad Ghashghaee,Thomas Glucksman,Houman Goudarzi,Rajat Das Gupta,Randah R Hamadeh,Samer Hamidi,Josep Maria Haro,Edris Hasanpoor,Simon I Hay,Mohamed I Hegazy,Behzad Heibati,Nathaniel J Henry,Michael K Hole,Naznin Hossain,Mowafa Househ,Olayinka Stephen Ilesanmi,Mohammad-Hasan Imani-Nasab,Seyed Sina Naghibi Irvani,Sheikh Mohammed Shariful Islam,Mohammad Ali Jahani,Ankur Joshi,Rohollah Kalhor,Gbenga A Kayode,Nauman Khalid,Khaled Khatab,Adnan Kisa,Sonali Kochhar,Kewal Krishan,Barthelemy Kuate Defo,Dharmesh Kumar Lal,Faris Hasan Lami,Anders O Larsson,Janet L Leasher,Kate E LeGrand,Lee-Ling Lim,Narayan B Mahotra,Azeem Majeed,Afshin Maleki,Narayana Manjunatha,Benjamin Ballard Massenburg,Tomislav Mestrovic,GK Mini,Andreea Mirica,Erkin M Mirrakhimov,Yousef Mohammad,Shafiu Mohammed,Ali H Mokdad,Shane Douglas Morrison,Mohsen Naghavi,Duduzile Edith Ndwandwe,Ionut Negoi,Ruxandra Irina Negoi,Josephine W Ngunjiri,Cuong Tat Nguyen,Yeshambel T Nigatu,Obinna E Onwujekwe,Doris V Ortega-Altamirano,Nikita Otstavnov,Stanislav S Otstavnov,Mayowa O Owolabi,Abhijit P Pakhare,Veincent Christian Filipino Pepito,Norberto Perico,Hai Quang Pham,David M Pigott,Khem Narayan Pokhrel,Mohammad Rabiee,Navid Rabiee,Vafa Rahimi-Movaghar,David Laith Rawaf,Salman Rawaf,Lal Rawal,Giuseppe Remuzzi,Andre MN Renzaho,Serge Resnikoff,Nima Rezaei,Aziz Rezapour,Jennifer Rickard,Leonardo Roever,Maitreyi Sahu

Journal

The Lancet

Published Date

2022/6/4

BackgroundHuman resources for health (HRH) include a range of occupations that aim to promote or improve human health. The UN Sustainable Development Goals (SDGs) and the WHO Health Workforce 2030 strategy have drawn attention to the importance of HRH for achieving policy priorities such as universal health coverage (UHC). Although previous research has found substantial global disparities in HRH, the absence of comparable cross-national estimates of existing workforces has hindered efforts to quantify workforce requirements to meet health system goals. We aimed to use comparable and standardised data sources to estimate HRH densities globally, and to examine the relationship between a subset of HRH cadres and UHC effective coverage performance.MethodsThrough the International Labour Organization and Global Health Data Exchange databases, we identified 1404 country-years of …

Variation in the COVID-19 infection-fatality ratio by age, time, and geography during the pre-vaccine era: A systematic analysis

Authors

RJD Sorensen,RM Barber,DM Pigott,Austin Carter,CN Spencer,SM Ostroff,RC Reiner,Cristiana Abbafati,Christopher Adolph,Adrien Allorant,JO Amlag,Ay Aravkin,Sd Bachmeier,Bl Bang-Jensen,Catherine Bisignano,Ss Bloom,Rachel Castellano,Emma Castro,Jk Collins,Haley Comfort,Xc Dai,Wj Dangel,Carolyn Dapper,Amanda Deen,Lucas Earl,Megan Erickson,Sb Ewald,Aj Ferrari,Ad Flaxman,Jj Frostad,Nancy Fullman,Amiran Gamkrelidze,Jr Giles,Gr Guo,He Jw,Monika Helak,En Hulland,Bm Huntley,Maia Kereselidze,Alice Lazzar-Atwood,Ke Legrand,Akiaja Lindstrom,Emily Linebarger,Rafael Lozano,Beatrice Magistro,Dc Malta,Johan Mansson,Amm Herrera,Fatima Marinho,Ah Mirkuzie,Ah Mokdad,Lorenzo Monasta,Mohsen Naghavi,Hasan Nassereldine,Shuhei Nomura,Cm Odell,Lt Olana,Maja Pasovic,Sa Pease,Louise Penberthy,Grace Reinke,Alp Ribeiro,Df Santomauro,Aleksei Sholokhov,Natia Skhvitaridze,Ee Spurlock,Ruri Syailendrawati,Roman Topor-Madry,Vo At,Theo Vos,Rebecca Walcott,Ally Walker,Stefanie Watson,Cs Wiysonge,Na Worku,Peng Zheng,Si Hay,Emmanuela Gakidou,Cjl Murray

Journal

The Lancet

Published Date

2022

Background The infection-fatality ratio (IFR) is a metric that quantifies the likelihood of an individual dying once infected with a pathogen. Understanding the determinants of IFR variation for COVID-19, the disease caused by the SARS-CoV-2 virus, has direct implications for mitigation efforts with respect to clinical practice, non-pharmaceutical interventions, and the prioritisation of risk groups for targeted vaccine delivery. The IFR is also a crucial parameter in COVID-19 dynamic transmission models, providing a way to convert a population's mortality rate into an estimate of infections. Methods We estimated age-specific and all-age IFR by matching seroprevalence surveys to total COVID-19 mortality rates in a population. The term total COVID-19 mortality refers to an estimate of the total number of deaths directly attributable to COVID-19. After applying exclusion criteria to 5131 seroprevalence surveys, the IFR analyses were informed by 2073 all-age surveys and 718 age-specific surveys (3012 age-specific observations). When seroprevalence was reported by age group, we split total COVID-19 mortality into corresponding age groups using a Bayesian hierarchical model to characterise the non-linear age pattern of reported deaths for a given location. To remove the impact of vaccines on the estimated IFR age pattern, we excluded age-specific observations of seroprevalence and deaths that occurred after vaccines were introduced in a location. We estimated age-specific IFR with a non-linear meta-regression and used the resulting age pattern to standardise all-age IFR observations to the global age distribution. All IFR observations were adjusted …

Burden of diabetes and hyperglycaemia in adults in the Americas, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Authors

Ewerton Cousin,Maria Inês Schmidt,Kanyin Liane Ong,Rafael Lozano,Ashkan Afshin,Abdelrahman I Abushouk,Gina Agarwal,Marcela Agudelo-Botero,Ziyad Al-Aly,Jacqueline Elizabeth Alcalde-Rabanal,Nelson Alvis-Guzman,Nelson J Alvis-Zakzuk,Benny Antony,Malke Asaad,Till Winfried Bärnighausen,Sanjay Basu,Isabela M Bensenor,Zahid A Butt,Ismael R Campos-Nonato,Vijay Kumar Chattu,Michael H Criqui,Parnaz Daneshpajouhnejad,Claudio Alberto Dávila-Cervantes,Edgar Denova-Gutiérrez,Samath Dhamminda Dharmaratne,Daniel Diaz,Irina Filip,Mohamed M Gad,MA Garcia-Gordillo,Shakiba Ghasemi Assl,Sameer Vali Gopalani,Rafael Alves Guimarães,Rajat Das Gupta,Nima Hafezi-Nejad,Maryam Hashemian,Simon I Hay,Tanvir Kahlon,Jagdish Khubchandani,Ruth W Kimokoti,Adnan Kisa,Barthelemy Kuate Defo,Iván Landires,Ted R Miller,Ali H Mokdad,Linda Morales,Shane Douglas Morrison,Yeshambel T Nigatu,Virginia Nuñez-Samudio,Andrew T Olagunju,Seithikurippu R Pandi-Perumal,Urvish K Patel,Amir Radfar,Maria Rios-Blancas,Leonardo Roever,Seyedmohammad Saadatagah,Juan Sanabria,Itamar S Santos,Thirunavukkarasu Sathish,Mahsima Shabani,Omid Shafaat,Sara Sheikhbahaei,Diego Augusto Santos Silva,Ambrish Singh,Jasvinder A Singh,Marcos Roberto Tovani-Palone,Diana Zuleika Velazquez,Siddhesh Zadey,Mohsen Naghavi,Theo Vos,Bruce B Duncan

Journal

The lancet Diabetes & endocrinology

Published Date

2022/9/1

BackgroundHigh prevalence of diabetes has been reported in the Americas, but no comprehensive analysis of diabetes burden and related factors for the region is available. We aimed to describe the burden of type 1 and type 2 diabetes and that of hyperglycaemia in the Americas from 1990 to 2019.MethodsWe used estimates from GBD 2019 to evaluate the burden of diabetes in adults aged 20 years or older and high fasting plasma glucose in adults aged 25 years or older in the 39 countries and territories of the six regions in the Americas from 1990 to 2019. The main source to estimate the mortality attributable to diabetes and to chronic kidney disease due to diabetes was vital registration. Mortality due to overall diabetes (ie, diabetes and diabetes due to chronic kidney disease) was estimated using the Cause of Death Ensemble model. Years of life lost (YLLs) were calculated as the number of deaths multiplied …

A global systematic analysis of the occurrence, severity, and recovery pattern of long COVID in 2020 and 2021

Authors

Sarah Wulf Hanson,Cristiana Abbafati,Joachim G Aerts,Ziyad Al-Aly,Charlie Ashbaugh,Tala Ballouz,Oleg Blyuss,Polina Bobkova,Gouke Bonsel,Svetlana Borzakova,Danilo Buonsenso,Denis Butnaru,Austin Carter,Helen Chu,Cristina De Rose,Mohamed Mustafa Diab,Emil Ekbom,Maha El Tantawi,Victor Fomin,Robert Frithiof,Aysylu Gamirova,Petr V Glybochko,Juanita A Haagsma,Shaghayegh Haghjooy Javanmard,Erin B Hamilton,Gabrielle Harris,Majanka H Heijenbrok-Kal,Raimund Helbok,Merel E Hellemons,David Hillus,Susanne M Huijts,Michael Hultström,Waasila Jassat,Florian Kurth,Marie Larsson,Miklós Lipcsey,Chelsea Liu,Callan D Loflin,Andrei Malinovschi,Wenhui Mao,Lyudmila Mazankova,Denise McCulloch,Dominik Menges,Noushin Mohammadifard,Daniel Munblit,Nikita A Nekliudov,Osondu Ogbuoji,Ismail M Osmanov,José L Peñalvo,Maria Skaalum Petersen,Milo A Puhan,Mujibur Rahman,Verena Rass,Nickolas Reinig,Gerard M Ribbers,Antonia Ricchiuto,Sten Rubertsson,Elmira Samitova,Nizal Sarrafzadegan,Anastasia Shikhaleva,Kyle E Simpson,Dario Sinatti,Joan B Soriano,Ekaterina Spiridonova,Fridolin Steinbeis,Andrey A Svistunov,Piero Valentini,Brittney J van de Water,Rita van den Berg-Emons,Ewa Wallin,Martin Witzenrath,Yifan Wu,Hanzhang Xu,Thomas Zoller,Christopher Adolph,James Albright,Joanne O Amlag,Aleksandr Y Aravkin,Bree L Bang-Jensen,Catherine Bisignano,Rachel Castellano,Emma Castro,Suman Chakrabarti,James K Collins,Xiaochen Dai,Farah Daoud,Carolyn Dapper,Amanda Deen,Bruce B Duncan,Megan Erickson,Samuel B Ewald,Alize J Ferrari,Abraham D Flaxman,Nancy Fullman,Amiran Gamkrelidze,John R Giles,Gaorui Guo,Simon I Hay,Jiawei He,Monika Helak,Erin N Hulland,Maia Kereselidze,Kris J Krohn,Alice Lazzar-Atwood,Akiaja Lindstrom,Rafael Lozano,Beatrice Magistro,Deborah Carvalho Malta,Johan Månsson,Ana M Mantilla Herrera,Ali H Mokdad,Lorenzo Monasta,Shuhei Nomura,Maja Pasovic,David M Pigott,Robert C Reiner Jr,Grace Reinke,Antonio Luiz P Ribeiro,Damian Francesco Santomauro,Aleksei Sholokhov,Emma Elizabeth Spurlock,Rebecca Walcott,Ally Walker,Charles Shey Wiysonge,Peng Zheng,Janet Prvu Bettger,Christopher JL Murray,Theo Vos

Journal

MedRxiv

Published Date

2022/5/27

Objective:To estimate by country and territory of the number of patients affected by long COVID in 2020 and 2021, the severity of their symptoms and expected pattern of recoveryDesign:We jointly analyzed ten ongoing cohort studies in ten countries for the occurrence of three major symptom clusters of long COVID among representative COVID cases. The defining symptoms of the three clusters (fatigue, cognitive problems, and shortness of breath) are explicitly mentioned in the WHO clinical case definition. For incidence of long COVID, we adopted the minimum duration after infection of three months from the WHO case definition. We pooled data from the contributing studies, two large medical record databases in the United States, and findings from 44 published studies using a Bayesian meta-regression tool. We separately estimated occurrence and pattern of recovery in patients with milder acute infections and …

Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970–2019: a systematic analysis for the Global …

Authors

Annie Haakenstad,Olivia Angelino,Caleb MS Irvine,Zulfiqar A Bhutta,Kelly Bienhoff,Corinne Bintz,Kate Causey,M Ashworth Dirac,Nancy Fullman,Emmanuela Gakidou,Thomas Glucksman,Simon I Hay,Nathaniel J Henry,Ira Martopullo,Ali H Mokdad,John Everett Mumford,Stephen S Lim,Christopher JL Murray,Rafael Lozano

Journal

The Lancet

Published Date

2022/7/23

BackgroundMeeting the contraceptive needs of women of reproductive age is beneficial for the health of women and children, and the economic and social empowerment of women. Higher rates of contraceptive coverage have been linked to the availability of a more diverse range of contraceptive methods. We present estimates of the contraceptive prevalence rate (CPR), modern contraceptive prevalence rate (mCPR), demand satisfied, and the method of contraception used for both partnered and unpartnered women for 5-year age groups in 204 countries and territories between 1970 and 2019.MethodsWe used 1162 population-based surveys capturing contraceptive use among women between 1970 and 2019, in which women of reproductive age (15–49 years) self-reported their, or their partner's, current use of contraception for family planning purposes. Spatiotemporal Gaussian process regression was used …

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020

Authors

Dana Bryazka,Marissa B Reitsma,Max G Griswold,Kalkidan Hassen Abate,Cristiana Abbafati,Mohsen Abbasi-Kangevari,Zeinab Abbasi-Kangevari,Amir Abdoli,Mohammad Abdollahi,Abu Yousuf Md Abdullah,ES Abhilash,Eman Abu-Gharbieh,Juan Manuel Acuna,Giovanni Addolorato,Oladimeji M Adebayo,Victor Adekanmbi,Kishor Adhikari,Sangeet Adhikari,Qorinah Estiningtyas Sakilah Adnani,Saira Afzal,Wubetu Yimam Agegnehu,Manik Aggarwal,Bright Opoku Ahinkorah,Araz Ramazan Ahmad,Sajjad Ahmad,Tauseef Ahmad,Ali Ahmadi,Sepideh Ahmadi,Haroon Ahmed,Tarik Ahmed Rashid,Chisom Joyqueenet Akunna,Hanadi Al Hamad,Md Zakiul Alam,Dejene Tsegaye Alem,Kefyalew Addis Alene,Yousef Alimohamadi,Atiyeh Alizadeh,Kasim Allel,Jordi Alonso,Saba Alvand,Nelson Alvis-Guzman,Firehiwot Amare,Edward Kwabena Ameyaw,Sohrab Amiri,Robert Ancuceanu,Jason A Anderson,Catalina Liliana Andrei,Tudorel Andrei,Jalal Arabloo,Muhammad Arshad,Anton A Artamonov,Zahra Aryan,Malke Asaad,Mulusew A Asemahagn,Thomas Astell-Burt,Seyyed Shamsadin Athari,Desta Debalkie Atnafu,Prince Atorkey,Alok Atreya,Floriane Ausloos,Marcel Ausloos,Getinet Ayano,Martin Amogre ayanore Ayanore,Olatunde O Ayinde,Jose L Ayuso-Mateos,Sina Azadnajafabad,Melkalem Mamuye Azanaw,Mohammadreza Azangou-Khyavy,Amirhossein Azari Jafari,Ahmed Y Azzam,Ashish D Badiye,Nasser Bagheri,Sara Bagherieh,Mohan Bairwa,Shankar M Bakkannavar,Ravleen Kaur Bakshi,Awraris Hailu Balchut,Till Winfried Bärnighausen,Fabio Barra,Amadou Barrow,Pritish Baskaran,Luis Belo,Derrick A Bennett,Isabela M Benseñor,Akshaya Srikanth Bhagavathula,Neeraj Bhala,Ashish Bhalla,Nikha Bhardwaj,Pankaj Bhardwaj,Sonu Bhaskar,Krittika Bhattacharyya,Vijayalakshmi S Bhojaraja,Bagas Suryo Bintoro,Elena A Elena Blokhina,Belay Boda Abule Bodicha,Archith Boloor,Cristina Bosetti,Dejana Braithwaite,Hermann Brenner,Nikolay Ivanovich Briko,Andre R Brunoni,Zahid A Butt,Chao Cao,Yin Cao,Rosario Cárdenas,Andre F Carvalho,Márcia Carvalho,Joao Mauricio Castaldelli-Maia,Giulio Castelpietra,Luis FS Castro-de-Araujo,Maria Sofia Cattaruzza,Promit Ananyo Chakraborty,Jaykaran Charan,Vijay Kumar Chattu,Akhilanand Chaurasia,Nicolas Cherbuin,Dinh-Toi Chu,Nandita Chudal,Sheng-Chia Chung,Chuchu Churko,Liliana G Ciobanu,Massimo Cirillo,Rafael M Claro,Simona Costanzo,Richard G Cowden,Michael H Criqui,Natália Cruz-Martins,Garland T Culbreth,Berihun Assefa Dachew,Omid Dadras,Xiaochen Dai,Giovanni Damiani,Lalit Dandona,Rakhi Dandona,Beniam Darge Daniel,Anna Danielewicz,Jiregna Darega Gela,Kairat Davletov,Jacyra Azevedo Paiva de Araujo,Antonio Reis de Sá-Junior,Sisay Abebe Debela,Azizallah Dehghan,Andreas K Demetriades,Meseret Derbew Molla,Rupak Desai,Abebaw Alemayehu Desta,Diana Dias da Silva,Daniel Diaz,Lankamo Ena Digesa,Mengistie Diress

Journal

The Lancet

Published Date

2022/7/16

BackgroundThe health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year.MethodsFor this analysis, we constructed burden-weighted dose–response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15–95 years and older from 1990 to 2020. Based on the NDE, we quantified the …

Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990–2019: a systematic analysis from the …

Authors

Annie Haakenstad,Jamal Akeem Yearwood,Nancy Fullman,Corinne Bintz,Kelly Bienhoff,Marcia R Weaver,Vishnu Nandakumar,Jonah N Joffe,Kate E LeGrand,Megan Knight,Cristiana Abbafati,Mohsen Abbasi-Kangevari,Amir Abdoli,Roberto Ariel Abeldaño Zuñiga,Isaac Akinkunmi Adedeji,Victor Adekanmbi,Olatunji O Adetokunboh,Muhammad Sohail Afzal,Saira Afzal,Marcela Agudelo-Botero,Bright Opoku Ahinkorah,Sajjad Ahmad,Ali Ahmadi,Sepideh Ahmadi,Ali Ahmed,Tarik Ahmed Rashid,Budi Aji,Wuraola Akande-Sholabi,Khurshid Alam,Hanadi Al Hamad,Robert Kaba Alhassan,Liaqat Ali,Vahid Alipour,Syed Mohamed Aljunid,Edward Kwabena Ameyaw,Tarek Tawfik Amin,Hubert Amu,Dickson A Amugsi,Robert Ancuceanu,Pedro Prata Andrade,Afifa Anjum,Jalal Arabloo,Morteza Arab-Zozani,Hany Ariffin,Judie Arulappan,Zahra Aryan,Tahira Ashraf,Desta Debalkie Atnafu,Alok Atreya,Marcel Ausloos,Leticia Avila-Burgos,Getinet Ayano,Martin Amogre Ayanore,Samad Azari,Ashish D Badiye,Atif Amin Baig,Mohan Bairwa,Shankar M Bakkannavar,Shrikala Baliga,Palash Chandra Banik,Till Winfried Bärnighausen,Fabio Barra,Amadou Barrow,Sanjay Basu,Mohsen Bayati,Rebuma Belete,Arielle Wilder Bell,Devidas S Bhagat,Akshaya Srikanth Bhagavathula,Pankaj Bhardwaj,Nikha Bhardwaj,Sonu Bhaskar,Krittika Bhattacharyya,Zulfiqar A Bhutta,Sadia Bibi,Ali Bijani,Boris Bikbov,Antonio Biondi,Obasanjo Afolabi Bolarinwa,Aime Bonny,Hermann Brenner,Danilo Buonsenso,Katrin Burkart,Reinhard Busse,Zahid A Butt,Nadeem Shafique Butt,Florentino Luciano Caetano dos Santos,Lucero Cahuana-Hurtado,Luis Alberto Cámera,Rosario Cárdenas,Vera LA Carneiro,Ferrán Catalá-López,Joht Singh Chandan,Jaykaran Charan,Prachi P Chavan,Simiao Chen,Shu Chen,Sonali Gajanan Choudhari,Enayet Karim Chowdhury,Mohiuddin Ahsanul Kabir Chowdhury,Massimo Cirillo,Barbara Corso,Omid Dadras,Saad MA Dahlawi,Xiaochen Dai,Lalit Dandona,Rakhi Dandona,William James Dangel,Claudio Alberto Dávila-Cervantes,Kairat Davletov,Keshab Deuba,Meghnath Dhimal,Mandira Lamichhane Dhimal,Shirin Djalalinia,Huyen Phuc Do,Leila Doshmangir,Bruce B Duncan,Andem Effiong,Elham Ehsani-Chimeh,Islam Y Elgendy,Muhammed Elhadi,Iman El Sayed,Maha El Tantawi,Daniel Asfaw Erku,Sharareh Eskandarieh,Jawad Fares,Farshad Farzadfar,Simone Ferrero,Lorenzo Ferro Desideri,Florian Fischer,Nataliya A Foigt,Masoud Foroutan,Takeshi Fukumoto,Peter Andras Gaal,Santosh Gaihre,William M Gardner,Tushar Garg,Abera Getachew Obsa,Mansour Ghafourifard,Ahmad Ghashghaee,Nermin Ghith,Syed Amir Gilani,Paramjit Singh Gill,Salime Goharinezhad,Mahaveer Golechha,Jenny S Guadamuz,Yuming Guo,Rajat Das Gupta,Rajeev Gupta,Vivek Kumar Gupta

Journal

The Lancet global health

Published Date

2022/12/1

BackgroundHealth-care needs change throughout the life course. It is thus crucial to assess whether health systems provide access to quality health care for all ages. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019), we measured the Healthcare Access and Quality (HAQ) Index overall and for select age groups in 204 locations from 1990 to 2019.MethodsWe distinguished the overall HAQ Index (ages 0–74 years) from scores for select age groups: the young (ages 0–14 years), working (ages 15–64 years), and post-working (ages 65–74 years) groups. For GBD 2019, HAQ Index construction methods were updated to use the arithmetic mean of scaled mortality-to-incidence ratios (MIRs) and risk-standardised death rates (RSDRs) for 32 causes of death that should not occur in the presence of timely, quality health care. Across locations and years, MIRs and RSDRs were …

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21

Authors

Haidong Wang,Katherine R Paulson,Spencer A Pease,Stefanie Watson,Haley Comfort,Peng Zheng,Aleksandr Y Aravkin,Catherine Bisignano,Ryan M Barber,Tahiya Alam,John E Fuller,Erin A May,Darwin Phan Jones,Meghan E Frisch,Cristiana Abbafati,Christopher Adolph,Adrien Allorant,Joanne O Amlag,Bree Bang-Jensen,Gregory J Bertolacci,Sabina S Bloom,Austin Carter,Emma Castro,Suman Chakrabarti,Jhilik Chattopadhyay,Rebecca M Cogen,James K Collins,Kimberly Cooperrider,Xiaochen Dai,William James Dangel,Farah Daoud,Carolyn Dapper,Amanda Deen,Bruce B Duncan,Megan Erickson,Samuel B Ewald,Tatiana Fedosseeva,Alize J Ferrari,Joseph Jon Frostad,Nancy Fullman,John Gallagher,Amiran Gamkrelidze,Gaorui Guo,Jiawei He,Monika Helak,Nathaniel J Henry,Erin N Hulland,Bethany M Huntley,Maia Kereselidze,Alice Lazzar-Atwood,Kate E LeGrand,Akiaja Lindstrom,Emily Linebarger,Paulo A Lotufo,Rafael Lozano,Beatrice Magistro,Deborah Carvalho Malta,Johan Månsson,Ana M Mantilla Herrera,Fatima Marinho,Alemnesh H Mirkuzie,Awoke Temesgen Misganaw,Lorenzo Monasta,Paulami Naik,Shuhei Nomura,Edward G O'Brien,James Kevin O'Halloran,Latera Tesfaye Olana,Samuel M Ostroff,Louise Penberthy,Robert C Reiner Jr,Grace Reinke,Antonio Luiz P Ribeiro,Damian Francesco Santomauro,Maria Inês Schmidt,David H Shaw,Brittney S Sheena,Aleksei Sholokhov,Natia Skhvitaridze,Reed JD Sorensen,Emma Elizabeth Spurlock,Ruri Syailendrawati,Roman Topor-Madry,Christopher E Troeger,Rebecca Walcott,Ally Walker,Charles Shey Wiysonge,Nahom Alemseged Worku,Bethany Zigler,David M Pigott,Mohsen Naghavi,Ali H Mokdad,Stephen S Lim,Simon I Hay,Emmanuela Gakidou,Christopher JL Murray

Journal

The Lancet

Published Date

2022/4/16

BackgroundMortality statistics are fundamental to public health decision making. Mortality varies by time and location, and its measurement is affected by well known biases that have been exacerbated during the COVID-19 pandemic. This paper aims to estimate excess mortality from the COVID-19 pandemic in 191 countries and territories, and 252 subnational units for selected countries, from Jan 1, 2020, to Dec 31, 2021.MethodsAll-cause mortality reports were collected for 74 countries and territories and 266 subnational locations (including 31 locations in low-income and middle-income countries) that had reported either weekly or monthly deaths from all causes during the pandemic in 2020 and 2021, and for up to 11 year previously. In addition, we obtained excess mortality data for 12 states in India. Excess mortality over time was calculated as observed mortality, after excluding data from periods affected by …

Policy and technical considerations for implementing a risk-based approach to international travel in the context of COVID-19

Authors

Spencer L James,Degu Abate,Kalkidan Hassen Abate,Solomon M Abay,Cristiana Abbafati,Nooshin Abbasi,Hedayat Abbastabar,Foad Abd-Allah,Jemal Abdela,Ahmed Abdelalim,Ibrahim Abdollahpour,Rizwan Suliankatchi Abdulkader,Zegeye Abebe,Semaw Ferede Abera,Olifan Zewdie Abil,Haftom Niguse Abraha,Laith Jamal Abu-Raddad,Niveen ME Abu-Rmeileh,Manfred Mario Kokou Accrombessi,Dilaram Acharya,Pawan Acharya,Ilana N Ackerman,Abdu Abdullahi Adamu,Oladimeji M Adebayo,Victor Adekanmbi,Olatunji O Adetokunboh,Mina G Adib,Josef C Adsuar,Kossivi Agbelenko Afanvi,Mohsen Afarideh,Ashkan Afshin,Gina Agarwal,Kareha M Agesa,Rakesh Aggarwal,Sargis Aghasi Aghayan,Sutapa Agrawal,Alireza Ahmadi,Mehdi Ahmadi,Hamid Ahmadieh,Muktar Beshir Ahmed,Amani Nidhal Aichour,Ibtihel Aichour,Miloud Taki Eddine Aichour,Tomi Akinyemiju,Nadia Akseer,Ziyad Al-Aly,Ayman Al-Eyadhy,Hesham M Al-Mekhlafi,Rajaa M Al-Raddadi,Fares Alahdab,Khurshid Alam,Tahiya Alam,Alaa Alashi,Seyed Moayed Alavian,Kefyalew Addis Alene,Mehran Alijanzadeh,Reza Alizadeh-Navaei,Syed Mohamed Aljunid,Ala'a Alkerwi,François Francois Alla,Peter Allebeck,Mohamed ML Alouani,Khalid A Altirkawi,Nelson Alvis-Guzman,Azmeraw T Amare,Leopold N Aminde,Walid Ammar,Yaw Ampem Amoako,Nahla Hamed Anber,Catalina Liliana Andrei,Sofia Androudi,Megbaru Debalkie Animut,Mina Anjomshoa,Mustafa Geleto Ansha,Carl Abelardo TAT Antonio,Palwasha Anwari,Jalal Arabloo,Antonio Arauz,Olatunde Aremu,Filippo Ariani,Bahram Armoon,Johan Ärnlöv,Amit Arora,Al Artaman,Krishna Kumar Aryal,Hamid Asayesh,Rana Jawad Asghar,Zerihun Ataro,Sachin R Atre,Marcel Ausloos,Leticia Avila-Burgos,Euripide Frinel G Arthur FGA Avokpaho,Ashish Awasthi,Beatriz Paulina Ayala Quintanilla,Rakesh Ayer,Peter S Azzopardi,Arefeh Babazadeh,Hamid Badali,Alaa Badawi,Ayele Geleto Bali,Katherine E Ballesteros,Shoshana H Ballew,Maciej Banach,Joseph Adel Mattar Banoub,Amrit Banstola,Aleksandra Barac,Miguel A Barboza,Suzanne Lyn Barker-Collo,Till Winfried Bärnighausen,Lope H Barrero,Bernhard T Baune,Shahrzad Bazargan-Hejazi,Neeraj Bedi,Ettore Beghi,Meysam Masoud Behzadifar,Yannick Béjot,Abate Bekele Belachew,Yihalem Abebe Belay,Michelle L Bell,Aminu K Bello,Isabela M Bensenor,Eduardo Bernabe,Robert S Bernstein,Mircea Beuran,Tina Beyranvand,Neeraj Bhala,Suraj Bhattarai,Soumyadeep Soumyadeeep Bhaumik,Zulfiqar A Bhutta,Belete Biadgo,Ali Bijani,Boris Bikbov,Ver Bilano,Nigus Bililign,Muhammad Shahdaat Bin Sayeed,Donal Bisanzio,Brigette F Blacker,Fiona M Blyth,Ibrahim R Bou-Orm,Soufiane Boufous,Rupert RA Bourne,Oliver J Brady,Michael Brainin,Luisa C Brant,Alexandra Brazinova,Nicholas JK Breitborde,Hermann Brenner,Paul Svitil Briant,Adam DM Andrew M Briggs,Andrey Nikolaevich Briko

Journal

The Lancet

Published Date

2021

BACKGROUND The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. METHODS We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause …

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global …

Authors

Katherine R Paulson,Aruna M Kamath,Tahiya Alam,Kelly Bienhoff,Gdiom Gebreheat Abady,Jaffar Abbas,Mohsen Abbasi-Kangevari,Hedayat Abbastabar,Foad Abd-Allah,Sherief M Abd-Elsalam,Amir Abdoli,Aidin Abedi,Hassan Abolhassani,Lucas Guimarães Abreu,Eman Abu-Gharbieh,Niveen ME Abu-Rmeileh,Abdelrahman I Abushouk,Aishatu L Adamu,Oladimeji M Adebayo,Adeyinka Emmanuel Adegbosin,Victor Adekanmbi,Olatunji O Adetokunboh,Daniel Adedayo Adeyinka,Jose C Adsuar,Khashayar Afshari,Mohammad Aghaali,Marcela Agudelo-Botero,Bright Opoku Ahinkorah,Tauseef Ahmad,Keivan Ahmadi,Muktar Beshir Ahmed,Budi Aji,Yonas Akalu,Oluwaseun Oladapo Akinyemi,Addis Aklilu,Ziyad Al-Aly,Khurshid Alam,Fahad Mashhour Alanezi,Turki M Alanzi,Jacqueline Elizabeth Alcalde-Rabanal,Ayman Al-Eyadhy,Tilahun Ali,Gianfranco Alicandro,Sheikh Mohammad Alif,Vahid Alipour,Hesam Alizade,Syed Mohamed Aljunid,Amir Almasi-Hashiani,Nihad A Almasri,Hesham M Al-Mekhlafi,Jordi Alonso,Rajaa M Al-Raddadi,Khalid A Altirkawi,Arwa Khalid Alumran,Nelson Alvis-Guzman,Nelson J Alvis-Zakzuk,Edward Kwabena Ameyaw,Saeed Amini,Mostafa Amini-Rarani,Arianna Maever L Amit,Dickson A Amugsi,Robert Ancuceanu,Deanna Anderlini,Catalina Liliana Andrei,Fereshteh Ansari,Alireza Ansari-Moghaddam,Carl Abelardo T Antonio,Ernoiz Antriyandarti,Davood Anvari,Razique Anwer,Muhammad Aqeel,Jalal Arabloo,Morteza Arab-Zozani,Timur Aripov,Johan Ärnlöv,Kurnia Dwi Artanti,Afsaneh Arzani,Malke Asaad,Mehran Asadi-Aliabadi,Ali A Asadi-Pooya,Mohammad Asghari Jafarabadi,Seyyed Shamsadin Athari,Seyyede Masoume Athari,Desta Debalkie Atnafu,Alok Atreya,Madhu Sudhan Atteraya,Marcel Ausloos,Asma Tahir Awan,Beatriz Paulina Ayala Quintanilla,Getinet Ayano,Martin Amogre Ayanore,Yared Asmare Aynalem,Samad Azari,Ghasem Azarian,Zelalem Nigussie Azene,BB Darshan,Ebrahim Babaee,Ashish D Badiye,Atif Amin Baig,Maciej Banach,Palash Chandra Banik,Suzanne Lyn Barker-Collo,Hiba Jawdat Barqawi,Quique Bassat,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Neeraj Bedi,Ettore Beghi,Massimiliano Beghi,Michelle L Bell,Salaheddine Bendak,Derrick A Bennett,Isabela M Bensenor,Kidanemaryam Berhe,Adam E Berman,Yihienew Mequanint Bezabih,Akshaya Srikanth Bhagavathula,Dinesh Bhandari,Nikha Bhardwaj,Pankaj Bhardwaj,Krittika Bhattacharyya,Suraj Bhattarai,Zulfiqar A Bhutta,Boris Bikbov,Antonio Biondi,Binyam Minuye Birihane,Raaj Kishore Biswas,Somayeh Bohlouli,Nicola Luigi Bragazzi,Alexey V Breusov,Andre R Brunoni,Katrin Burkart,Sharath Burugina Nagaraja,Reinhard Busse,Zahid A Butt,Florentino Luciano Caetano Dos Santos,Lucero Cahuana-Hurtado,Paulo Camargos,Luis Alberto Camera,Rosario Cardenas,Giulia Carreras,Juan J Carrero,Felix Carvalho,Joao Mauricio Castaldelli-Maia,Carlos A Castaneda-Orjuela,Giulio Castelpietra,Ester Cerin,Jung-Chen Chang,Wagaye Fentahun Chanie

Journal

The Lancet

Published Date

2021/9/4

BackgroundSustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival.MethodsWe completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated …

Variation in health care access and quality among US states and high-income countries with universal health insurance coverage

Authors

Marcia R Weaver,Vishnu Nandakumar,Jonah Joffe,Ryan M Barber,Nancy Fullman,Arjun Singh,Gianna W Sparks,Jamal Yearwood,Rafael Lozano,Christopher JL Murray,Diana Ngo

Journal

JAMA Network Open

Published Date

2021/6/1

ImportanceBased on mortality estimates for 32 causes of death that are amenable to health care, the US health care system did not perform as well as other high-income countries, scoring 88.7 out of 100 on the 2016 age-standardized Healthcare Access and Quality (HAQ) index.ObjectiveTo compare US age-specific HAQ scores with those of high-income countries with universal health insurance coverage and compare scores among US states with varying insurance coverage.Design, Setting, and ParticipantsThis cross-sectional study used 2016 Global Burden of Diseases, Injuries, and Risk Factor study results for cause-specific mortality with adjustments for behavioral and environmental risks to estimate the age-specific HAQ indices. The US national age-specific HAQ scores were compared with high-income peers (Canada, western Europe, high-income Asia Pacific countries, and Australasia) in 1990, 2000 …

¿ Cuál será la primera causa de muerte en México en 2020?

Authors

Rafael Lozano,María Jesús Ríos-Blancas

Journal

Boletín sobre COVID-19

Published Date

2021

Con los datos disponibles hasta el momento, no es posible responder si COVID-19 será la primera causa de muerte en México, pero intuitivamente todo parece apuntar que sí lo será a nivel nacional y en la mayoría de las entidades federativas. Mucho depende de la forma de presentar la lista de las principales causas y de los métodos empleados para mejorar la calidad de los registros, pero lo más importante es haber cerrado la estadística de defunciones de 2020. Por lo regular, este procedimiento le toma al INEGI de 10 a 11 meses a partir de que se cierra el año calendario y posiblemente no cambie mucho la duración del procesamiento de registros, a pesar de que 2020 no es un año como los otros. Aunque no se trata de un ejercicio ortodoxo–ya que existe un desfase temporal en la ocurrencia de las defunciones-, los resultados pueden dar una idea del orden de importancia del COVID-19 a nivel nacional y por entidad federativa de acuerdo a su frecuencia. Cabe destacar que un análisis de las causas principales es solo un punto de partida en el análisis general del perfil de mortalidad de un país. Los trastornos demográficos ocasionados por la pandemia obligan a realizar innumerables análisis complementarios. Habrá que responder preguntas sobre el efecto en la esperanza de vida y conocer cuál será el exceso de muertes provocados por la pandemia durante 2020.

Integrated Measurement for Early Detection (MIDO) as a digital strategy for timely assessment of non-communicable disease profiles and factors associated with unawareness and …

Authors

Héctor Gallardo-Rincón,Alejandra Montoya,Rodrigo Saucedo-Martínez,Ricardo Mújica-Rosales,Lorena Suárez-Idueta,Luis Alberto Martínez-Juárez,Christian Razo,Rafael Lozano,Roberto Tapia-Conyer

Journal

BMJ open

Published Date

2021/9/1

ObjectivesThe Carlos Slim Foundation implemented the Integrated Measurement for Early Detection (MIDO), a screening strategy for non-communicable diseases (NCDs) in Mexico as part of CASALUD, a portfolio of digital health services focusing on healthcare delivery and prevention/management of NCDs. We investigated the disease profile of the screened population and evaluated MIDO’s contribution to the continuum of care of the main NCDs.DesignUsing data from MIDO and the chronic diseases information system, we quantified the proportion of the population screened and diagnosed with NCDs, and measured care linkage/retention and level of control achieved. We analysed comorbidity patterns and estimated prevalence of predisease stages. Finally, we estimated characteristics associated with unawareness and control of NCDs, and examined efficacy of the CASALUD model in improving NCD control …

Vaccination coverage estimation in Mexico in children under five years old: Trends and associated factors

Authors

Maria Jesus Rios-Blancas,Hector Lamadrid-Figueroa,Miguel Betancourt-Cravioto,Rafael Lozano

Journal

Plos one

Published Date

2021/4/16

We aimed to estimate vaccination coverage and factors associated in completing schemes in children under 5 years old between 2000 and 2018. A secondary analysis was carried out on five national health surveys between 2000 and 2018 in Mexico. The sample was 53,898 children under 5 years old, where 30% of missing vaccination information was imputed using chained equations. During this period two basic vaccination schemes (CBS) were identified. For each doses and vaccines of both schemes and completed CBS, the coverage was estimated using weighted logistic regression models. Additionally, the factors associated with incomplete schemes were reported. Between 2000 and 2018, the caretakers who did not show the vaccination card went from 13.8% to 45.6%. During this period, the estimated vaccination coverages did not exceed 95%, except for BCG and marginally the first doses of vaccines against pneumococcus, acellular pentavalent, and Sabin. In the same period, the CBS estimated coverage decreased steadily and was under 90%, except for children aged 6–11 months (92.6%; 91.5–93.7) in 2000. Not having health insurance stands out as an associated factor with incomplete vaccination schemes. In conclusion, the imputation allowed to recuperate information and obtain better data of vaccination coverage. The estimated vaccination coverage and CBS do not reach sufficient levels to guarantee herd immunity, hence innovative strategies to improve vaccination must be established in Mexico.

Modeling COVID-19 scenarios for the United States

Journal

Nature medicine

Published Date

2021/1

We use COVID-19 case and mortality data from 1 February 2020 to 21 September 2020 and a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental framework to model possible trajectories of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the effects of non-pharmaceutical interventions in the United States at the state level from 22 September 2020 through 28 February 2021. Using this SEIR model, and projections of critical driving covariates (pneumonia seasonality, mobility, testing rates and mask use per capita), we assessed scenarios of social distancing mandates and levels of mask use. Projections of current non-pharmaceutical intervention strategies by state—with social distancing mandates reinstated when a threshold of 8 deaths per million population is exceeded (reference scenario)—suggest that, cumulatively, 511,373 (469,578–578,347 …

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1

Authors

Natalie C Galles,Patrick Y Liu,Rachel L Updike,Nancy Fullman,Jason Nguyen,Sam Rolfe,Alyssa N Sbarra,Megan F Schipp,Ashley Marks,Gdiom Gebreheat Abady,Kaja M Abbas,Sumra Wajid Abbasi,Hedayat Abbastabar,Foad Abd-Allah,Amir Abdoli,Hassan Abolhassani,Akine Eshete Abosetugn,Maryam Adabi,Abdu A Adamu,Olatunji O Adetokunboh,Qorinah Estiningtyas Sakilah Adnani,Shailesh M Advani,Saira Afzal,Seyed Mohammad Kazem Aghamir,Bright Opoku Ahinkorah,Sohail Ahmad,Tauseef Ahmad,Sepideh Ahmadi,Haroon Ahmed,Muktar Beshir Ahmed,Tarik Ahmed Rashid,Yusra Ahmed Salih,Yonas Akalu,Addis Aklilu,Chisom Joyqueenet Akunna,Hanadi Al Hamad,Fares Alahdab,Luciana Albano,Yosef Alemayehu,Kefyalew Addis Alene,Ayman Al-Eyadhy,Robert Kaba Alhassan,Liaqat Ali,Syed Mohamed Aljunid,Sami Almustanyir,Khalid A Altirkawi,Nelson Alvis-Guzman,Hubert Amu,Catalina Liliana Andrei,Tudorel Andrei,Adnan Ansar,Alireza Ansari-Moghaddam,Ippazio Cosimo Antonazzo,Benny Antony,Jalal Arabloo,Morteza Arab-Zozani,Kurnia Dwi Artanti,Judie Arulappan,Asma Tahir Awan,Mamaru Ayenew Awoke,Muluken Altaye Ayza,Ghasem Azarian,Ahmed Y Azzam,BB Darshan,Senthilkumar Balakrishnan,Maciej Banach,Simachew Animen Bante,Till Winfried Bärnighausen,Hiba Jawdat Barqawi,Amadou Barrow,Quique Bassat,Narantuya Bayarmagnai,Diana Fernanda Bejarano Ramirez,Tariku Tesfaye Bekuma,Habtamu Gebrehana Belay,Uzma Iqbal Belgaumi,Akshaya Srikanth Bhagavathula,Dinesh Bhandari,Nikha Bhardwaj,Pankaj Bhardwaj,Sonu Bhaskar,Krittika Bhattacharyya,Sadia Bibi,Ali Bijani,Antonio Biondi,Archith Boloor,Dejana Braithwaite,Danilo Buonsenso,Zahid A Butt,Paulo Camargos,Giulia Carreras,Felix Carvalho,Carlos A Castañeda-Orjuela,Raja Chandra Chakinala,Jaykaran Charan,Souranshu Chatterjee,Soosanna Kumary Chattu,Vijay Kumar Chattu,Fazle Rabbi Chowdhury,Devasahayam J Christopher,Dinh-Toi Chu,Sheng-Chia Chung,Paolo Angelo Cortesi,Vera Marisa Costa,Rosa AS Couto,Omid Dadras,Amare Belachew Dagnew,Baye Dagnew,Xiaochen Dai,Lalit Dandona,Rakhi Dandona,Jan-Walter De Neve,Meseret Derbew Molla,Behailu Tariku Derseh,Rupak Desai,Abebaw Alemayehu Desta,Deepak Dhamnetiya,Mandira Lamichhane Dhimal,Meghnath Dhimal,Mostafa Dianatinasab,Daniel Diaz,Shirin Djalalinia,Fariba Dorostkar,Bassey Edem,Hisham Atan Edinur,Sahar Eftekharzadeh,Iman El Sayed,Maysaa El Sayed Zaki,Muhammed Elhadi,Shaimaa I El-Jaafary,Aisha Elsharkawy,Shymaa Enany,Ryenchindorj Erkhembayar,Christopher Imokhuede Esezobor,Sharareh Eskandarieh,Ifeanyi Jude Ezeonwumelu,Sayeh Ezzikouri,Jawad Fares,Pawan Sirwan Faris,Berhanu Elfu Feleke,Tomas Y Ferede,Eduarda Fernandes,João C Fernandes,Pietro Ferrara,Irina Filip,Florian Fischer,Mark Rohit Francis,Takeshi Fukumoto,Mohamed M Gad,Shilpa Gaidhane

Journal

The Lancet

Published Date

2021/8/7

BackgroundMeasuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time.MethodsFor this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific …

Assessing the continuum of care for maternal health in Mexico, 1994–2018

Authors

Edson Serván-Mori,Ileana Heredia-Pi,Diego Cerecero García,Gustavo Nigenda,Sandra G Sosa-Rubí,Jacqueline A Seiglie,Rafael Lozano

Journal

Bulletin of the World Health Organization

Published Date

2021/3/3

ObjectiveTo describe the temporal and geographical patterns of the continuum of maternal health care in Mexico, as well as the sociodemographic characteristics that affect the likelihood of receiving this care.MethodsWe conducted a pooled cross-sectional analysis using the 1997, 2009, 2014 and 2018 waves of the National Survey of Demographic Dynamics, collating sociodemographic and obstetric characteristics of 93 745 women aged 12–54 years at last delivery. We defined eight variables along the antenatal–postnatal continuum, both independently and conditionally. We used a pooled fixed-effects multivariable logistic model to determine the likelihood of receiving the continuum of care for various properties. We also mapped the quintiles of adjusted state-level absolute change in continuum of care coverage during 1994–2018.

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

Authors

Damian F Santomauro,Ana M Mantilla Herrera,Jamileh Shadid,Peng Zheng,Charlie Ashbaugh,David M Pigott,Cristiana Abbafati,Christopher Adolph,Joanne O Amlag,Aleksandr Y Aravkin,Bree L Bang-Jensen,Gregory J Bertolacci,Sabina S Bloom,Rachel Castellano,Emma Castro,Suman Chakrabarti,Jhilik Chattopadhyay,Rebecca M Cogen,James K Collins,Xiaochen Dai,William James Dangel,Carolyn Dapper,Amanda Deen,Megan Erickson,Samuel B Ewald,Abraham D Flaxman,Joseph Jon Frostad,Nancy Fullman,John R Giles,Ababi Zergaw Giref,Gaorui Guo,Jiawei He,Monika Helak,Erin N Hulland,Bulat Idrisov,Akiaja Lindstrom,Emily Linebarger,Paulo A Lotufo,Rafael Lozano,Beatrice Magistro,Deborah Carvalho Malta,Johan C Månsson,Fatima Marinho,Ali H Mokdad,Lorenzo Monasta,Paulami Naik,Shuhei Nomura,James Kevin O'Halloran,Samuel M Ostroff,Maja Pasovic,Louise Penberthy,Robert C Reiner Jr,Grace Reinke,Antonio Luiz P Ribeiro,Aleksei Sholokhov,Reed JD Sorensen,Elena Varavikova,Anh Truc Vo,Rebecca Walcott,Stefanie Watson,Charles Shey Wiysonge,Bethany Zigler,Simon I Hay,Theo Vos,Christopher JL Murray,Harvey A Whiteford,Alize J Ferrari

Journal

The Lancet

Published Date

2021/11/6

BackgroundBefore 2020, mental disorders were leading causes of the global health-related burden, with depressive and anxiety disorders being leading contributors to this burden. The emergence of the COVID-19 pandemic has created an environment where many determinants of poor mental health are exacerbated. The need for up-to-date information on the mental health impacts of COVID-19 in a way that informs health system responses is imperative. In this study, we aimed to quantify the impact of the COVID-19 pandemic on the prevalence and burden of major depressive disorder and anxiety disorders globally in 2020.MethodsWe conducted a systematic review of data reporting the prevalence of major depressive disorder and anxiety disorders during the COVID-19 pandemic and published between Jan 1, 2020, and Jan 29, 2021. We searched PubMed, Google Scholar, preprint servers, grey literature …

Trends and outcomes in primary health care expenditures in low-income and middle-income countries, 2000–2017

Authors

Matthew T Schneider,Angela Y Chang,Sawyer W Crosby,Stephen Gloyd,Anton C Harle,Stephen Lim,Rafael Lozano,Angela E Micah,Golsum Tsakalos,Yanfang Su,Christopher JL Murray,Joseph L Dieleman

Journal

BMJ global health

Published Date

2021/8/1

Introduction As the world responds to COVID-19 and aims for the Sustainable Development Goals, the potential for primary healthcare (PHC) is substantial, although the trends and effectiveness of PHC expenditure are unknown. We estimate PHC expenditure for each low-income and middle-income country between 2000 and 2017 and test which health outputs and outcomes were associated with PHC expenditure. Methods We used three data sources to estimate PHC expenditures: recently published health expenditure estimates for each low-income and middle-income country, which were constructed using 1662 country-reported National Health Accounts; proprietary data from IQVIA to estimate expenditure of prescribed pharmaceuticals for PHC; and household surveys and costing estimates to estimate inpatient vaginal delivery expenditures. We employed regression analyses to measure the association …

The invisible burden of violence against girls and young women in Mexico: 1990 to 2015

Authors

Martha P Romero Mendoza,Héctor Gómez-Dantes,Quetzaliztli Manríquez Montiel,Gabriela J Saldívar Hernández,Julio C Campuzano Rincón,Rafael Lozano,María Elena Medina-Mora Icaza

Journal

Journal of interpersonal violence

Published Date

2021/3

The increasing burden of interpersonal violence in women in Mexico is a neglected social and health problem that competes with other leading causes of premature death, disability, and health losses in young women. In this article, we focus on revealing the burden of violence in girls and young women and its implications for public policy. This study presents the subnational analysis of Mexico from the Global Burden of Disease study (1990-2015). The global study harmonized information of 195 countries and 79 risk factors. The study analyzed the deaths, years of life lost to premature death (YLL), years lived with disability (YLD), and the healthy years of life lost or disability-adjusted life year (DALY) related to violence. Nationwide, violence in young women accounts for 7% of all deaths in the 10 to 29 years age group and arises as the second most important cause of death in all age groups, except 10 to 14 years …

Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 …

Authors

Angela E Micah,Ian E Cogswell,Brandon Cunningham,Satoshi Ezoe,Anton C Harle,Emilie R Maddison,Darrah McCracken,Shuhei Nomura,Kyle E Simpson,Hayley N Stutzman,Golsum Tsakalos,Lindsey E Wallace,Yingxi Zhao,Rahul R Zende,Cristiana Abbafati,Michael Abdelmasseh,Aidin Abedi,Kedir Hussein Abegaz,ES Abhilash,Hassan Abolhassani,Michael RM Abrigo,Tara Ballav Adhikari,Saira Afzal,Bright Opoku Ahinkorah,Sepideh Ahmadi,Haroon Ahmed,Muktar Beshir Ahmed,Tarik Ahmed Rashid,Marjan Ajami,Budi Aji,Yonas Akalu,Chisom Joyqueenet Akunna,Hanadi Al Hamad,Khurshid Alam,Fahad Mashhour Alanezi,Turki M Alanzi,Yosef Alemayehu,Robert Kaba Alhassan,Cyrus Alinia,Syed Mohamed Aljunid,Sami Almustanyir Almustanyir,Nelson Alvis-Guzman,Nelson J Alvis-Zakzuk,Saeed Amini,Mostafa Amini-Rarani,Hubert Amu,Robert Ancuceanu,Catalina Liliana Andrei,Tudorel Andrei,Blake Angell,Mina Anjomshoa,Carl Abelardo T Antonio,Catherine M Antony,Muhammad Aqeel,Jalal Arabloo,Morteza Arab-Zozani,Timur Aripov,Alessandro Arrigo,Tahira Ashraf,Desta Debalkie Atnafu,Marcel Ausloos,Leticia Avila-Burgos,Asma Tahir Awan,Getinet Ayano,Martin Amogre Ayanore,Samad Azari,Gulrez Shah Azhar,Tesleem Kayode Babalola,Mohammad Amin Bahrami,Atif Amin Baig,Maciej Banach,Nastaran Barati,Till Winfried Bärnighausen,Amadou Barrow,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Habib Benzian,Adam E Berman,Akshaya Srikanth Bhagavathula,Nikha Bhardwaj,Pankaj Bhardwaj,Sonu Bhaskar,Sadia Bibi,Ali Bijani,Virginia Bodolica,Nicola Luigi Bragazzi,Dejana Braithwaite,Nicholas JK Breitborde,Alexey V Breusov,Nikolay Ivanovich Briko,Reinhard Busse,Lucero Cahuana-Hurtado,Emily Joy Callander,Luis Alberto Cámera,Carlos A Castañeda-Orjuela,Ferrán Catalá-López,Jaykaran Charan,Souranshu Chatterjee,Soosanna Kumary Chattu,Vijay Kumar Chattu,Simiao Chen,Arrigo Francesco Giuseppe Cicero,Omid Dadras,Saad MA Dahlawi,Xiaochen Dai,Koustuv Dalal,Lalit Dandona,Rakhi Dandona,Dragos Virgil Davitoiu,Jan-Walter De Neve,Antonio Reis de Sá-Junior,Edgar Denova-Gutierrez,Deepak Dhamnetiya,Samath Dhamminda Dharmaratne,Leila Doshmangir,John Dube,Elham Ehsani-Chimeh,Maysaa El Sayed Zaki,Maha El Tantawi,Sharareh Eskandarieh,Farshad Farzadfar,Tomas Y Ferede,Florian Fischer,Nataliya A Foigt,Alberto Freitas,Sara D Friedman,Takeshi Fukumoto,Nancy Fullman,Peter Andras Gaal,Mohamed M Gad,MA Garcia-Gordillo,Tushar Garg,Mansour Ghafourifard,Ahmad Ghashghaee,Asadollah Gholamian,Ali Gholamrezanezhad,Ghozali Ghozali,Syed Amir Gilani,Ionela-Roxana Glăvan,Ekaterina Vladimirovna Glushkova,Salime Goharinezhad,Mahaveer Golechha,Srinivas Goli,Avirup Guha,Veer Bala Gupta,Vivek Kumar Gupta,Annie Haakenstad,Mohammad Rifat Haider,Alemayehu Hailu

Published Date

2021/10/9

Background The rapid spread of COVID-19 renewed the focus on how health systems across the globe are financed, especially during public health emergencies. Development assistance is an important source of health financing in many low-income countries, yet little is known about how much of this funding was disbursed for COVID-19. We aimed to put development assistance for health for COVID-19 in the context of broader trends in global health financing, and to estimate total health spending from 1995 to 2050 and development assistance for COVID-19 in 2020. Methods We estimated domestic health spending and development assistance for health to generate total health-sector spending estimates for 204 countries and territories. We leveraged data from the WHO Global Health Expenditure Database to produce estimates of domestic health spending. To generate estimates for development assistance for …

Regional and state-level patterns of type 2 diabetes prevalence in Mexico over the last three decades

Authors

Jacqueline A Seiglie,Roxana Rodriguez Franco,Veronika J Wirtz,James B Meigs,Miguel Angel Mendoza,J Jaime Miranda,Héctor Gómez-Dantés,Rafael Lozano,Deborah J Wexler,Edson Serván-Mori

Journal

Diabetes research and clinical practice

Published Date

2021/7/1

AimsWe aimed to characterize and illustrate the regional and state-level change in type 2 diabetes (T2D) prevalence in Mexico between 1990 and 2017.MethodsWe conducted an ecological and secondary analysis using data from the Global Burden of Disease study on T2D prevalence of the adult Mexican population. We estimated the absolute increase and annual growth rate of T2D prevalence between 1990 and 2017, stratified by age group and region.ResultsNationally, between 1990 and 2017, the prevalence of T2D in Mexico increased from 9.5% to 14.3%. The highest increase in T2D prevalence was observed in the East and Southcentral regions, with the lowest absolute change in T2D prevalence observed in Northern states. The highest average annual growth rate in T2D prevalence was observed in Southern Mexico, in the three Southern states with the lowest human development index, and among …

Monitoring the progress of health-related sustainable development goals (SDGs) in Brazilian states using the Global Burden of Disease indicators

Authors

Daiane Borges Machado,Júlia Moreira Pescarini,Dandara Ramos,Renato Teixeira,Rafael Lozano,Vinicius Oliveira de Moura Pereira,Cimar Azeredo,Rômulo Paes-Sousa,Deborah Carvalho Malta,Mauricio L Barreto

Journal

Population health metrics

Published Date

2020/9

Background Measuring the Global Burden of Disease (GBD) has been the key to verifying the evolution of health indicators worldwide. We analyse subnational GBD data for Brazil in order to monitor the performance of the Brazilian states in the last 28 years on their progress towards meeting the health-related SDGs. Methods As part of the GBD study, we assessed the 41 health-related indicators from the SDGs in Brazil at the subnational level for all the 26 Brazilian states and the Federal District from 1990 to 2017. The GBD group has rescaled all worldwide indicators from 0 to 100, assuming that for each one of them, the worst value among all countries and overtime is 0, and the best is 100. They also estimate the overall health-related SDG index as a function of all previously estimated health indicators and the SDI index (Socio-Demographic Index) as …

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global …

Authors

Rafael Lozano,Nancy Fullman,John Everett Mumford,Megan Knight,Celine M Barthelemy,Cristiana Abbafati,Hedayat Abbastabar,Foad Abd-Allah,Mohammad Abdollahi,Aidin Abedi,Hassan Abolhassani,Akine Eshete Abosetugn,Lucas Guimarães Abreu,Michael RM Abrigo,Abdulaziz Khalid Abu Haimed,Abdelrahman I Abushouk,Maryam Adabi,Oladimeji M Adebayo,Victor Adekanmbi,Jaimie Adelson,Olatunji O Adetokunboh,Davoud Adham,Shailesh M Advani,Ashkan Afshin,Gina Agarwal,Pradyumna Agasthi,Seyed Mohammad Kazem Aghamir,Anurag Agrawal,Tauseef Ahmad,Rufus Olusola Akinyemi,Fares Alahdab,Ziyad Al-Aly,Khurshid Alam,Samuel B Albertson,Yihun Mulugeta Alemu,Robert Kaba Alhassan,Muhammad Ali,Saqib Ali,Vahid Alipour,Syed Mohamed Aljunid,François Alla,Majid Abdulrahman Hamad Almadi,Ali Almasi,Amir Almasi-Hashiani,Nihad A Almasri,Hesham M Al-Mekhlafi,Abdulaziz M Almulhim,Jordi Alonso,Rajaa M Al-Raddadi,Khalid A Altirkawi,Nelson Alvis-Guzman,Nelson J Alvis-Zakzuk,Saeed Amini,Mostafa Amini-Rarani,Fatemeh Amiri,Arianna Maever L Amit,Dickson A Amugsi,Robert Ancuceanu,Deanna Anderlini,Catalina Liliana Andrei,Sofia Androudi,Fereshteh Ansari,Alireza Ansari-Moghaddam,Carl Abelardo T Antonio,Catherine M Antony,Ernoiz Antriyandarti,Davood Anvari,Razique Anwer,Jalal Arabloo,Morteza Arab-Zozani,Aleksandr Y Aravkin,Olatunde Aremu,Johan Ärnlöv,Malke Asaad,Mehran Asadi-Aliabadi,Ali A Asadi-Pooya,Charlie Ashbaugh,Seyyed Shamsadin Athari,Maha Moh'd Wahbi Atout,Marcel Ausloos,Leticia Avila-Burgos,Beatriz Paulina Ayala Quintanilla,Getinet Ayano,Martin Amogre Ayanore,Yared Asmare Aynalem,Getie Lake Aynalem,Muluken Altaye Ayza,Samad Azari,Peter S Azzopardi,BB Darshan,Ebrahim Babaee,Ashish D Badiye,Mohammad Amin Bahrami,Atif Amin Baig,Mohammad Hossein Bakhshaei,Ahad Bakhtiari,Shankar M Bakkannavar,Arun Balachandran,Shelly Balassyano,Maciej Banach,Srikanta K Banerjee,Palash Chandra Banik,Agegnehu Bante Bante,Simachew Animen Bante,Suzanne Lyn Barker-Collo,Till Winfried Bärnighausen,Lope H Barrero,Quique Bassat,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Bayisa Abdissa Baye,Neeraj Bedi,Ettore Beghi,Masoud Behzadifar,Tariku Tesfaye Tesfaye Bekuma,Michelle L Bell,Isabela M Bensenor,Adam E Berman,Eduardo Bernabe,Robert S Bernstein,Akshaya Srikanth Bhagavathula,Dinesh Bhandari,Pankaj Bhardwaj,Anusha Ganapati Bhat,Krittika Bhattacharyya,Suraj Bhattarai,Zulfiqar A Bhutta,Ali Bijani,Boris Bikbov,Ver Bilano,Antonio Biondi,Binyam Minuye Birihane,Moses John Bockarie,Somayeh Bohlouli,Hunduma Amensisa Bojia,Srinivasa Rao Rao Bolla,Archith Boloor,Oliver J Brady,Dejana Braithwaite,Paul Svitil Briant,Andrew M Briggs,Nikolay Ivanovich Briko,Sharath Burugina Nagaraja,Reinhard Busse,Zahid A Butt,Florentino Luciano Caetano dos Santos,Lucero Cahuana-Hurtado,Luis Alberto Cámera,Rosario Cárdenas

Journal

The Lancet

Published Date

2020/10/17

Background Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority for both countries and global institutions, as highlighted by the agenda of the UN Sustainable Development Goals (SDGs) and WHO's Thirteenth General Programme of Work (GPW13). Measuring effective coverage at the health-system level is important for understanding whether health services are aligned with countries' health profiles and are of sufficient quality to produce health gains for populations of all ages. Methods Based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we assessed UHC effective coverage for 204 countries and territories from 1990 to 2019. Drawing from a measurement framework developed through WHO's GPW13 consultation, we …

Global projections of potential lives saved from COVID-19 through universal mask use

Authors

Emmanuela Gakidou,IHME COVID,Forecasting Team

Published Date

2020

BACKGROUNDSocial distancing mandates (SDM) have reduced health impacts from COVID-19 but also resulted in economic downturns that have led many nations to relax SDM. Until deployment of an efficacious and equitable vaccine, intervention options to reduce COVID-19 mortality and minimize restrictive SDM are sought by society. METHODSA susceptible-exposed-infectious-recovered (SEIR) deterministic transmission model was parameterized with data on reported deaths, cases, and select covariates to predict infections and deaths from COVID-19 through March 01, 2021. We explore three scenarios a" non-adaptive" scenario where neither mask use or SDM adapt to changing conditions, a" reference" where current national levels of mask use are maintained and SDM reintroduced when deaths rise, and an increase in mask use to 95% coverage levels (" universal mask"). We reviewed published studies to set priors on the magnitude of reduction in transmission through increasing mask use. RESULTSMask use was estimated at 59.0% of people globally on October 19, 2020. Universal mask use could avert 733,310 deaths (95% UI 385,981 to 1,107,759) between October 27, 2020 and March 01, 2021, the difference between the predicted 2.95 million deaths (95% UI 2.70 to 3.35) in the reference scenario and 2.22 million deaths (95% UI 2.00 to 2.45) in the universal mask scenario over this time period. CONCLUSIONSThe cumulative toll of the COVID-19 pandemic could be substantially reduced by the universal adoption of masks before the availability of a vaccine. This low-cost, low-barrier policy, whether customary or mandated …

Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: a forecasting analysis for the Global Burden of Disease Study

Authors

Stein Emil Vollset,Emily Goren,Chun-Wei Yuan,Jackie Cao,Amanda E Smith,Thomas Hsiao,Catherine Bisignano,Gulrez S Azhar,Emma Castro,Julian Chalek,Andrew J Dolgert,Tahvi Frank,Kai Fukutaki,Simon I Hay,Rafael Lozano,Ali H Mokdad,Vishnu Nandakumar,Maxwell Pierce,Martin Pletcher,Toshana Robalik,Krista M Steuben,Han Yong Wunrow,Bianca S Zlavog,Christopher JL Murray

Journal

The Lancet

Published Date

2020/10/17

BackgroundUnderstanding potential patterns in future population levels is crucial for anticipating and planning for changing age structures, resource and health-care needs, and environmental and economic landscapes. Future fertility patterns are a key input to estimation of future population size, but they are surrounded by substantial uncertainty and diverging methodologies of estimation and forecasting, leading to important differences in global population projections. Changing population size and age structure might have profound economic, social, and geopolitical impacts in many countries. In this study, we developed novel methods for forecasting mortality, fertility, migration, and population. We also assessed potential economic and geopolitical effects of future demographic shifts.MethodsWe modelled future population in reference and alternative scenarios as a function of fertility, migration, and mortality …

Life expectancy, death, and disability in Haiti, 1990-2017: a systematic analysis from the Global Burden of Disease Study 2017

Authors

Fato Fene,María Jesús Ríos-Blancas,James Lachaud,Christian Razo,Hector Lamadrid-Figueroa,Michael Liu,Jacob Michel,Roody Thermidor,Rafael Lozano

Journal

Revista panamericana de salud publica

Published Date

2020

Objective.To investigate the magnitude and distribution of the main causes of death, disability, and risk factors in Haiti.Methods.We conducted an ecological analysis, using data estimated from the Global Burden of Disease Study 2017 for the period 1990-2017, to present life expectancy (LE), healthy life expectancy (HALE) at under 1-year-old, cause-specific deaths, years of life lost (YLLs), years lived with disability (YLDs), disability adjusted life-years (DALYs), and risk factors associated with DALYs.Results.LE and HALE increased substantially in Haiti. People may hope to live longer in 2017, but in poor health. The Caribbean countries had significantly lower YLLs rates than Haiti for ischemic heart disease, stroke, lower respiratory infections, and diarrheal diseases. Road injuries were the leading cause of DALYs for people aged 5-14 years. Road injuries and HIV/AIDS were the leading causes of DALYs for men …

Effectiveness of adjunctive mother tinctures to individualized homeopathic treatment of chronic obstructive pulmonary diseases: an open randomized pragmatic pilot trial

Authors

Aniruddha Banerjee,Laijun Nahar,Showket Ahmad Bhat,Ashutosha Kumar,Rachna Goenka,Pralay Sharma,Swapan Paul,Abhijit Chattopadhyay,Sk Swaif Ali,Anamika Basu,James Michael,Munmun Koley,Subhranil Saha

Journal

Homoeopathic Links

Published Date

2020/3

Background We evaluated whether adjunctive mother tinctures (MTs) to individualized homeopathy (IH) have significant effect beyond IH alone in treatment of chronic obstructive pulmonary diseases (COPD). Methods An open, randomized (1:1; IH + MT versus IH only), two parallel arms, pragmatic trial (n = 60) was conducted at National Institute of Homoeopathy, India. Primary outcomes were forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC, measured at baseline and 6 months; secondary outcomes were Bengali COPD assessment test (CAT-B) questionnaire and (clinical COPD questionnaire) CCQ-B, measured at baseline, and after 3 and 6 months; and exacerbation frequencies during 6 months. Results Five patients dropped out (IH + MT: 3, IH: 2). Though intragroup changes were significant, intergroup differences of spirometric changes over 6 months were …

Advances and challenges on the path toward the SDGs: subnational inequalities in Mexico, 1990–2017

Authors

Juan Pablo Gutierrez,Marcela Agudelo-Botero,Sebastian Garcia-Saiso,Carolina Zepeda-Tena,Claudio Alberto Davila-Cervantes,Maria Cecilia Gonzalez-Robledo,Nancy Fullman,Christian Razo,Bernardo Hernández-Prado,Gabriel Martínez,Simón Barquera,Rafael Lozano

Published Date

2020/10/1

BackgroundThe sustainable development goals (SDGs) have generated momentum for global health, aligning efforts from governments and international organisations toward a set of goals that are expected to reflect improvements in life conditions across the globe. Mexico has huge social inequalities that can affect access to quality care and health outcomes. The objective of this study is to analyse inequalities among Mexico’s 32 states on the health-related SDG indicators (HRSDGIs) from 1990 to 2017.MethodsThese analyses rely on the estimation of HRSDGIs as part of the Global Burden of Disease study 2017. We estimated the concentration index for 40+3 HRSDGI stratified by Socio-demographic Index and marginalisation index, and then for indicators where inequalities were identified, we ran decomposition analyses using structural variables such as gross domestic product per capita, poverty and health …

Measurement matters: who and what counts on the road to universal health coverage

Authors

Nancy Fullman,Rafael Lozano

Journal

The Lancet Global Health

Published Date

2020/1/1

Advancing towards universal health coverage (UHC)—whereby all people receive the health services they need without financial hardship—is viewed as a primary way for countries to improve health and equity. 1, 2 Although UHC is often framed as bold yet achievable, questions remain on how best to monitor country-level gains and challenges. To make progress on the ground, we must understand where countries are today—in terms of both service coverage and financial risk protection—and what is needed to bring UHC closer to reality in the future.

The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Authors

Sadaf G Sepanlou,Saeid Safiri,Catherine Bisignano,Kevin S Ikuta,Shahin Merat,Mehdi Saberifiroozi,Hossein Poustchi,Derrick Tsoi,Danny V Colombara,Amir Abdoli,Rufus Adesoji Adedoyin,Mohsen Afarideh,Sutapa Agrawal,Sohail Ahmad,Elham Ahmadian,Ehsan Ahmadpour,Tomi Akinyemiju,Chisom Joyqueenet Akunna,Vahid Alipour,Amir Almasi-Hashiani,Abdulaziz M Almulhim,Rajaa M Al-Raddadi,Nelson Alvis-Guzman,Nahla Hamed Anber,Colin Angus,Amir Anoushiravani,Jalal Arabloo,Ephrem Mebrahtu Araya,Daniel Asmelash,Bahar Ataeinia,Zerihun Ataro,Maha Moh'd Wahbi Atout,Floriane Ausloos,Ashish Awasthi,Alaa Badawi,Maciej Banach,Diana Fernanda Bejarano Ramirez,Akshaya Srikanth Bhagavathula,Neeraj Bhala,Krittika Bhattacharyya,Antonio Biondi,Srinivasa Rao Bolla,Archith Boloor,Antonio M Borzì,Zahid A Butt,Luis LA Alberto Cámera,Ismael R Campos-Nonato,Félix Carvalho,Dinh-Toi Chu,Sheng-Chia Chung,Paolo Angelo Cortesi,Vera M Costa,Benjamin C Cowie,Ahmad Daryani,Barbora de Courten,Gebre Teklemariam Demoz,Rupak Desai,Samath Dhamminda Dharmaratne,Shirin Djalalinia,Hoa Thi Do,Fariba Dorostkar,Thomas M Drake,Manisha Dubey,Bruce B Duncan,Andem Effiong,Aziz Eftekhari,Aisha Elsharkawy,Arash Etemadi,Mohammad Farahmand,Farshad Farzadfar,Eduarda Fernandes,Irina Filip,Florian Fischer,Ketema Bizuwork Bizuwork Gebremedhin,Birhanu Geta,Syed Amir Gilani,Paramjit Singh Gill,Reyna Alma Gutirrez,Michael Tamene Haile,Arvin Haj-Mirzaian,Saeed S Hamid,Milad Hasankhani,Amir Hasanzadeh,Maryam Hashemian,Hamid Yimam Hassen,Simon I Hay,Khezar Hayat,Behnam Heidari,Andualem Henok,Chi Linh Hoang,Mihaela Hostiuc,Sorin Hostiuc,Vivian Chia-rong Hsieh,Ehimario U Igumbor,Olayinka Stephen Ilesanmi,Seyed Sina Naghibi Irvani,Nader Jafari Balalami,Spencer L James,Panniyammakal Jeemon,Ravi Prakash Jha,Jost B Jonas,Jacek Jerzy Jozwiak,Ali Kabir,Amir Kasaeian,Hagazi Gebremedhin Kassaye,Adane Teshome Kefale,Rovshan Khalilov,Muhammad Ali Khan,Ejaz Ahmad Khan,Amir Khater,Yun Jin Kim,Ai Koyanagi,Carlo La Vecchia,Lee-Ling Lim,Alan D Lopez,Stefan Lorkowski,Paulo A Lotufo,Rafael Lozano,Muhammed Magdy Abd El Razek,Hue Thi Mai,Navid Manafi,Amir Manafi,Mohammad Ali Mansournia,Lorenzo Giovanni Mantovani,Giampiero Mazzaglia,Dhruv Mehta,Walter Mendoza,Ritesh G Menezes,Melkamu Merid Mengesha,Tuomo J Meretoja,Tomislav Mestrovic,Bartosz Miazgowski,Ted R Miller,Erkin M Mirrakhimov,Prasanna Mithra,Babak Moazen,Masoud Moghadaszadeh,Abdollah Mohammadian-Hafshejani,Shafiu Mohammed,Ali H Mokdad,Pablo A Montero-Zamora,Ghobad Moradi,Mukhammad David Naimzada,Vinod Nayak,Ionut Negoi,Trang Huyen Nguyen,Richard Ofori-Asenso,In-Hwan Oh,Tinuke O Olagunju,Jagadish Rao Padubidri

Journal

The Lancet gastroenterology & hepatology

Published Date

2020/3/1

BackgroundCirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We report on results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 on the burden of cirrhosis and its trends since 1990, by cause, sex, and age, for 195 countries and territories.MethodsWe used data from vital registrations, vital registration samples, and verbal autopsies to estimate mortality. We modelled prevalence of total, compensated, and decompensated cirrhosis on the basis of hospital and claims data. Disability-adjusted life-years (DALYs) were calculated as the sum of years of life lost due to premature death and years lived with disability. Estimates are presented as numbers and age-standardised or age-specific rates per …

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic …

Authors

Haidong Wang,Kaja M Abbas,Mitra Abbasifard,Mohsen Abbasi-Kangevari,Hedayat Abbastabar,Foad Abd-Allah,Ahmed Abdelalim,Hassan Abolhassani,Lucas Guimarães Abreu,Michael RM Abrigo,Abdelrahman I Abushouk,Maryam Adabi,Tim Adair,Oladimeji M Adebayo,Isaac Akinkunmi Adedeji,Victor Adekanmbi,Abiodun Moshood Adeoye,Olatunji O Adetokunboh,Shailesh M Advani,Ashkan Afshin,Mohammad Aghaali,Anurag Agrawal,Keivan Ahmadi,Hamid Ahmadieh,Muktar Beshir Ahmed,Ziyad Al-Aly,Khurshid Alam,Tahiya Alam,Fahad Mashhour Alanezi,Turki M Alanzi,Jacqueline Elizabeth Alcalde-Rabanal,Muhammad Ali,Gianfranco Alicandro,Mehran Alijanzadeh,Cyrus Alinia,Vahid Alipour,Hesam Alizade,Syed Mohamed Aljunid,Peter Allebeck,Majid Abdulrahman Hamad Almadi,Amir Almasi-Hashiani,Hesham M Al-Mekhlafi,Khalid A Altirkawi,Arwa Khalid Alumran,Nelson Alvis-Guzman,Mostafa Amini-Rarani,Arya Aminorroaya,Arianna Maever L Amit,Robert Ancuceanu,Catalina Liliana Andrei,Sofia Androudi,Colin Angus,Mina Anjomshoa,Fereshteh Ansari,Iman Ansari,Alireza Ansari-Moghaddam,Carl Abelardo T Antonio,Catherine M Antony,Davood Anvari,Seth Christopher Yaw Appiah,Jalal Arabloo,Morteza Arab-Zozani,Aleksandr Y Aravkin,Olatunde Aremu,Johan Ärnlöv,Krishna K Aryal,Ali A Asadi-Pooya,Samaneh Asgari,Mohammad Asghari Jafarabadi,Madhu Sudhan Atteraya,Marcel Ausloos,Leticia Avila-Burgos,Euripide Frinel Gbenato Arthur Avokpaho,Beatriz Paulina Ayala Quintanilla,Getinet Ayano,Martin Amogre Ayanore,Ghasem Azarian,Ebrahim Babaee,Ashish D Badiye,Eleni Bagli,Mohammad Amin Bahrami,Ahad Bakhtiari,Shelly Balassyano,Maciej Banach,Palash Chandra Banik,Suzanne Lyn Barker-Collo,Till Winfried Bärnighausen,Akbar Barzegar,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Gholamreza Bazmandegan,Neeraj Bedi,Michellr L Bell,Derrick A Bennett,Isabela M Bensenor,Kidanemaryam Berhe,Adam E Berman,Gregory J Bertolacci,Reshmi Bhageerathy,Neeraj Bhala,Krittika Bhattacharyya,Zulfiqar A Bhutta,Ali Bijani,Antonio Biondi,Donal Bisanzio,Catherine Bisignano,Raaj Kishore Biswas,Tone Bjørge,Somayeh Bohlouli,Mehdi Bohluli,Srinivasa Rao Rao Bolla,Antonio Maria Borzì,Shiva Borzouei,Oliver J Brady,Dejana Braithwaite,Michael Brauer,Andrey Nikolaevich Briko,Nikolay Ivanovich Briko,Blair R Bumgarner,Sharath Burugina Nagaraja,Zahid A Butt,Florentino Luciano Caetano dos Santos,Tianji Cai,Charlton SKH Callender,Luis LA Alberto Cámera,Ismael R Campos-Nonato,Rosario Cárdenas,Giulia Carreras,Juan J Carrero,Felix Carvalho,Joao Mauricio Castaldelli-Maia,Giulio Castelpietra,Franz Castro,Ferran Catala-Lopez,Christopher R Cederroth,Ester Cerin,Vijay Kumar Chattu,Ken Lee Chin,Dinh-Toi Chu,Liliana G Ciobanu,Massimo Cirillo,Haley Comfort,Vera Marisa Costa,Richard G Cowden,Elizabeth A Cromwell,Andrew J Croneberger,Matthew Cunningham,Saad MA Dahlawi,Giovanni Damiani

Journal

The Lancet

Published Date

2020/10/17

BackgroundAccurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019.Methods8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10–14 and 50–54 years, the total fertility rate (TFR) was …

Unintentional injuries in Mexico, 1990–2017: findings from the Global Burden of Disease Study 2017

Authors

Martha Híjar,Ricardo Pérez-Núñez,Elisa Hidalgo-Solórzano,Bernardo Hernández Prado,Rosario Valdez-Santiago,Erin B Hamilton,Spencer L James,Gregory J Bertolacci,Matthew Cunningham,Zachary V Dingels,Jack T Fox,Zichen Liu,Nicholas LS Roberts,Dillon O Sylte,Marcela Agudelo-Botero,Guilherme Borges,Lucero Cahuana-Hurtado,Ismael R Campos-Nonato,Rosario Cárdenas,Claudio Alberto Dávila-Cervantes,Edgar Denova-Gutiérrez,Daniel Diaz,Van C Lansingh,Gabriel Martinez,Pablo A Montero-Zamora,Edson Serván-Mori,Rafael Lozano

Journal

Injury prevention

Published Date

2020/10/1

Background To date, the burden of injury in Mexico has not been comprehensively assessed using recent advances in population health research, including those in the Global Burden of Disease Study 2017 (GBD 2017).Methods We used GBD 2017 for burden of unintentional injury estimates, including transport injuries, for Mexico and each state in Mexico from 1990 to 2017. We examined subnational variation, age patterns, sex differences and time trends for all injury burden metrics.Results Unintentional injury deaths in Mexico decreased from 45 363 deaths (44 662 to 46 038) in 1990 to 42 702 (41 439 to 43 745) in 2017, while age-standardised mortality rates decreased from 65.2 (64.4 to 66.1) in 1990 to 35.1 (34.1 to 36.0) per 100 000 in 2017. In terms of non-fatal outcomes, there were 3 120 211 (2 879 993 to 3 377 945) new injury cases in 1990, which increased to 5 234 214 (4 812 615 to 5 701 669) new …

Monitoring the health-related Sustainable Development Goals: lessons learned and recommendations for improved measurement

Authors

Samira Asma,Rafael Lozano,Somnath Chatterji,Soumya Swaminathan,Maria de Fátima Marinho,Naoko Yamamoto,Elena Varavikova,Awoke Misganaw,Michael Ryan,Lalit Dandona,Ren Minghui,Christopher JL Murray

Published Date

2020/1/18

BackgroundThe UN General Assembly launched the Sustainable Development Goals (SDGs) in September, 2015. 1 The origi nal global SDG framework included 17 goals, 169 targets, and 232 unique indicators. 2 Of these, 12 goals, 33 targets, and 57 indicators have been identified as healthrelated SDGs (HRSDGs), 3–6 that is, pertaining to health outcomes, health services, and wellestablished environ mental, occu pa tional, behavioural, and metabolic risks. The scope of health in the SDGs is much broader than in the Millennium Development Goals, spanning from maternal and child health and infectious diseases to noncommunicable dis eases, injuries, risk factors, and healthsystem functions. Regular monitoring of the HRSDGs is important for fostering a shared notion of accountability for results, identifying important gaps in resources and rates of pro gress, and taking into account emerging challenges that …

Five insights from the global burden of disease study 2019

Authors

Christopher JL Murray,Cristiana Abbafati,Kaja M Abbas,Mohammad Abbasi,Mohsen Abbasi-Kangevari,Foad Abd-Allah,Mohammad Abdollahi,Parisa Abedi,Aidin Abedi,Hassan Abolhassani,Victor Aboyans,Lucas Guimarães Abreu,Michael RM Abrigo,Eman Abu-Gharbieh,Abdulaziz Khalid Abu Haimed,Abdelrahman I Abushouk,Alyssa Acebedo,Ilana N Ackerman,Maryam Adabi,Abdu A Adamu,Oladimeji M Adebayo,Jaimie D Adelson,Olatunji O Adetokunboh,Mohsen Afarideh,Ashkan Afshin,Gina Agarwal,Anurag Agrawal,Tauseef Ahmad,Keivan Ahmadi,Mehdi Ahmadi,Muktar Beshir Ahmed,Budi Aji,Tomi Akinyemiju,Blessing Akombi,Fares Alahdab,Khurshid Alam,Fahad Mashhour Alanezi,Turki M Alanzi,Samuel B Albertson,Biresaw Wassihun Alemu,Yihun Mulugeta Alemu,Khalid F Alhabib,Muhammad Ali,Saqib Ali,Gianfranco Alicandro,Vahid Alipour,Hesam Alizade,Syed Mohamed Aljunid,François Alla,Peter Allebeck,Majid Abdulrahman Hamad Almadi,Amir Almasi-Hashiani,Hesham M Al-Mekhlafi,Abdulaziz M Almulhim,Jordi Alonso,Rajaa M Al-Raddadi,Khalid A Altirkawi,Nelson Alvis-Guzman,Bekalu Amare,Azmeraw T Amare,Saeed Amini,Arianna Maever L Amit,Dickson A Amugsi,Etsay Woldu Anbesu,Robert Ancuceanu,Deanna Anderlini,Jason A Anderson,Tudorel Andrei,Catalina Liliana Andrei,Mina Anjomshoa,Fereshteh Ansari,Alireza Ansari-Moghaddam,Carl Abelardo T Antonio,Catherine M Antony,Davood Anvari,Seth Christopher Yaw Appiah,Jalal Arabloo,Morteza Arab-Zozani,Aleksandr Y Aravkin,Aseb Arba Kinfe Arba,Timur Aripov,Johan Ärnlöv,Oluwaseyi Olalekan Arowosegbe,Malke Asaad,Mehran Asadi-Aliabadi,Ali A Asadi-Pooya,Charlie Ashbaugh,Michael Assmus,Maha Moh'd Wahbi Atout,Marcel Ausloos,Floriane Ausloos,Beatriz Paulina Ayala Quintanilla,Getinet Ayano,Martin Amogre Ayanore,Samad Azari,Zelalem Nigussie Azene,BB Darshan,Ebrahim Babaee,Alaa Badawi,Ashish D Badiye,Mojtaba Bagherzadeh,Mohan Bairwa,Ahad Bakhtiari,Shankar M Bakkannavar,Arun Balachandran,Maciej Banach,Srikanta K Banerjee,Palash Chandra Banik,Adhanom Gebreegziabher Baraki,Suzanne Lyn Barker-Collo,Huda Basaleem,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Bayisa Abdissa Baye,Neeraj Bedi,Ettore Beghi,Michellr L Bell,Isabela M Bensenor,Kidanemaryam Berhe,Adam E Berman,Akshaya Srikanth Bhagavathula,Neeraj Bhala,Pankaj Bhardwaj,Krittika Bhattacharyya,Suraj Bhattarai,Zulfiqar A Bhutta,Ali Bijani,Boris Bikbov,Antonio Biondi,Catherine Bisignano,Raaj Kishore Biswas,Tone Bjørge,Somayeh Bohlouli,Mehdi Bohluli,Srinivasa Rao Rao Bolla,Archith Boloor,Dipan Bose,Soufiane Boufous,Oliver J Brady,Dejana Braithwaite,Michael Brauer,Nicholas JK Breitborde,Hermann Brenner,Alexey V Breusov,Paul Svitil Briant,Andrew M Briggs,Gabrielle B Britton,Traolach Brugha,Sharath Burugina Nagaraja

Published Date

2020/10/17

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3·5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD …

Health sector spending and spending on HIV/AIDS, tuberculosis, and malaria, and development assistance for health: progress towards Sustainable Development Goal 3

Authors

Angela E Micah,Yanfang Su,Steven D Bachmeier,Abigail Chapin,Ian E Cogswell,Sawyer W Crosby,Brandon Cunningham,Anton C Harle,Emilie R Maddison,Modhurima Moitra,Maitreyi Sahu,Matthew T Schneider,Kyle E Simpson,Hayley N Stutzman,Golsum Tsakalos,Rahul R Zende,Bianca S Zlavog,Cristiana Abbafati,Zeleke Hailemariam Abebo,Hassan Abolhassani,Michael RM Abrigo,Muktar Beshir Ahmed,Rufus Olusola Akinyemi,Khurshid Alam,Saqib Ali,Cyrus Alinia,Vahid Alipour,Syed Mohamed Aljunid,Ali Almasi,Nelson Alvis-Guzman,Robert Ancuceanu,Tudorel Andrei,Catalina Liliana Andrei,Mina Anjomshoa,Carl Abelardo T Antonio,Jalal Arabloo,Morteza Arab-Zozani,Olatunde Aremu,Desta Debalkie Atnafu,Marcel Ausloos,Leticia Avila-Burgos,Martin Amogre Ayanore,Samad Azari,Tesleem Kayode Babalola,Mojtaba Bagherzadeh,Atif Amin Baig,Ahad Bakhtiari,Maciej Banach,Srikanta K Banerjee,Till Winfried Bärnighausen,Sanjay Basu,Bernhard T Baune,Mohsen Bayati,Adam E Berman,Reshmi Bhageerathy,Pankaj Bhardwaj,Mehdi Bohluli,Reinhard Busse,Lucero Cahuana-Hurtado,Luis LA Alberto Cámera,Carlos A Castañeda-Orjuela,Ferrán Catalá-López,Muge Cevik,Vijay Kumar Chattu,Lalit Dandona,Rakhi Dandona,Mostafa Dianatinasab,Hoa Thi Do,Leila Doshmangir,Maha El Tantawi,Sharareh Eskandarieh,Firooz Esmaeilzadeh,Anwar Faraj,Farshad Farzadfar,Florian Fischer,Nataliya A Foigt,Nancy Fullman,Mohamed M Gad,Mansour Ghafourifard,Ahmad Ghashghaee,Asadollah Gholamian,Salime Goharinezhad,Ayman Grada,Hassan Haghparast Bidgoli,Samer Hamidi,Hilda L Harb,Edris Hasanpoor,Simon I Hay,Delia Hendrie,Nathaniel J Henry,Claudiu Herteliu,Michael K Hole,Mehdi Hosseinzadeh,Sorin Hostiuc,Tanvir M Huda,Ayesha Humayun,Bing-Fang Hwang,Olayinka Stephen Ilesanmi,Usman Iqbal,Seyed Sina N Irvani,Sheikh Mohammed Shariful Islam,M Mofizul Islam,Mohammad Ali Jahani,Mihajlo Jakovljevic,Spencer L James,Zohre Javaheri,Jost B Jonas,Farahnaz Joukar,Jacek Jerzy Jozwiak,Mikk Jürisson,Rohollah Kalhor,Behzad Karami Matin,Salah Eddin Karimi,Gbenga A Kayode,Ali Kazemi Karyani,Yohannes Kinfu,Adnan Kisa,Stefan Kohler,Hamidreza Komaki,Soewarta Kosen,Anirudh Kotlo,Ai Koyanagi,G Anil Kumar,Dian Kusuma,Van C Lansingh,Anders O Larsson,Savita Lasrado,Shaun Wen Huey Lee,Lee-Ling Lim,Rafael Lozano,Hassan Magdy Abd El Razek,Mokhtar Mahdavi Mahdavi,Shokofeh Maleki,Reza Malekzadeh,Fariborz Mansour-Ghanaei,Mohammad Ali Mansournia,Lorenzo Giovanni Mantovani,Gabriel Martinez,Seyedeh Zahra Masoumi,Benjamin Ballard Massenburg,Ritesh G Menezes,Endalkachew Worku Mengesha,Tuomo J Meretoja,Atte Meretoja,Tomislav Mestrovic,Neda Milevska Kostova,Ted R Miller,Andreea Mirica,Erkin M Mirrakhimov,Masoud Moghadaszadeh

Journal

The Lancet

Published Date

2020/9/5

Summary Background Sustainable Development Goal (SDG) 3 aims to" ensure healthy lives and promote well-being for all at all ages". While a substantial effort has been made to quantify progress towards SDG3, less research has focused on tracking spending towards this goal. We used spending estimates to measure progress in financing the priority areas of SDG3, examine the association between outcomes and financing, and identify where resource gains are most needed to achieve the SDG3 indicators for which data are available. Methods We estimated domestic health spending, disaggregated by source (government, out-of-pocket, and prepaid private) from 1995 to 2017 for 195 countries and territories. For disease-specific health spending, we estimated spending for HIV/AIDS and tuberculosis for 135 low-income and middle-income countries, and malaria in 106 malaria-endemic countries, from 2000 to …

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

Authors

Kristina E Rudd,Sarah Charlotte Johnson,Kareha M Agesa,Katya Anne Shackelford,Derrick Tsoi,Daniel Rhodes Kievlan,Danny V Colombara,Kevin S Ikuta,Niranjan Kissoon,Simon Finfer,Carolin Fleischmann-Struzek,Flavia R Machado,Konrad K Reinhart,Kathryn Rowan,Christopher W Seymour,R Scott Watson,T Eoin West,Fatima Marinho,Simon I Hay,Rafael Lozano,Alan D Lopez,Derek C Angus,Christopher JL Murray,Mohsen Naghavi

Journal

The Lancet

Published Date

2020/1/18

BackgroundSepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the global burden of sepsis are limited. As a syndrome caused by underlying infection, sepsis is not part of standard Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimates. Accurate estimates are important to inform and monitor health policy interventions, allocation of resources, and clinical treatment initiatives. We estimated the global, regional, and national incidence of sepsis and mortality from this disorder using data from GBD 2017.MethodsWe used multiple cause-of-death data from 109 million individual death records to calculate mortality related to sepsis among each of the 282 underlying causes of death in GBD 2017. The percentage of sepsis-related deaths by underlying GBD cause in each location worldwide was …

See List of Professors in Rafael Lozano University(University of Washington)

Rafael Lozano FAQs

What is Rafael Lozano's h-index at University of Washington?

The h-index of Rafael Lozano has been 92 since 2020 and 114 in total.

What are Rafael Lozano's top articles?

The articles with the titles of

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in …

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the …

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the …

A gender-based and quasi-experimental study of the catastrophic and impoverishing health-care expenditures in Mexican households with elderly members, 2000-2020

Burden, Incidence, Mortality and Lethality of Maternal Disorders in Mexico 1990-2019: An Analysis for the Global Burden of Disease Study 2019

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

The burden of disease, injuries, and risk factors in Mexico: 1990-2021 update

La carga de la enfermedad, lesiones y factores de riesgo en México. Actualización del período 1990-2021

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are the top articles of Rafael Lozano at University of Washington.

What are Rafael Lozano's research interests?

The research interests of Rafael Lozano are: Health Metrics, Global Health, Burden of Disease, Latin America, Mexico

What is Rafael Lozano's total number of citations?

Rafael Lozano has 232,985 citations in total.

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